Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mitsui Isobe"'
Publikováno v:
European Journal of Pharmacology. 779:168-176
Hepatic encephalopathy (HE) is a neuropsychiatric syndrome associated with hepatic dysfunction. However, the precise mechanism of HE is unclear. To elucidate the mechanism, we developed a new rat model of HE with coma using a combination of subcutane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c25cb370c9f04633bb10662f416b5aa0
https://doi.org/10.1016/j.ejphar.2016.03.024
https://doi.org/10.1016/j.ejphar.2016.03.024
Autor:
Jun Sato, Katsuhiko Ono, Sei ichi Araki, Motoko Fukui, Shuji Nagasaki, Yasuhiro Miki, Noriaki Nakashima, Hironobu Sasano, Mitsui Isobe, Satoko Asano, Kazuhiro Takahashi
Publikováno v:
Molecular and Cellular Endocrinology. 395:32-40
TSH is the important regulator of thyroid function but detailed molecular mechanisms have not been clarified. We first generated the iodine deficient (ID) rat in which goiter is induced by accelerated endogenous TSH secretion. The result of microarra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4cb084c1215a19fd162cb38dec562b4
https://doi.org/10.1016/j.mce.2014.07.008
https://doi.org/10.1016/j.mce.2014.07.008
Autor:
Shigeru Hisada, Norio Fukui, Shuji Nagasaki, Kuniyoshi Sakai, Mitsui Isobe, Yuko Hasegawa, Seiji Shibata, Motoko Fukui, Sei-ichi Araki
Publikováno v:
Journal of Toxicologic Pathology
The antithyroid drugs (ATDs) methimazole (MMI) and propylthiouracil (PTU) have been used for treatment of hyperthyroidism for more than several decades, despite the fact that they are associated with adverse drug reactions that are thought to be auto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e610408c4f87d6a9ca63c1b56105c2cc
http://europepmc.org/articles/PMC3921920
http://europepmc.org/articles/PMC3921920
Autor:
Kiyoko Ito, Kanako Takahashi, Minoru Suzuki, Toshi Horiuchi, Hisato Tanifuji, Mitsui Isobe, Shigeru Hisada, Kazuhiro Iizuka
Publikováno v:
Journal of Toxicologic Pathology. 8:25-32
The effect of ethinylestradiol (EE), a synthetic estrogen which is tumorigenic to the mammary gland, pituitary gland, and liver, on the cell proliferation in 5 organs was investigated in male rats. Cell proliferation was estimated by bromodeoxyuridin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::788375466841ec978c86631c121097f3
https://doi.org/10.1293/tox.8.25
https://doi.org/10.1293/tox.8.25
Publikováno v:
The Journal of Biochemistry. 99:1345-1352
Changes in peroxisomal CoA pools in the liver of fasted, diabetic, high-fat diet-fed and clofibrate-treated rats were studied. Total-CoA increased slightly in the fasted group and markedly in the diabetic, high-fat and clofibrate-treated groups. Frac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7e86c16267ba2e9e2d1036e5693cc02
https://doi.org/10.1093/oxfordjournals.jbchem.a135602
https://doi.org/10.1093/oxfordjournals.jbchem.a135602