Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mitra Zarifi Khosroshahi"'
Autor:
Atziri Corin Chavez Alvarez, Chahrazed Bouzriba, Emmanuel Moreau, Philippe Auzeloux, Sophie Besse, Vincent Ouellette, Mitra Zarifi Khosroshahi, Marie-France Côté, Sylvie Pilote, Elisabeth Miot-Noirault, Jean-Michel Chezal, Chantale Simard, René C -Gaudreault, Sébastien Fortin
Publikováno v:
Journal of Medicinal Chemistry. 66:2477-2497
Autor:
Mathieu Gagné-Boulet, Mitra Zarifi Khosroshahi, Stéphane Gobeil, Sébastien Fortin, Atziri Corin Chavez Alvarez, René C.-Gaudreault
Publikováno v:
The Journal of pharmacy and pharmacologyReferences. 72(2)
Objectives In this study, the antiproliferative activity of 3 phenyl 4-(2-oxo-3-alkylimidazolidin-1-yl)benzenesulfonates (PAIB-SOs) was assessed in a time-dependent manner together with their hepatic stability and metabolism using human, mouse and ra
Autor:
Mathieu Gagné-Boulet, Marie-France Côté, Atziri Corin Chavez Alvarez, Sébastien Fortin, Mitra Zarifi Khosroshahi
Publikováno v:
Bioorganicmedicinal chemistry. 26(18)
The role and the importance of the sulfonate moiety in phenyl 4-(2-oxo-3-alkylimidazolidin-1-yl)benzenesulfonates (PAIB-SOs) were assessed using its bioisosteric sulfonamide equivalent leading to new cytochrome P450 1A1 (CYP1A1)-activated prodrugs de