Výsledky vyhledávání - "Mitsugu Fukuda"

Autor: Yohko Takagi, Nobuko Shimada, Yasushi Ishijima, Naoshi Ishikawa, Narimichi Kimura, Mitsugu Fukuda

Publikováno v: Journal of Bioenergetics and Biomembranes. 35:7-18

Genomic data regarding the nucleoside diphosphate (NDP) kinase genes have been accumulated from diverged phyla. Comparison of their regulatory sequences have shed light on the multiple facets of gene regulation systems. Phylogenetic studies, includin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::137ca238e9d7f834e012851423ee5c00
https://doi.org/10.1023/a:1023433504713

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Autor: Yasushi Ishijima, Mitsugu Fukuda, Naoshi Ishikawa, Nobuko Shimada, Narimichi Kimura, Yohko Takagi

Publikováno v: Journal of Bioenergetics and Biomembranes. 35:41-47

The role of nucleoside diphosphate (NDP) kinase with special reference to mammalian signal transduction systems was described. The interaction between NDP kinases and G proteins was reevaluated in view of their protein structural information and its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::29ec12d63e291e3f12de6c126404dd4a
https://doi.org/10.1023/a:1023489722460

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Autor: Yasushi Ishijima, Mitsugu Fukuda, Narimichi Kimura, Akio Ishii, Naoshi Ishikawa, Nobuko Shimada, Yohko Takagi, Hidetaka Miyazaki

Publikováno v: Journal of Bioenergetics and Biomembranes. 32:309-315

The role of nucleoside diphosphate (NDP) kinases in cell growth, differentiation, and tumormetastasis in relation to signal transduction was investigated. The essential role of NDP kinasein cell growth was validated by coupling between reduced NDP ki

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d6de4270c25269f7b600443d9a8af65
https://doi.org/10.1023/a:1005549315846

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A biotinylated perfringolysin O derivative: A new probe for detection of cell surface cholesterol

Autor: Ikuo Morita, Yoshiko Ohno-Iwashita, Mitsugu Fukuda, Sei-itsu Murota, Susumu Ando, Machiko Iwamoto

Publikováno v: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1327:222-230

theta-Toxin is a cholesterol-binding, pore-forming cytolysin of Clostridium perfringens. To detect cell surface cholesterol, we prepared a theta-toxin derivative, BC theta by biotinylation of a protease-nicked theta-toxin, which has the same binding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b2f60a2ed6fca8ab0b6a468c6da05e2
https://doi.org/10.1016/s0005-2736(97)00061-8

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Decreased expression of nucleoside diphosphate kinase α isoform, annm23-H2 gene homolog, is associated with metastatic potential of rat mammary-adenocarcinoma cells

Autor: Tatsuro Irimura, Akio Ishii, Naokazu Nagata, Mitsugu Fukuda, Garth L. Nicolson, Naoshi Ishikawa, Yoshiro Yasutomo, Nobuko Shimada, Narimichi Kimura, Nobuo Hanai

Publikováno v: International Journal of Cancer. 65:531-537

The nm23 gene [encoding nucleoside diphosphate kinase (NDPK)] may act as a metastasis suppressor in certain tumor cells. We investigated the role of NDPK isoforms (alpha and beta) in the metastatic processes, using rat mammary-adenocarcinoma cell lin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f3d28d7d616d0e252713b3bb4aeba053
https://doi.org/10.1002/(sici)1097-0215(19960208)65:4<531::aid-ijc23>3.0.co

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Developmental and age-related changes of peptidylarginine deiminase 2 in the mouse brain

Autor: Jaewon Lee, Nobuko Shimada, Setsuko Handa, Hiroaki Asaga, Mitsugu Fukuda, Akihito Ishigami, Yoshiaki Uchida, Eun-Kyoung Choi, Naoki Maruyama

Publikováno v: Journal of neuroscience research. 88(4)

Peptidylarginine deiminases (PADs) are a group of posttranslational modification enzymes that citrullinate (deiminate) protein arginine residues in a Ca(2+)-dependent manner. Enzymatic citrullination abolishes positive charges of native protein molec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40104942cbdb46a7574b13acf517befa
https://pubmed.ncbi.nlm.nih.gov/19830834

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Elevated levels of 4-hydroxynonenal-histidine Michael adduct in the hippocampi of patients with Alzheimer's disease

Autor: Fumihisa Kanou, Akihito Ishigami, Nobuko Shimada, Masakatsu Hashimoto, Yuko Saito, Mitsugu Fukuda, Naoki Maruyama, Motoji Sawabe, Shigeo Murayama

Publikováno v: Biomedical research (Tokyo, Japan). 30(4)

Alzheimer's disease (AD) is among the most common causes of progressive cognitive impairment in humans and is characterized by neurodegeneration in the brain. Lipid peroxidation is thought to play a role in the pathogenesis of AD. 4-hydroxynonenal (H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a42cefdc59aeb3f0f9a561509ccb763
https://pubmed.ncbi.nlm.nih.gov/19729853

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Vitamin C depletion increases superoxide generation in brains of SMP30/GNL knockout mice

Autor: Yoshitaka Kondo, Yasunori Sato, Akihito Ishigami, Kyu-Shik Jeong, Toru Sasaki, Setsuko Handa, Shingo Aizawa, Mizuki Iwama, Naoki Maruyama, Mitsugu Fukuda, Nobuko Shimada, Jaewon Lee, Masumi Akita, Akiko Amano

Publikováno v: Biochemical and biophysical research communications. 377(1)

Vitamin C (VC) has a strong antioxidant function evident as its ability to scavenge superoxide radicals in vitro. We verified that this property actually exists in vivo by using a real-time imaging system in which Lucigenin is the chemiluminescent pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee04b9163a346e5dfa4a64d3e5ff7c90
https://pubmed.ncbi.nlm.nih.gov/18848523

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Molecular evolution of nucleoside diphosphate kinase genes: conserved core structures and multiple-layered regulatory regions

Autor: Naoshi, Ishikawa, Nobuko, Shimada, Yohko, Takagi, Yasushi, Ishijima, Mitsugu, Fukuda, Narimichi, Kimura

Publikováno v: Journal of bioenergetics and biomembranes. 35(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::29363b7358e58677671408be85130784
https://pubmed.ncbi.nlm.nih.gov/12848336

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Differences in DNA synthesis in vitro using isolated nuclei from regenerating livers of young and aged rats

Autor: Takahiko Taguchi, Mochihiko Ohashi, Mitsugu Fukuda

Publikováno v: Mechanisms of ageing and development. 122(2)

To detect changes in DNA synthesis during ageing, we compare DNA synthesis in the livers of young and aged rats. As an intermediate between an in vivo system using intact cells and an in vitro system using purified DNA polymerases, isolated nuclei we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e2395d750fbeb70571171f6a12e95e
https://pubmed.ncbi.nlm.nih.gov/11166354

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