Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Mitotic spindle assembly checkpoint"'
Autor:
Bradley J. Kemp, Anil N. Kurup, Sean P. Cleary, Danielle E. Jondal, Julie K. Heimbach, Mark Jacobson, Garima Suman, Jun Yin, Tyler Zemla, James C. Andrews, Lewis R. Roberts, Brian T. Welch, Anurima Patra, Scott M. Thompson, Eric C. Ehman, Sudhakar K. Venkatesh, Amit Mahipal, Mark J. Truty, Zongming E. Chen, Geoffrey B. Johnson, Chen Wang, Rory L. Smoot, Chad J. Fleming, Kymberly D. Watt, Michael Torbenson, Nguyen H Tran, David A. Woodrum, Zachary C. Fogarty, Ajit H. Goenka
Publikováno v:
Hepatology Communications. 6:1172-1185
Prostate-specific membrane antigen (PSMA) is a validated target for molecular diagnostics and targeted radionuclide therapy. Our purpose was to evaluate PSMA expression in hepatocellular carcinoma (HCC), cholangiocarcinoma (CCA), and hepatic adenoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b86abdde4452c96ed1bffa6f9ff8c4c
https://doi.org/10.1002/hep4.1861
https://doi.org/10.1002/hep4.1861
Autor:
E.A. Abdalla, Christine F. Baes, Joaquim Casellas, Flavio S Schenkel, Angela Cánovas, Samir Id-Lahoucine, Benjamin J. Wood
Publikováno v:
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Abdalla, E. A.; Id-Lahoucine, S.; Cánovas, A.; Casellas, J.; Schenkel, F. S.; Wood, B. J.; Baes, C. F. (2020). Discovering lethal alleles across the turkey genome using a transmission ratio distortion approach. Animal genetics, 51(6), pp. 876-889. Wiley 10.1111/age.13003
Animal Genetics
Universitat Autònoma de Barcelona
Abdalla, E. A.; Id-Lahoucine, S.; Cánovas, A.; Casellas, J.; Schenkel, F. S.; Wood, B. J.; Baes, C. F. (2020). Discovering lethal alleles across the turkey genome using a transmission ratio distortion approach. Animal genetics, 51(6), pp. 876-889. Wiley 10.1111/age.13003
Animal Genetics
Summary Deviation from Mendelian inheritance expectations (transmission ratio distortion, TRD) has been observed in several species, including the mouse and humans. In this study, TRD was characterized in the turkey genome using both allelic (specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82bb32249dfaa5fdf4c885155111578
https://doi.org/10.1111/age.13003
https://doi.org/10.1111/age.13003
Publikováno v:
Annual Review of Cancer Biology. 4:257-278
The mitotic spindle assembly checkpoint (SAC) is an intricate cell signaling system that ensures the high fidelity and timely segregation of chromosomes during cell division. Mistakes in this process can lead to the loss, gain, or rearrangement of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30b1406e1378715cfa2fb8102e4d8122
https://doi.org/10.1146/annurev-cancerbio-030419-033541
https://doi.org/10.1146/annurev-cancerbio-030419-033541
Bioinformatics study on genes related to a high-risk postoperative recurrence of lung adenocarcinoma
Publikováno v:
Science progress. 104(3)
In this study, we aimed to screen out genes associated with a high risk of postoperative recurrence of lung adenocarcinoma and investigate the possible mechanisms of the involvement of these genes in the recurrence of lung adenocarcinoma. We identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3adb8203e3f1bbe73dd97d72e09f2a01
https://pubmed.ncbi.nlm.nih.gov/34304612
https://pubmed.ncbi.nlm.nih.gov/34304612
Autor:
Robert P. St.Onge, Joe Horecka, Ulrich Schlecht, Ronald W. Davis, Ana Aparicio, Colin J. B. Harvey, Kristen Kolberg, Maureen E. Hillenmeyer, Jian Li
Publikováno v:
Journal of Biological Chemistry. 294:1257-1266
Multidrug resistance is highly conserved in mammalian, fungal, and bacterial cells, is characterized by resistance to several unrelated xenobiotics, and poses significant challenges to managing infections and many cancers. Eukaryotes use a highly con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae29039d5807bc5633f9a6fc4c8a62d6
https://doi.org/10.1074/jbc.ra118.003904
https://doi.org/10.1074/jbc.ra118.003904
Autor:
Florian Koban, Michael Freissmuth
Monoamine transporters retrieve serotonin (SERT), dopamine (DAT) and norepinephrine (NET) from the synaptic cleft. Surface levels of transporters are also regulated by internalization. Clathrin-mediated endocytosis of cargo proteins requires adaptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79c3dc7afc10750dc67b758972689038
https://doi.org/10.1101/2021.06.09.447721
https://doi.org/10.1101/2021.06.09.447721
Autor:
David Cantú de León, Cristian Arriaga-Canon, Clementina Castro-Hernández, Salim Abraham Barquet-Muñoz, Antonio Bandala-Jacques, Diddier G Prada-Ortega, Luis A. Herrera, José Díaz-Chávez, Irwin A. Hernández-Cruz
Publikováno v:
Revista de investigaci�n Cl�nica. 72
Background Ovarian cancer is the most lethal gynecologic cancer. Although most patients respond adequately to the first-line therapy, up to 85% experience a recurrence of disease, which carries a poor prognosis. Mitotic arrest deficiency 1 is a prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd8fdf1dc30017b698138f43ca5972b3
https://doi.org/10.24875/ric.19003280
https://doi.org/10.24875/ric.19003280
Publikováno v:
American journal of physiology. Renal physiology. 319(4)
Mitotic spindle assembly checkpoint protein 2 (MAD2B), a well-known anaphase-promoting complex/cyclosome (APC/C) inhibitor and a small subunit of DNA polymerase-ζ, is critical for mitotic control and DNA repair. Previously, we detected a strong incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8921f8772785f63dab8a406a1b0ebcbf
https://pubmed.ncbi.nlm.nih.gov/32830536
https://pubmed.ncbi.nlm.nih.gov/32830536
Publikováno v:
J Biol Chem
BuGZ is a kinetochore component that binds to and stabilizes Bub3, a key player in mitotic spindle assembly checkpoint signaling. Bub3 is required for kinetochore recruitment of Bub1 and BubR1, two proteins that have essential and distinct roles in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c432bf7f4b8b0366f3b6581de247a51c
https://europepmc.org/articles/PMC7586226/
https://europepmc.org/articles/PMC7586226/
Publikováno v:
Bioorg Med Chem Lett
Our sphingosine kinase inhibitor (SKI) optimization studies originated with the optimization of the SKI-I chemotype by replacement of the substituted benzyl rings with substituted phenyl rings giving rise to the discovery of SKI-178. We have recently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02140231b50e170bc4e0fb4437c85ac9
https://europepmc.org/articles/PMC7541634/
https://europepmc.org/articles/PMC7541634/