Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Mitra Shourian"'
Autor:
Mitra Shourian, Salman T. Qureshi
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Cryptococcus neoformans is a ubiquitous environmental yeast and a leading cause of invasive fungal infection in humans. The most recent estimate of global disease burden includes over 200,000 cases of cryptococcal meningitis each year. Cryptococcus n
Externí odkaz:
https://doaj.org/article/ed265e33face4a5cb979886da7603c3f
Publikováno v:
Frontiers in Immunology, Vol 8 (2018)
Interleukin-1 alpha (IL-1α) and interleukin-1 beta (IL-1β) are pro-inflammatory cytokines that are induced after Cryptococcus neoformans infection and activate the interleukin-1 receptor type I (IL-1RI). To establish the role of IL-1RI signaling in
Externí odkaz:
https://doaj.org/article/0197519355c843eba206db935b728a37
Autor:
Mitra Shourian, Salman T. Qureshi, Jörg H. Fritz, Roman Istomine, Tho Al-Fakar Al-Aubodah, Fernando Alvarez, Nils Pavey, Ciriaco A. Piccirillo
Publikováno v:
Mucosal Immunology. 12:746-760
CD4+Foxp3+ regulatory T (TREG) cells are critical mediators of peripheral tolerance and modulators of immune responses. Functional adaptation of TREG cells, through acquisition of secondary transcription factors is critical for their effector differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c6187d353822b2489b06181d9f7af7b
https://doi.org/10.1038/s41385-019-0153-5
https://doi.org/10.1038/s41385-019-0153-5
Publikováno v:
Seminars in immunology. 42
Overcoming exhaustion-associated dysfunctions and generating antigen-specific CD8 T cells with the ability to persist in the host and mediate effective long-term anti-tumor immunity is the final aim of cancer immunotherapy. To achieve this goal, immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d2a08c00c19fb6faef1cad411fed505
https://pubmed.ncbi.nlm.nih.gov/31604532
https://pubmed.ncbi.nlm.nih.gov/31604532
Publikováno v:
The Journal of Immunology. 206:58.06-58.06
T-cell exhaustion and reduced memory potential is an obstacle to successful adoptive cell therapy (ACT) of cancer. Ex-vivo expansion protocols require sustained TCR and cytokine stimulation that limit ACT efficacy and long-term persistence. We have s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec8dc3f0ad3ced8192ca241349bc0f6a
https://doi.org/10.4049/jimmunol.206.supp.58.06
https://doi.org/10.4049/jimmunol.206.supp.58.06
Publikováno v:
The Journal of Immunology. 206:58.07-58.07
Immune checkpoint (IC) blockade has revolutionized the treatment of chemo-refractory solid tumors and has demonstrated promising results for the treatment of resistant blood cancers, including lymphoma. However, clinical response to PD1 blockade depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1803c62f49a3e016cda3d50775ea791
https://doi.org/10.4049/jimmunol.206.supp.58.07
https://doi.org/10.4049/jimmunol.206.supp.58.07
Autor:
Fernando, Alvarez, Roman, Istomine, Mitra, Shourian, Nils, Pavey, Tho Al-Fakar, Al-Aubodah, Salman, Qureshi, Jörg H, Fritz, Ciriaco A, Piccirillo
Publikováno v:
Mucosal immunology. 12(3)
CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3caeddb224a0266cd6043184144eb5f2
https://pubmed.ncbi.nlm.nih.gov/30872761
https://pubmed.ncbi.nlm.nih.gov/30872761
Publikováno v:
Frontiers in Immunology
Interleukin-1 alpha (IL-1α) and interleukin-1 beta (IL-1β) are pro-inflammatory cytokines that are induced after Cryptococcus neoformans infection and activate the interleukin-1 receptor type I (IL-1RI). To establish the role of IL-1RI signaling in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::99b092ae7453e39bd6338488f4832345
https://pubmed.ncbi.nlm.nih.gov/29403476
https://pubmed.ncbi.nlm.nih.gov/29403476
Publikováno v:
Blood. 134:2806-2806
Background: Immune checkpoint (IC) blockade has revolutionized the treatment of chemo-refractory solid tumors and has demonstrated promising results for the treatment of resistant blood cancers, including lymphoma. However, clinical response to PD1 b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a3501900c1a87678ff526ad191a8710
https://doi.org/10.1182/blood-2019-130647
https://doi.org/10.1182/blood-2019-130647
Autor:
Arnold S. Kristof, Sabah N. A. Hussain, Alexandra Triantafillopoulos, Mitra Shourian, Scott F. Carroll, Anders Bondo Dydensborg, Sharon Harel, Jill A. Fielhaber, Maxime Bouchard, Salman T. Qureshi
Publikováno v:
The Journal of Immunology. 188:4535-4542
Acute lung injury during bacterial infection is associated with neutrophilic inflammation, epithelial cell apoptosis, and disruption of the alveolar-capillary barrier. TLR4 is required for lung injury in animals exposed to bacterial LPS and initiates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8efb1d256cab20236f09ef42112af50
https://doi.org/10.4049/jimmunol.1003655
https://doi.org/10.4049/jimmunol.1003655