Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Mitogen-Activated Protein Kinase Kinase Inhibitor"'
Autor:
Chihiro Murata, Yusuke Murakami, Takuma Fukui, Sakurako Shimokawa, Koh-Hei Sonoda, Kimihiko Fujisawa
Publikováno v:
Case Reports in Ophthalmology, Vol 13, Iss 2, Pp 542-549 (2022)
The aim of this paper was to report the cases of 3 consecutive patients with mitogen-activated protein kinase kinase inhibitor (MEKi)-associated retinopathy with characteristic multiple serous retinal detachments (SRDs). A functional analysis of the
Externí odkaz:
https://doaj.org/article/c18da8d9af9a42a7859cf58d240c0f23
Autor:
Mie Mochizuki, Satoshi Fukushima, Ayato Hayashi, Takashi Inozume, Hiroshi Koga, Zentaro Yamagata, Makoto Wada, Taku Fujimura, Jun Asai, Hiroshi Igaki, Hiroshi Yokomichi, Yasuhiro Nakamura, Kenjiro Namikawa
Publikováno v:
JMA Journal
Akademický článek
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Autor:
Alan P. Brown
Publikováno v:
Biomarkers in Drug Discovery and Development
Autor:
Haixia Cao, Changwen Jing, Jifeng Feng, Huizi Li, Jianzhong Wu, Siwen Liu, Zhuo Wang, Rong Ma, Yuanyuan Du
Publikováno v:
Molecular Medicine Reports
Mitogen‑activated protein kinase kinase (MEK) small molecule inhibitors have been investigated in preclinical or clinical trials for the treatment of cancer. In the present study the genetic test results of 120 patients with colorectal cancer (CRC)
MEK inhibition prevents TGF-β1-induced myofibroblast transdifferentiation in human tenon fibroblasts
Publikováno v:
Molecular Medicine Reports
Subconjunctival fibrosis represents the primary cause of postoperative failure of trabeculectomy, and at present there is a lack of effective intervention strategies. The present study aimed to investigate the effect of the mitogen‑activated protei
Publikováno v:
Journal of the American Academy of Dermatology. 82:998-1000
Akademický článek
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Autor:
Kunitoshi Konda, Noritoshi Kawate, Nobutada Sakagami, Shinji Hashimura, Hiromichi Tamada, Toshio Inaba
Publikováno v:
The Journal of Veterinary Medical Science
This study investigated whether treatment with the mitogen-activated protein kinase kinase inhibitor U0126 during in vitro maturation (IVM), which has previously been reported to improve oocyte developmental competence, is practical for use in calf p
Autor:
Martine J. Jager, Elon H.C. van Dijk, Gregorius P M Luyten, Camiel J. F. Boon, Johannes R. Vingerling, Wim H. J. Kruit
Publikováno v:
Acta ophthalmologica, 96(7), 712-718. Copenhagen Scriptor
Acta Ophthalmologica, 96(7), 712-718
Acta Ophthalmologica, 96(7), 712-718. Wiley-Blackwell Publishing Ltd
Acta Ophthalmologica, 96(7), 712-718
Acta Ophthalmologica, 96(7), 712-718. Wiley-Blackwell Publishing Ltd
Purpose To analyse ophthalmological adverse events associated with mitogen-activated protein kinase kinase (MEK) inhibition with pimasertib treatment for metastatic cutaneous melanoma (CM). Methods In this prospective observational, cohort-based, cro