Play stimulation as a possible means to buffer early stress from commercial hatchery treatment in laying hen chicks

Autor: Van Poucke, Enya, Mitschler, Perrine, Jensen, Per

Publikováno v: In Applied Animal Behaviour Science May 2024 274

Design, synthesis, structure-activity relationships and X-ray structural studies of novel 1-oxopyrimido[4,5-c]quinoline-2-acetic acid derivatives as selective and potent inhibitors of human aldose reductase

Autor: Crespo, Isidro, Giménez-Dejoz, Joan, Porté, Sergio, Cousido-Siah, Alexandra, Mitschler, André, Podjarny, Alberto, Pratsinis, Harris, Kletsas, Dimitris, Parés, Xavier, Ruiz, Francesc X., Metwally, Kamel, Farrés, Jaume

Publikováno v: In European Journal of Medicinal Chemistry 25 May 2018 152:160-174

Enantiomer Discrimination Illustrated by High-Resolution Crystal Structures of the Human Nuclear Receptor hRARγ

Autor: Klaholz, Bruno P., Mitschler, Andre, Belema, Makonen, Zusi, C., Moras, Dino

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2000 Jun 01. 97(12), 6322-6327.

Externí odkaz: https://www.jstor.org/stable/122635

High-resolution neutron and X-ray diffraction room-temperature studies of an H-FABP–oleic acid complex: study of the internal water cluster and ligand binding by a transferred multipolar electron-density distribution

Autor: E. I. Howard, B. Guillot, M. P. Blakeley, M. Haertlein, M. Moulin, A. Mitschler, A. Cousido-Siah, F. Fadel, W. M. Valsecchi, Takashi Tomizaki, T. Petrova, J. Claudot, A. Podjarny

Publikováno v: IUCrJ, Vol 3, Iss 2, Pp 115-126 (2016)

Crystal diffraction data of heart fatty acid binding protein (H-FABP) in complex with oleic acid were measured at room temperature with high-resolution X-ray and neutron protein crystallography (0.98 and 1.90 Å resolution, respectively). These data

Externí odkaz: https://doaj.org/article/bf03bda19f924cbeaba538d74a54fb78

Conformational editing of intrinsically disordered protein by α-methylation

Autor: Valentin Bauer, Yves Nominé, Natacha Rochel, Jozica Dolenc, Gergő Gógl, Vladimir Yu. Torbeev, Gilles Travé, Andre Mitschler, Boris Schmidtgall, Judit Osz, Alexandra Cousido-Siah, Camille Kostmann, Bruno Kieffer

Publikováno v: Chemical Science
Chemical Science, The Royal Society of Chemistry, 2021, 12 (3), pp.1080-1089. ⟨10.1039/d0sc04482b⟩
Chemical Science, 2021, 12 (3), pp.1080-1089. ⟨10.1039/D0SC04482B⟩
Chemical Science, 12 (3)

Intrinsically disordered proteins (IDPs) constitute a large portion of “Dark Proteome” – difficult to characterize or yet to be discovered protein structures. Here we used conformationally constrained α-methylated amino acids to bias the confo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d6d58921d1aed4d1ea9ab820be41c3d
https://doi.org/10.1039/d0sc04482b