Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Mitogen-Activated Protein Kinase 3/metabolism"'
Publikováno v:
Science signaling, vol. 10, no. 463, pp. 463
Wakefulness is accompanied by experience-dependent synaptic plasticity and an increase in activity-regulated gene transcription. Wake-induced genes are certainly markers of neuronal activity and may also directly regulate the duration of and need for
Publikováno v:
Medical Hypotheses. 78:183-190
Psoriasis is a genetically determined, almost worldwide-distributed inflammatory skin disease with overall higher prevalence among people of northern European ancestry. Since enhanced innate immunity is an important feature of the pathophysiology of
Autor:
Dylan Burger, Rhian M. Touyz, Augusto C. Montezano, Mahmoud Almasri, Mark T. Quinn, Hiba Yusuf, Gang He, David Lambeth, Ying He, Glaucia E. Callera, Karl-Heinz Krause, Andreia Z. Chignalia, Tamara M. Paravicini
Publikováno v:
Circulation Research, Vol. 106, No 8 (2010) pp. 1363-1373
Circulation research
Circulation research
Rationale : Although Nox5 (Nox2 homolog) has been identified in the vasculature, its regulation and functional significance remain unclear. Objectives : We sought to test whether vasoactive agents regulate Nox5 through Ca 2+ /calmodulin-dependent pro
Autor:
Philippe I. H. Bastiaens, Ekaterini Panopoulou, Theodore Fotsis, Sofia Bellou, Eleni Bagli, Mark A. Hink, Carol Murphy
Publikováno v:
American Journal of Physiology. Cell Physiology, 297(6), C1477-C1489. American Physiological Society
Vascular endothelial growth factor (VEGF) is a key angiogenic factor that regulates proliferation and migration of endothelial cells via phosphorylation of extracellular signal-regulated kinase-1/2 (ERK1/2) and p38, respectively. Here, we demonstrate
Autor:
François Mach, Maria Bertolotto, Franco Dallegri, Luciano Ottonello, Fabienne Burger, Fabrizio Montecucco, Giordano Bianchi, Ana Da Costa, Sabine Steffens
Publikováno v:
Cellular Signalling, Vol. 20, No 3 (2008) pp. 557-68
Strong evidence suggests that neutrophils may play an active role in acute and chronic inflammatory disorders, such as rheumatoid arthritis and atherosclerosis. Given the role of pro-inflammatory cytokine TNF-alpha in these inflammatory processes, we
Autor:
Xiaojie Li, Zhen Sun, Baohua Liu, Zhuojing Luo, Long Wang, Li Chen, Liu Yang, Weiguang Lu, Qiang Jie, Jian Liu, Qiang Huang, Bo Gao, Yaqian Hu
Publikováno v:
Scientific Reports
Gao, B, Huang, Q, Jie, Q, Lu, W G, Wang, L, Li, X J, Sun, Z, Hu, Y Q, Chen, L, Liu, B H, Liu, J, Yang, L & Luo, Z J 2015, ' GPR120 : A bi-potential mediator to modulate the osteogenic and adipogenic differentiation of BMMSCs ', Scientific Reports, vol. 5, 14080 . https://doi.org/10.1038/srep14080
Gao, B, Huang, Q, Jie, Q, Lu, W G, Wang, L, Li, X J, Sun, Z, Hu, Y Q, Chen, L, Liu, B H, Liu, J, Yang, L & Luo, Z J 2015, ' GPR120 : A bi-potential mediator to modulate the osteogenic and adipogenic differentiation of BMMSCs ', Scientific Reports, vol. 5, 14080 . https://doi.org/10.1038/srep14080
Free fatty acids display diverse effects as signalling molecules through GPCRs in addition to their involvement in cellular metabolism. GPR120, a G protein-coupled receptor for long-chain unsaturated fatty acids, has been reported to mediate adipogen
Autor:
Kazutoshi Mawatari, Masahiko Hoshijima, Yoshihiro Fukumoto, Koutatsu Shimozono, Shoichiro Nohara, Takanobu Nagata, Hiroki Aoki, Yusuke Sugi, Tomoko Minami, Tsutomu Imaizumi, Sachiko Kyogoku, Toyoharu Oba, Hideo Yasukawa, Sylvain Pradervand, Jinya Takahashi
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127942 (2015)
PLoS One, vol. 10, no. 5, pp. e0127942
PLoS ONE
PLoS One, vol. 10, no. 5, pp. e0127942
PLoS ONE
Myocardial ischemia reperfusion injury (IRI) adversely affects cardiac performance and the prognosis of patients with acute myocardial infarction. Although myocardial signal transducer and activator of transcription (STAT) 3 is potently cardioprotect
Autor:
Robert A. Hipskind, Manuel S. Rodriguez, Guillaume Bossis, Rosa Farràs, Elisabetta Andermarcher, Stefan Müller, Marc Piechaczyk, Isabelle Jariel-Encontre, Darja Schmidt, Cécile E. Malnou
Publikováno v:
Molecular and Cellular Biology
Molecular and Cellular Biology, American Society for Microbiology, 2005, 25 (16), pp.6964--79. ⟨10.1128/MCB.25.16.6964-6979.2005⟩
Molecular and Cellular Biology, American Society for Microbiology, 2005, 25 (16), pp.6964--79. ⟨10.1128/MCB.25.16.6964-6979.2005⟩
The inducible transcriptional complex AP-1, composed of c-Fos and c-Jun proteins, is crucial for cell adaptation to many environmental changes. While its mechanisms of activation have been extensively studied, how its activity is restrained is poorly
Autor:
René Lerch, Mohamed Asrih, Corinne Pellieux, Irène Papageorgiou, Christophe Albert Montessuit
Publikováno v:
American Journal of Physiology. Endocrinology and Metabolism, Vol. 301, No 5 (2011) pp. E836-43
American journal of physiology. Endocrinology and metabolism
American journal of physiology. Endocrinology and metabolism
We previously demonstrated that microtubule disruption impairs stimulation of glucose uptake in cardiomyocytes and that 9-cis retinoic acid (9cRA) treatment preserved both microtubule integrity and stimulated glucose transport. Herein we investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f4ffcc3443c0d1cdb59659732d946b
https://archive-ouverte.unige.ch/unige:88465
https://archive-ouverte.unige.ch/unige:88465
Autor:
Elizabeth A. Jares-Erijman, Olaf Jahn, Doerte Hesse, Uwe Plessmann, Reiner Hitt, Henning Urlaub, Soledad Galli, Juan José Poderoso, Thomas M. Jovin, Lennart Opitz
Publikováno v:
PLoS ONE
PLoS ONE 2009;4(10)
Biblioteca Digital (UBA-FCEN)
Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
instacron:UBA-FCEN
PLoS One
PLoS ONE, Vol 4, Iss 10, p e7541 (2009)
PLoS ONE 2009;4(10)
Biblioteca Digital (UBA-FCEN)
Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
instacron:UBA-FCEN
PLoS One
PLoS ONE, Vol 4, Iss 10, p e7541 (2009)
Extracellular signal-regulated protein kinase 1 and 2 (ERK1/2) are members of the MAPK family and participate in the transduction of stimuli in cellular responses. Their long-term actions are accomplished by promoting the expression of specific genes