Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Mitsuhiro Hitotsuyanagi"'
Autor:
Takehiro Suzuki, Michinori Kohara, Takashi Imada, Naoshi Dohmae, Yo Ichi Tagawa, Koji Moriya, Mitsuhiro Hitotsuyanagi, Naoto Inukai, Masahiko Uchiyama, Daisuke Kiga, Shotaro Ayukawa, Akiko Masuda, Masayuki Yamamura
Publikováno v:
ACS Synthetic Biology. 7:2537-2546
Although conjugation with polyethylene glycol (PEGylation) improves the pharmacokinetics of therapeutic proteins, it drastically decreases their bioactivity. Site-specific PEGylation counters the reduction in bioactivity, but developing PEGylated pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d396c1f801a93a5fe168c43b757a1d8
https://doi.org/10.1021/acssynbio.8b00188
https://doi.org/10.1021/acssynbio.8b00188
Publikováno v:
Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life. 44(2)
At some stage of evolution, genes of organisms may have encoded proteins that were synthesized using fewer than 20 unique amino acids. Similar to evolution of the natural 19-amino-acid proteins GroEL/ES, proteins composed of 19 unique amino acids wou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b19561de21585b64c2998cdb32a252
https://pubmed.ncbi.nlm.nih.gov/25399308
https://pubmed.ncbi.nlm.nih.gov/25399308