Výsledky vyhledávání - "Mitochondrial translational termination"

The impact of maternal age on gene expression during the GV to MII transition in euploid human oocytes

Autor: K Pantos, Emmanouel Kanavakis, Helen M. Picton, John Huntriss, David Iles, Agni Pantou, T Vaxevanoglou, Panagiotis Ntostis, Georgia Kokkali

Publikováno v: Human Reproduction (Oxford, England)

STUDY QUESTION Are there age-related differences in gene expression during the germinal vesicle (GV) to metaphase II (MII) stage transition in euploid human oocytes? SUMMARY ANSWER A decrease in mitochondrial-related transcripts from GV to MII oocyte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff75649b8bac8a4ed8d240d09a57c0e
https://doi.org/10.1093/humrep/deab226

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Increased Paternal Age at Conception Is Associated with Transcriptomic Changes Involved in Mitochondrial Function in Elderly Individuals

Autor: Juulia Jylhävä, Antti Hervonen, Mikko Hurme, Saara Marttila, Laura Kananen, Tapio Nevalainen, Marja Jylhä

Publikováno v: PLoS ONE
PLoS ONE, Vol 11, Iss 11, p e0167028 (2016)

The increased paternal age at conception (PAC) has been associated with autism spectrum disorder (ASD), schizophrenia and other neurodevelopmental disorders, thus raising questions that imply, potential health concerns in the offspring. As opposed to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05375bb905bf9a6ab77d8d177526f1d9
https://doi.org/10.1371/journal.pone.0167028

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Single-Point Mutations in Domain-Ii of the Yeast Mitochondrial Release Factor Mrf-1 Affect Ribosome Binding

Autor: Herman J. Pel, Martijn Rep, Hendrikus Jan Dubbink, Leslie A. Grivell

Publikováno v: Nucleic Acids Research, 21(23), 5308-5315. Oxford University Press

We have recently described two yeast strains that are mutated in the MRF1 gene encoding the mitochondrial release factor mRF-1. Both mutants provoke gene-specific defects in mitochondrial translational termination. In the present study we report the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c197b260658c1eecaed21dfe23280b
https://dare.uva.nl/personal/pure/en/publications/singlepoint-mutations-in-domainii-of-the-yeast-mitochondrial-release-factor-mrf1-affect-ribosome-binding(b9deed8a-422a-47ee-827d-0c53b5e53703).html

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