Zobrazeno 1 - 10
of 382
pro vyhledávání: '"Mitsuhiro YANAGIDA"'
Autor:
Ayaka Mori, Lisa Uehara, Yusuke Toyoda, Fumie Masuda, Saeko Soejima, Shigeaki Saitoh, Mitsuhiro Yanagida
Publikováno v:
Royal Society Open Science, Vol 10, Iss 10 (2023)
Mitochondria perform critical functions, including respiration, ATP production, small molecule metabolism, and anti-oxidation, and they are involved in a number of human diseases. While the mitochondrial genome contains a small number of protein-codi
Externí odkaz:
https://doaj.org/article/b28f5aed32334debbbcc30f602c4919c
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Definitive differences in blood metabolite profiles between obese and non-obese Type 2 diabetes (T2D) have not been established. We performed an LC–MS-based non-targeted metabolomic analysis of whole blood samples collected from subjects c
Externí odkaz:
https://doaj.org/article/1cf27595930f4be896008f015cc85f16
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Metabolites in human biofluids reflect individual physiological states influenced by various factors. Using liquid chromatography-mass spectrometry (LC–MS), we conducted non-targeted, non-invasive metabolomics using saliva of 27 healthy vo
Externí odkaz:
https://doaj.org/article/edea6e5599774a9a9122104cd53835b8
Publikováno v:
Open Biology, Vol 12, Iss 4 (2022)
Cohesin holds sister chromatids together and is cleaved by separase/Cut1 to release DNA during the transition from mitotic metaphase to anaphase. The cohesin complex consists of heterodimeric structural maintenance of chromosomes (SMC) subunits (Psm1
Externí odkaz:
https://doaj.org/article/8c6a4d638bd7487bb3d39b0725525494
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 8, Pp 2667-2676 (2019)
Genetically controlled mechanisms of cell division and quiescence are vital for responding to changes in the nutritional environment and for cell survival. Previously, we have characterized temperature-sensitive (ts) mutants of the cwh43 gene in fiss
Externí odkaz:
https://doaj.org/article/78671d87342d4ca499d76fea2885a2f1
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 6, Pp 1815-1823 (2019)
The mitotic kinetochore forms at the centromere for proper chromosome segregation. Deposition of the centromere-specific histone H3 variant, spCENP-A/Cnp1, is vital for the formation of centromere-specific chromatin and the Mis17-Mis6 complex of the
Externí odkaz:
https://doaj.org/article/f807d6019ec94e4b83b1d3e98e66d58b
Autor:
Xingya Xu, Mitsuhiro Yanagida
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 5, Pp 1777-1783 (2019)
Essential genes cannot be deleted from the genome; therefore, temperature-sensitive (ts) mutants and cold-sensitive (cs) mutants are very useful to discover functions of essential genes in model organisms such as Schizosaccharomyces pombe and Sacchar
Externí odkaz:
https://doaj.org/article/3339be5169d94127904b3d6539b4728b
Autor:
Lisa Uehara, Shigeaki Saitoh, Ayaka Mori, Kenichi Sajiki, Yusuke Toyoda, Fumie Masuda, Saeko Soejima, Yuria Tahara, Mitsuhiro Yanagida
Publikováno v:
Open Biology, Vol 11, Iss 4 (2021)
Mitochondria are essential for regulation of cellular respiration, energy production, small molecule metabolism, anti-oxidation and cell ageing, among other things. While the mitochondrial genome contains a small number of protein-coding genes, the g
Externí odkaz:
https://doaj.org/article/060ffc8df69840a6a3259f8373ea34d8
Publikováno v:
Open Biology, Vol 10, Iss 9 (2020)
Since ancient days, human fasting has been performed for religious or political reasons. More recently, fasting has been employed as an effective therapy for weight reduction by obese people, and numerous studies have investigated the physiology of f
Externí odkaz:
https://doaj.org/article/97e60ccf6af74d65b2e5fc9ad87a601b
Publikováno v:
iScience, Vol 5, Iss , Pp 38-51 (2018)
Summary: S-adenosylmethionine is an important compound, because it serves as the methyl donor in most methyl transfer reactions, including methylation of proteins, nucleic acids, and lipids. However, cellular defects in the genetic disruption of S-ad
Externí odkaz:
https://doaj.org/article/66915e0f4b2e444b950d0fd7b1d8e6ba