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Metronomic Administration of Topotecan Alone and in Combination with Docetaxel Inhibits Epithelial-mesenchymal Transition in Aggressive Variant Prostate Cancers.

Autor: Mitra Ghosh T; Department of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, Alabama.; Division of Urology, Department of Surgery, Mass General Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts., Mazumder S; Department of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, Alabama.; Center for Pharmacogenomics and Single-Cell Omics (AUPharmGx), Harrison College of Pharmacy, Auburn University, Auburn, Alabama., Davis J; Department of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, Alabama., Yadav J; Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, Alabama., Akinpelu A; Department of Chemical Engineering, Samuel Ginn College of Engineering, Auburn University, Auburn, Alabama., Alnaim A; Department of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, Alabama., Kumar H; Department of Biology and Canter for Cancer Research, Tuskegee University, Tuskegee, Alabama., Waliagha R; Department of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, Alabama., Church Bird AE; Flow Cytometry and High-Speed Cell Sorting Laboratory, Auburn University, Auburn, Alabama., Rais-Bahrami S; UAB O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, Alabama.; Department of Urology, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, Alabama.; Department of Radiology, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, Alabama.; Department of Pathology, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, Alabama., Bird RC; Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, Alabama., Mistriotis P; Department of Chemical Engineering, Samuel Ginn College of Engineering, Auburn University, Auburn, Alabama., Mishra A; Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, Alabama., Yates CC; Department of Biology and Canter for Cancer Research, Tuskegee University, Tuskegee, Alabama.; UAB O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, Alabama.; Department of Pathology, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, Alabama.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.; Department of Urology, Johns Hopkins University School of Medicine, Baltimore, Maryland., Mitra AK; Department of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, Alabama.; Center for Pharmacogenomics and Single-Cell Omics (AUPharmGx), Harrison College of Pharmacy, Auburn University, Auburn, Alabama.; UAB O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, Alabama., Arnold RD; Department of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University, Auburn, Alabama.; Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, Alabama.; UAB O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, Alabama.

Publikováno v: Cancer research communications [Cancer Res Commun] 2023 Jul 19; Vol. 3 (7), pp. 1286-1311. Date of Electronic Publication: 2023 Jul 19 (Print Publication: 2023).