Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Mitra S Rana"'
Autor:
Carlos M. Guardia, Xiao-Feng Tan, Tengfei Lian, Mitra S. Rana, Wenchang Zhou, Eric T. Christenson, Augustus J. Lowry, José D. Faraldo-Gómez, Juan S. Bonifacino, Jiansen Jiang, Anirban Banerjee
Publikováno v:
Cell Reports, Vol 31, Iss 13, Pp 107837- (2020)
Summary: Autophagy is a catabolic process involving capture of cytoplasmic materials into double-membraned autophagosomes that subsequently fuse with lysosomes for degradation of the materials by lysosomal hydrolases. One of the least understood comp
Externí odkaz:
https://doaj.org/article/c2bbdec4aa9f4899827cc7fabd64a7b9
Autor:
Chul-Jin Lee, Robyn Stix, Mitra S. Rana, Flowreen Shikwana, R. Elliot Murphy, Rodolfo Ghirlando, José D. Faraldo-Gómez, Anirban Banerjee
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(7)
S-acylation, also known as palmitoylation, is the most abundant form of protein lipidation in humans. This reversible posttranslational modification, which targets thousands of proteins, is catalyzed by 23 members of the DHHC family of integral membr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dafa568d194a3a1fdeca07dd8d1f0d1
https://pubmed.ncbi.nlm.nih.gov/35140179
https://pubmed.ncbi.nlm.nih.gov/35140179
Publikováno v:
Biochemical Society Transactions. 47:157-167
Protein S-acylation is a reversible lipidic posttranslational modification where a fatty acid chain is covalently linked to cysteine residues by a thioester linkage. A family of integral membrane enzymes known as DHHC protein acyltransferases (DHHC-P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54659b34b21ca25a248a6c7142768c60
https://doi.org/10.1042/bst20180429
https://doi.org/10.1042/bst20180429
Autor:
Constance Baer, Shunsuke Kimura, Mitra S. Rana, Andrew B. Kleist, Tim Flerlage, David J. Feith, Peter Chockley, Wencke Walter, Manja Meggendorfer, Thomas L. Olson, HeeJin Cheon, Kristine C. Olson, Aakrosh Ratan, Martha-Lena Mueller, James M. Foran, Laura J. Janke, Chunxu Qu, Shaina N. Porter, Shondra M. Pruett-Miller, Ravi C. Kalathur, Claudia Haferlach, Wolfgang Kern, Elisabeth Paietta, Paul G. Thomas, M. Madan Babu, Thomas P. Loughran, Ilaria Iacobucci, Torsten Haferlach, Charles G. Mullighan
Publikováno v:
Nature genetics. 54(5)
Chronic lymphoproliferative disorder of natural killer cells (CLPD-NK) is characterized by clonal expansion of natural killer (NK) cells where the underlying genetic mechanisms are incompletely understood. In the present study, we report somatic muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228c0878716efff5e6e286513d8566d4
https://pubmed.ncbi.nlm.nih.gov/35513723
https://pubmed.ncbi.nlm.nih.gov/35513723
Autor:
James M. Foran, Mitra S Rana, Andrew B. Kleist, Martha-Lena Mueller, Claudia Haferlach, David J. Feith, Ravi C. Kalathur, Thomas P. Loughran, Manja Meggendorfer, Aakrosh Ratan, Ilaria Iacobucci, Thomas L. Olson, HeeJin Cheon, Laura J. Janke, Kristine C. Olson, Wencke Walter, Constance Baer, Torsten Haferlach, Elisabeth Paietta, Charles G. Mullighan, M. Madan Babu, Shunsuke Kimura, Wolfgang Kern, Chunxu Qu
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 21:S320-S321
Context: Chronic lymphoproliferative disorder of natural killer cells (CLPD-NK) is a subset of large granular lymphocyte (LGL) leukemia included as a provisional entity in the 2016 WHO classification of lymphoid neoplasms, which is characterized by c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8045f270f4b49aa384d54ba339e1e995
https://doi.org/10.1016/s2152-2650(21)01754-7
https://doi.org/10.1016/s2152-2650(21)01754-7
Autor:
Shunsuke Kimura, Constance Baer, Mitra S Rana, Andrew Kleist, David J. Feith, Wencke Walter, Manja Meggendorfer, Thomas L. Olson, HeeJin Cheon, Kristine C. Olson, Aakrosh Ratan, Martha-Lena Mueller, James M. Foran, Laura Janke, Chunxu Qu, Ravi Kalathur, Claudia Haferlach, Wolfgang Kern, Elisabeth Paietta, M. Madan Babu, Thomas P. Loughran, Ilaria Iacobucci, Torsten Haferlach, Charles G Mullighan
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 21:S222
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4527fd89595928647b8dc78b79f7189c
https://doi.org/10.1016/s2152-2650(21)01397-5
https://doi.org/10.1016/s2152-2650(21)01397-5
Autor:
Rui J Sousa, Anna Bianchi-Smiraglia, Dominic J. Smiraglia, Mitra S. Rana, Brittany C. Lipchick, Sudha Moparthy, Edward Hurley, Hayley C. Affronti, Leslie M. Paul, Archis Bagati, Eugene S. Kandel, C E Foley, Kalyana Moparthy, Maria Laura Feltri, Mikhail A. Nikiforov, Emily E. Fink, Andrei V. Bakin
Publikováno v:
Nature methods
GTP is a major regulator of multiple cellular processes, but tools for quantitative evaluation of GTP levels in live cells have not been available. We report the development and characterization of genetically encoded GTP sensors, which we constructe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2533ca794c3ef9331c94721a9e1a567d
https://doi.org/10.1038/nmeth.4404
https://doi.org/10.1038/nmeth.4404
Autor:
Thomas L. Olson, Ilaria Iacobucci, Constance Baer, Torsten Haferlach, Mitra S Rana, Ravi C. Kalathur, Wolfgang Kern, Shunsuke Kimura, Thomas P. Loughran, Aakrosh Ratan, Manja Meggendorfer, Martha-Lena Müller, Claudia Haferlach, David J. Feith, Charles G. Mullighan, Wencke Walter, Chunxu Qu
Publikováno v:
Blood. 136:19-19
Background: The pathogenesis of chronic lymphoproliferative disorder of NK-cells (CLPD-NK) is poorly understood. Mutations in the JAK/STAT pathway (especially STAT3) are found in 30% of patients, but the genetic or exogenous drivers responsible for o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bd451d9e6f0e664b5fd1898be8da628
https://doi.org/10.1182/blood-2020-140695
https://doi.org/10.1182/blood-2020-140695
Publikováno v:
Biochemistry
An essential prerequisite for in vitro biochemical or structural studies is a construct that is amenable to high level expression and purification and is biochemically "well-behaved". In the field of membrane protein research, the use of green fluore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6828611b1e5f7dbba28cf2f1fc60f21c
https://pubmed.ncbi.nlm.nih.gov/30481009
https://pubmed.ncbi.nlm.nih.gov/30481009
Wnt proteins regulate a large number of processes, including cellular growth, differentiation, and tissue homeostasis, through the highly conserved Wnt signaling pathway in metazoans. Porcupine (PORCN) is an endoplasmic reticulum (ER)-resident integr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0dd5aa6cf8a5f62b4d0ac1405e9d21c
https://europepmc.org/articles/PMC6322882/
https://europepmc.org/articles/PMC6322882/
