Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Mitsuhiko, Sugimoto"'
Autor:
Masashi Noda, Kohei Tatsumi, Hideto Matsui, Yasunori Matsunari, Takeshi Sato, Yasushi Fukuoka, Akitsu Hotta, Teruo Okano, Kimihiko Kichikawa, Mitsuhiko Sugimoto, Midori Shima, Kenji Nishio
Publikováno v:
Regenerative Therapy, Vol 18, Iss , Pp 347-354 (2021)
Introduction: Gene therapy have recently attracted much attention as a curative therapeutic option for inherited single gene disorders such as hemophilia. Hemophilia is a hereditary bleeding disorder caused by the deficiency of clotting activity of f
Externí odkaz:
https://doaj.org/article/a3e5595250fe4d9daf624a5260659797
Autor:
Shiro Ono, Hideto Matsui, Masashi Noda, Shogo Kasuda, Noritaka Yada, Kiyomi Yoshimoto, Masashi Akiyama, Toshiyuki Miyata, Mitsuhiko Sugimoto, Kenji Nishio
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Abstract Acute kidney injury (AKI), an abrupt loss of renal function, is often seen in clinical settings and may become fatal. In addition to its hemostatic functions, von Willebrand factor (VWF) is known to play a role in cross-talk between inflamma
Externí odkaz:
https://doaj.org/article/580ebd31650b431a94c0d6f312e0a87b
Autor:
Akihiro Sawa, Kohei Tatsumi, Yoko Takabayashi, Yu Onodera, Ayaka Kakiwaki, Satoshi Senzaki, Nobushiro Nishimura, Hiromasa Kawashima, Kiyomi Yoshimoto, Mitsuhiko Sugimoto, Midori Shima, Kenji Nishio
Publikováno v:
Blood. 140:5516-5517
Autor:
Shogo Kasuda, Hideto Matsui, Shiro Ono, Yasunori Matsunari, Kenji Nishio, Midori Shima, Katsuhiko Hatake, Mitsuhiko Sugimoto
Publikováno v:
Haematologica, Vol 101, Iss 2 (2016)
Externí odkaz:
https://doaj.org/article/dfcb2eec6dfb4bcbbd0eccdc30f688f5
Autor:
Hideto Matsui, Maiko Takeda, Kenji Soejima, Yasunori Matsunari, Shogo Kasuda, Shiro Ono, Kenji Nishio, Midori Shima, Fumiaki Banno, Toshiyuki Miyata, Mitsuhiko Sugimoto
Publikováno v:
Haematologica, Vol 99, Iss 10 (2014)
Externí odkaz:
https://doaj.org/article/5515a8ecb9434eaba80c150a3d7cabbe
Autor:
Hideto Matsui, Naoko Fujimoto, Noriko Sasakawa, Yasuhide Ohinata, Midori Shima, Shinya Yamanaka, Mitsuhiko Sugimoto, Akitsu Hotta
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104957 (2014)
Viral vectors have been used for hemophilia A gene therapy. However, due to its large size, full-length Factor VIII (FVIII) cDNA has not been successfully delivered using conventional viral vectors. Moreover, viral vectors may pose safety risks, e.g.
Externí odkaz:
https://doaj.org/article/d34c366589754fad98ba278a41c0b6c9
Autor:
Kohei Tatsumi, Mitsuhiko Sugimoto, David Lillicrap, Midori Shima, Kazuo Ohashi, Teruo Okano, Hideto Matsui
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83280 (2013)
Gene- or cell-based therapies aimed at creating delivery systems for coagulation factor VIII (FVIII) protein have emerged as promising options for hemophilia A treatment. However, several issues remain to be addressed regarding the efficacies and adv
Externí odkaz:
https://doaj.org/article/6f4e401cb367400fae31629a25bc4a5a
Autor:
Hideto Matsui, Asuka Sakata, Masashi Akiyama, Masayuki Sho, Toshiyuki Miyata, Kiyomi Yoshimoto, Kenji Nishio, Kazuo Okuchi, Mitsuhiko Sugimoto, Shiro Ono, Satoshi Nishimura, Shogo Kasuda, Yasuyuki Urisono
Publikováno v:
Thrombosis and Haemostasis. 47:700-708
Hepatic ischaemia–reperfusion (I/R) injury is a serious liver damage that critically influences the clinical outcome of liver surgery or transplantation. Since recent studies indicated the critical involvement of von Willebrand factor (VWF) in repe
Autor:
Yasuaki Shida, Yoshihiro Fujimura, Hideo Yagi, Naoko Yamaguchi, Kazuo Tubaki, Masanori Matsumoto, Mitsuhiko Sugimoto
Publikováno v:
Thrombosis Research. 159:91-95
Upshaw-Schulman syndrome (USS) is a thrombo-hemorrhagic disease caused by congenital deficiency of ADAMTS13 due to ADAMTS13 gene mutations. USS is characterized by repeated episodes of thrombocytopenia and microangiopathic hemolytic anemia that respo
Autor:
Noritaka Yada, Shiro Ono, Masashi Noda, Mitsuhiko Sugimoto, Kenji Nishio, Shogo Kasuda, Hideto Matsui, Toshiyuki Miyata, Masashi Akiyama, Kiyomi Yoshimoto
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports
Scientific Reports
Acute kidney injury (AKI), an abrupt loss of renal function, is often seen in clinical settings and may become fatal. In addition to its hemostatic functions, von Willebrand factor (VWF) is known to play a role in cross-talk between inflammation and