Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Mitsuko Hirosawa"'
Publikováno v:
Epigenetics & Chromatin, Vol 10, Iss 1, Pp 1-14 (2017)
Abstract Background We have previously reported a novel O-GlcNAc modification at serine 40 (S40) of H2A (H2AS40Gc). S40-type H2A isoforms susceptible to O-GlcNAcylation are evolutionarily new and restricted to the viviparous animals; however, the bio
Externí odkaz:
https://doaj.org/article/8336b42b1ea24f2a8ebbc6b676970804
Autor:
Mitsuko Hirosawa, Satoshi Tanaka, Koji Hayakawa, Daisuke Arai, Yoichi Nakao, Jun Ohgane, Kunio Shiota
Publikováno v:
Mechanisms of Development. 136:143-154
Nodal signaling plays critical roles during embryonic development. The Nodal gene is not expressed in adult tissues but is frequently activated in cancer cells, contributing to progression toward malignancy. Although several regulatory elements of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23e59220a54757f8d3a37160acc0c74c
Autor:
Yasuyuki Tabei, Kunio Shiota, Mitsuko Hirosawa, Koji Hayakawa, Shintaro Yagi, Daisuke Arai, Noboru Murakami, Satoshi Tanaka
Publikováno v:
Journal of Biological Chemistry. 288:17099-17110
The orexin system plays a central role in the integration of sleep/wake and feeding behaviors in a broad spectrum of neural-metabolic physiology. Orexin-A and orexin-B are produced by the cleavage of prepro-orexin, which is encoded on the Hcrt gene.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57ff01928a27075eda4181b94f85b66
https://doi.org/10.1074/jbc.m113.455899
https://doi.org/10.1074/jbc.m113.455899
Publikováno v:
OBM Genetics. 2:1-1
Histone modifications play an important role in the control of all DNA-based processes by altering the structure and function of chromatin. An O-linked N-acetylglucosamine (O-GlcNAc) modification is a type of post-translational modification of protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31cc046fb53b4b0905d7d40e1a78b024
https://doi.org/10.21926/obm.genet.1803036
https://doi.org/10.21926/obm.genet.1803036
Publikováno v:
Cornea. 28:S7-S13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d831fa4eacf3b87344fe386ac6c4d2cd
https://doi.org/10.1097/ico.0b013e3181ae96bf
https://doi.org/10.1097/ico.0b013e3181ae96bf
Autor:
Kunio Shiota, Koji Hayakawa, Daisuke Arai, Takehiro Suzuki, Satoshi Tanaka, Mitsuko Hirosawa, Chikako Yoneda, Hitoshi Shiota, Naoshi Dohmae
Publikováno v:
Scientific Reports
We report here newly discovered O-linked-N-acetylglucosamine (O-GlcNAc) modification of histone H2A at Ser40 (H2AS40Gc). The mouse genome contains 18 H2A isoforms, of which 13 have Ser40 and the other five have Ala40. The combination of production of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f7806a8834a277e2178d2375d1ec6d9
https://pubmed.ncbi.nlm.nih.gov/27615797
https://pubmed.ncbi.nlm.nih.gov/27615797
Publikováno v:
Epigenetic Methods in Neuroscience Research ISBN: 9781493927531
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab1fc6997c2055fd7ea73a72973f8eee
https://doi.org/10.1007/978-1-4939-2754-8_3
https://doi.org/10.1007/978-1-4939-2754-8_3
Autor:
Rie Ito, Norihiro Sugino, Mitsuko Hirosawa, Rumiko Hayashi, Daisuke Arai, Yoshikazu Arai, Masakazu Horie, Fumio Kondo, Hiroyuki Nakazawa, Kunio Shiota, Shun Ichiro Izumi, Rie Ishii, Satoshi Takatori, Jun Ohgane, Tsunehisa Makino, Koji Hayakawa, Yusuke Iwasaki, Kazuhiko Akutsu, Koichi Saito
Publikováno v:
BioMed Research International, Vol 2015 (2015)
BioMed Research International
BioMed Research International
The regulation of transcription and genome stability by epigenetic systems are crucial for the proper development of mammalian embryos. Chemicals that disturb epigenetic systems are termed epimutagens. We previously performed chemical screening that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6409b9e8bceec95bcbf6aa48c57053
https://doaj.org/article/798b0ccbe40545b99cf98446cab4e7fb
https://doaj.org/article/798b0ccbe40545b99cf98446cab4e7fb
Autor:
Ulrich Schäfer, Herbert Jäckle, Julia K. Ulschmid, Katja Becker, Sebastian Grönke, Mitsuko Hirosawa-Takamori, John P. Phillips, Fanis Missirlis
Publikováno v:
Journal of Biological Chemistry
Defense against oxidative stress in mammals includes the regeneration of the major thiol reductants glutathione and thioredoxin by glutathione reductase and thioredoxin reductase (TrxR), respectively. In contrast, Drosophila, and possibly insects in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c401eb68fae5e63515d29bf0c7d7c106
https://doi.org/10.1074/jbc.m111692200
https://doi.org/10.1074/jbc.m111692200
Autor:
Mitsuko Hirosawa-Takamori, Susan Ferguson-Gottschall, Anne Prigent-Tessier, Catherine Boyer, Geula Gibori, Christian Tessier
Publikováno v:
Journal of Biological Chemistry. 274:37982-37989
Establishment and maintenance of pregnancy require the activity of a highly specialized maternal tissue, the decidua. It is well established that the human decidua synthesizes and releases prolactin. However, in the rat, no study has been able to dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f0815071ec7521bf308297aabe85ec8
https://doi.org/10.1074/jbc.274.53.37982
https://doi.org/10.1074/jbc.274.53.37982