Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Mitsuhiro Denda"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Olfactory receptors (ORs) are expressed in many tissues and have multiple functions. However, most studies have focused on individual ORs. Here, we aimed to conduct a comprehensive meta-transcriptome analysis of OR gene expression in human tissues by
Externí odkaz:
https://doaj.org/article/3d8064d12e2e4b7083bf9f875dacc0c4
Autor:
Kota Ohno, Yasuaki Kobayashi, Masaaki Uesaka, Takeshi Gotoda, Mitsuhiro Denda, Hideyuki Kosumi, Mika Watanabe, Ken Natsuga, Masaharu Nagayama
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The skin barrier is provided by the organized multi-layer structure of epidermal cells, which is dynamically maintained by a continuous supply of cells from the basal layer. The epidermal homeostasis can be disrupted by various skin diseases
Externí odkaz:
https://doaj.org/article/fca2817c82154f88bad860b0c2500169
Autor:
Yuina Abe, Hajime Konno, Shotaro Yoshida, Takeshi Yamauchi, Kenshi Yamasaki, Mitsuhiro Denda, Matsuhiko Nishizawa
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219198 (2019)
The light-promoted recovery of epidermal barrier of skin was evaluated by the associated recovery of transepidermal potential (TEP), the potential difference between the surface and dermis of skin, by using porcine skin samples. An accelerated recove
Externí odkaz:
https://doaj.org/article/02757a727f624109876ed950e64fe33a
Autor:
Mitsuhiro Denda
Publikováno v:
Dermatologica Sinica, Vol 33, Iss 2, Pp 70-73 (2015)
The role of the brain includes reception, processing, and transmission of environmental information from sensory organs to the systems of the whole body. Interestingly, the digestive organs have an independent nervous system, which has been called th
Externí odkaz:
https://doaj.org/article/7ff44e65a27b4a45bacfde052c3bdc16
Autor:
Yasuaki Kobayashi, Yumi Sanno, Akihiko Sakai, Yusuke Sawabu, Moe Tsutsumi, Makiko Goto, Hiroyuki Kitahata, Satoshi Nakata, Junichi Kumamoto, Mitsuhiro Denda, Masaharu Nagayama
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92650 (2014)
Recent studies have shown that the behavior of calcium in the epidermis is closely related to the conditions of the skin, especially the differentiation of the epidermal keratinocytes and the permeability barrier function, and therefore a correct und
Externí odkaz:
https://doaj.org/article/16b193613acd47a2b78b0028ea0401ff
Publikováno v:
Biochemical and Biophysical Research Communications. 548:1-6
Malodorous compounds induce stress responses, mood changes, an increase of skin conductance, activation of the sympathetic nervous system and other physiological changes, and it has been suggested that sensing malodors could provide warning of danger
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::214af9982cab4503efee7c38f5c9a3c0
https://doi.org/10.1016/j.bbrc.2021.02.050
https://doi.org/10.1016/j.bbrc.2021.02.050
Publikováno v:
Biological and Pharmaceutical Bulletin. 43:1591-1594
Japanese cedar (Cryptomeria japonica) pollen allergen Cry j1 increases the intracellular calcium concentration in human keratinocytes, and also impairs the epidermal barrier function. Here, we show that reduced glutathione (GSH) blocks both thrombin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b2f19b781a1fa72cb6d8a944c3454ee
https://doi.org/10.1248/bpb.b20-00264
https://doi.org/10.1248/bpb.b20-00264
Publikováno v:
Experimental Dermatology. 29:393-399
Improvement of the water-impermeable barrier function of skin is clinically important, because barrier abnormality is associated with various skin diseases, such as psoriasis or atopic dermatitis. We have shown that topical application of fatty acids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1279118af03fcd62867b3c691166a5a
https://doi.org/10.1111/exd.14075
https://doi.org/10.1111/exd.14075
Autor:
Mitsuhiro Denda, Shinobu Nakanishi
Publikováno v:
Advances in Anthropology. 10:17-32
Among terrestrial mammals, Homo sapiens has evolved a very specific anatomical feature—very little body hair—thus, the skin surface is exposed directly to the environment. We and others have demonstrated that skin epithelial cells, called keratin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bef76720f1c9ac7a7710c6325b7aed0
https://doi.org/10.4236/aa.2020.101002
https://doi.org/10.4236/aa.2020.101002
Autor:
Shinobu Nakanishi, Mitsuhiro Denda
Publikováno v:
Experimental dermatologyREFERENCES. 31(4)
It was long considered that the role of epidermal keratinocytes is solely to construct a water-impermeable protective membrane, the stratum corneum, at the uppermost layer of the skin. However, in the last two decades, it has been found that keratino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::750b270bbf5e7890620d36d16c5683b1
https://pubmed.ncbi.nlm.nih.gov/34726302
https://pubmed.ncbi.nlm.nih.gov/34726302