Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mitsuhiko Kawabata"'
Autor:
Yuchen Sun, Shin-ichiro Nitta, Kosuke Saito, Ryuta Hosogai, Keiko Nakai, Ryoya Goda, Hisao Shimizu, Hisashi Fujita, Masaaki Kakehi, Kazuyuki Murata, Takeru Yamaguchi, Takeshi Okuzono, Shinichi Yamane, Mitsuhiko Kawabata, Takayuki Matsunuma, Kentaro Takahara, Noriko Kato, Masaki Yamada, Tokuyuki Yoshida, Takao Inoue, Yoshiro Saito
Publikováno v:
Bioanalysis. 14(18)
Background: Many bioanalytical methods for antisense oligonucleotides (ASOs) using LC–MS have been reported. However, no data have been available on the reproducibility and robustness of a single bioanalytical method for ASOs. As such, in the curre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e05130eab8441e7d0a6a649cd46a4ec4
https://pubmed.ncbi.nlm.nih.gov/36408704
https://pubmed.ncbi.nlm.nih.gov/36408704
Autor:
Noriko Inoue, Takuma Shigeyama, Hidehisa Tachiki, Takeru Yamaguchi, Kazuyuki Murata, Koji Arai, Shinichi Yamane, Mitsuhiko Kawabata, Mariko Yamaoka, Mio Nakatsuji, Takeshi Okuzono, Noritaka Hashii, Yoshiro Saito, Suguru Fukuda, Akiko Ishii-Watabe, Yoshimasa Enoki, Yoshiko Tousaka, Ryoya Goda
Publikováno v:
Bioanalysis. 13:265-276
Aim: We aimed to develop an easy, low-cost and versatile mass spectrometric method for the bioanalysis of a therapeutic monoclonal antibody (mAb) in human serum that employs peptide adsorption-controlled (PAC)-LC/MS using selected reaction monitoring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7483edd55a6f33ee464b8c4230b0fbec
https://doi.org/10.4155/bio-2020-0262
https://doi.org/10.4155/bio-2020-0262
Autor:
Tsuyoshi Matsumura, Kota Asahina, Mariko Yamaoka, Mitsuhiko Kawabata, Rika Ishikawa, Saki Yamauchi, Takahiro Suga, Shin-Ichiro Nitta, Akemi Nagao, Yoshiro Saito, Hitoshi Uchiyama, Keiko Nakai, Koji Arai, Ryoya Goda, Kosuke Saito, Hidehisa Tachiki
Publikováno v:
Bioanalysis. 13(20)
Aim: Although the fit-for-purpose approach has been proposed for validation procedures and acceptance criteria for biomarker assays, practical biomarker assays to facilitate clinical application and regulatory documents on biomarker assays remain lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4497f490959435aaef1d563bf40838a8
https://pubmed.ncbi.nlm.nih.gov/34696608
https://pubmed.ncbi.nlm.nih.gov/34696608
Autor:
Hiroyuki Sasabe, Yosuke Kaneko, Masayuki Furukawa, Masayuki Matsunaga, Eiji Kashiyama, Yukihiro Hirao, Mitsuhiko Kawabata, Noriyuki Koyama, Toshihisa Koga, Hitomi Akazawa, Kenji Takeuchi
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 51(5)
The pharmacokinetics of brexpiprazole were investigated in the in vitro and in vivo.The total body clearance of brexpiprazole in rat and monkey was 2.32 and 0.326 L/h/kg, respectively, after intrav...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab7762bcff7a84c2ea001970b465d606
https://pubmed.ncbi.nlm.nih.gov/33685346
https://pubmed.ncbi.nlm.nih.gov/33685346
Autor:
Takashi Matsuyama, Mutsuko Hirata-Koizumi, Akihiko Hirose, Mitsuhiko Kawabata, Kiyomi Matsuno, Eiichi Kamata, Kanako Yajima, Makoto Ema
Publikováno v:
Drug and Chemical Toxicology. 32:204-214
Previously, we showed that the toxic susceptibility of male rats to an ultraviolet absorber, 2-(2'-hydroxy- 3',5'-di-tert-butylphenyl)benzotriazole (HDBB), was nearly 25 times higher than that of females. The present study aimed to clarify the mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f33888b202bb1dfbbf0dcd60c17e817
https://doi.org/10.1080/01480540902862244
https://doi.org/10.1080/01480540902862244
Autor:
Hitoshi Tanikawa, Masakazu Yamazaki, Osami Ito, Atsushi Takai, Koichi Kuroki, Osamu Murakami, Mitsuhiko Kawabata
Publikováno v:
SAE Technical Paper Series.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddc5aa3964b93bcb36b813de88ec2599
https://doi.org/10.4271/2004-01-1447
https://doi.org/10.4271/2004-01-1447
Autor:
Mitsuhiko Kawabata, Kazumi Ishidoh, Koji Tomoo, Kazumasa Satoh, Tetsuya Ogino, Eiki Kominami, Hiroshi Yamazaki, Toshio Kaji, Toshimasa Ishida
Publikováno v:
Journal of biochemistry. 126(1)
In order to determine the functional role of the procathepsin L propeptide region for the preparation of active recombinant rat cathepsin L (CL), cDNAs encoding two short-length propeptides (C-terminal 2 and 27 residues) and the full-length (96 resid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e737b128ba38de5a608ea616ad80580
https://pubmed.ncbi.nlm.nih.gov/10393323
https://pubmed.ncbi.nlm.nih.gov/10393323
Autor:
Sasabe, Hiroyuki1 (AUTHOR), Koga, Toshihisa1 (AUTHOR), Furukawa, Masayuki1 (AUTHOR), Matsunaga, Masayuki1 (AUTHOR), Kaneko, Yosuke1 (AUTHOR), Koyama, Noriyuki1 (AUTHOR), Hirao, Yukihiro1 (AUTHOR), Akazawa, Hitomi2 (AUTHOR), Kawabata, Mitsuhiko3 (AUTHOR), Kashiyama, Eiji1 (AUTHOR), Takeuchi, Kenji1 (AUTHOR)
Publikováno v:
Xenobiotica. May2021, Vol. 51 Issue 5, p590-604. 15p.
Autor:
Hirata-Koizumi, Mutsuko1 (AUTHOR) mkoizumi@nihs.go.jp, Matsuno, Kiyomi2 (AUTHOR), Kawabata, Mitsuhiko2 (AUTHOR), Yajima, Kanako2 (AUTHOR), Matsuyama, Takashi2 (AUTHOR), Hirose, Akihiko1 (AUTHOR), Kamata, Eiichi1 (AUTHOR), Ema, Makoto1 (AUTHOR)
Publikováno v:
Drug & Chemical Toxicology. Jul2009, Vol. 32 Issue 3, p204-214. 11p. 2 Charts, 4 Graphs.
Autor:
Ogino, Tetsuya1, Kaji, Toshio1, Kawabata, Mitsuhiko1, Satoh, Kazumasa1, Tomoo, Koji1, Ishida, Toshimasa1, Yamazaki, Hiroshi2, Ishidoh, Kazumi3, Kominami, Eiki3
Publikováno v:
Journal of Biochemistry. 1999, Vol. 126 Issue 1, p78-83. 6p.