Zobrazeno 1 - 2
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pro vyhledávání: '"Mitsuhito Shibasaki"'
Autor:
Leo A. Joyce, David E. Kaelin, Peter T. Meinke, Takeshi Shibata, Keith W. Rickert, Masaya Takei, Sangita B. Patel, Changqing Wei, Xiu Wang, Xuanjia Peng, David B. Olsen, Armando Lagrutta, Jun Lu, Masanobu Yajima, Yasumichi Fukuda, Jin Wu, Mitsuhito Shibasaki, Hideyuki Fukuda, Lynn Miesel, Christopher M. Tan, Stephen M. Soisson, Todd A. Black, Ryuta Kishii, Robert F. Smith, Ravi P. Nargund, Edward C. Sherer, Hisashi Takano, Sheo B. Singh, Akinori Nishimura
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:1831-1835
Novel bacterial topoisomerase inhibitors (NBTIs) represent a new class of broad-spectrum antibacterial agents targeting bacterial Gyrase A and ParC and have potential utility in combating antibiotic resistance. A series of novel oxabicyclooctane-link
Publikováno v:
HETEROCYCLES. 72:275
The cyclic peptide portion of chlorofusin was synthesized by condensation of the five segments, D-Ada-OTMSE, Boc-L-Orn(Cbz), Boc-L-Thr-L-Ala, L-Asn(Tr)-D-Asn(Tr)-D-Leu-OTMSE, and Boc-L-Thr-D-Leu, followed by cyclization at the amide bond between D-Ad