Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Mitochondrial inner membrane fusion"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences
Cardiolipin is a tetra-acylated di-phosphatidylglycerol lipid enriched in the matrix-facing (inner) leaflet of the mitochondrial inner membrane. Cardiolipin plays an important role in regulating mitochondria function and dynamics. Yet, the mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48494d1ddc2300c2fbaee97194db9510
https://doi.org/10.3389/fmolb.2021.769135
https://doi.org/10.3389/fmolb.2021.769135
Autor:
Marcel V. Alavi
Publikováno v:
Biochim Biophys Acta Mol Cell Res
The neuropathological hallmarks of Alzheimer's Disease are plaques and neurofibrillary tangles. Yet, Alzheimer's is a complex disease with many contributing factors, such as energy-metabolic changes, which have been documented in autopsy brains from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eacfd2da57e3aeb5c32d0f8f54e87aca
https://europepmc.org/articles/PMC8525314/
https://europepmc.org/articles/PMC8525314/
Autor:
Hee Cheol Cho, Natasha Fernandez, Jin mo Gu, Elizabeth H. Kim, D. Brian Foster, Sandra I. Grijalva
Publikováno v:
Experimental & Molecular Medicine
Experimental and Molecular Medicine, Vol 51, Iss 9, Pp 1-12 (2019)
Experimental and Molecular Medicine, Vol 51, Iss 9, Pp 1-12 (2019)
Cardiac pacemaker cells of the sinoatrial node initiate each and every heartbeat. Compared with our understanding of the constituents of their electrical excitation, little is known about the metabolic underpinnings that drive the automaticity of pac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c3f40bd06b9a94f01c4ae6363298857
https://doi.org/10.1038/s12276-019-0303-6
https://doi.org/10.1038/s12276-019-0303-6
Publikováno v:
Nucleic acids research
Ataxia with oculomotor apraxia type 1 (AOA1) is an early onset progressive spinocerebellar ataxia caused by mutation in aprataxin (APTX). APTX removes 5′-AMP groups from DNA, a product of abortive ligation during DNA repair and replication. APTX de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f49379fb1e6075d4fbca3b2385a42eb
https://doi.org/10.1093/nar/gkz083
https://doi.org/10.1093/nar/gkz083
Optimal mitochondrial function determined by mitochondrial dynamics, morphology and activity is coupled to stem cell differentiation and organism development. However, the mechanisms of interaction of signaling pathways with mitochondrial morphology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134df8f86186a24fbaa091a3580ef69e
https://doi.org/10.1101/2021.01.08.425832
https://doi.org/10.1101/2021.01.08.425832
Autor:
Danyang Zhang, Xiaoyun Pang, Yan Zhang, Tongxin Niu, Fei Sun, Chunmei Zhu, Yujia Zhai, Wenbo Chen, Jun Ma
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Mammalian mitochondrial inner membrane fusion is mediated by optic atrophy 1 (OPA1). Under physiological conditions, OPA1 undergoes proteolytic processing to form a membrane-anchored long isoform (L-OPA1) and a soluble short isoform (S-OPA1). A combi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11ff911228bf920abf334c1a52399cfe
https://doi.org/10.7554/elife.50294
https://doi.org/10.7554/elife.50294
Autor:
Tadato Ban, Naotada Ishihara
Publikováno v:
Methods in Molecular Biology ISBN: 9781071606759
Mitochondria are highly dynamic organelles, which move and fuse to regulate their shape, size, and fundamental function. The dynamin-related GTPases play a critical role in mitochondrial membrane fusion. In vitro reconstitution of membrane fusion usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::364d75f740938c3112752939ad60e2f0
https://doi.org/10.1007/978-1-0716-0676-6_9
https://doi.org/10.1007/978-1-0716-0676-6_9
Publikováno v:
Journal of Biological Chemistry. 292:7115-7130
The protein optic atrophy 1 (OPA1) is a dynamin-related protein associated with the inner mitochondrial membrane and functions in mitochondrial inner membrane fusion and cristae maintenance. Inner membrane-anchored long OPA1 (L-OPA1) undergoes proteo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af6e44dca2f6e56d22a3a4690585e223
https://doi.org/10.1074/jbc.m116.762567
https://doi.org/10.1074/jbc.m116.762567
Mammalian mitochondrial inner membrane fusion is mediated by OPA1(optic atrophy 1). Under physiological condition, OPA1 undergoes proteolytic processing to form a membrane-anchored long isoform (L-OPA1) and a soluble short isoform (S-OPA1). A combina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90116a3935c2d580a119f0a0fc1c41f
Publikováno v:
Biochimica et biophysica acta. Bioenergetics. 1859(9)
Mitochondria are highly dynamic organelles that undergo frequent fusion and fission. The large GTPase optic atrophy 1 (OPA1) is identified as a core component of inner membrane (IM) fusion. OPA1 exists as the membrane-anchored L-OPA1 and the proteoly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a2e71d9fda8b45a8ccfa8bb26e2f121
https://pubmed.ncbi.nlm.nih.gov/29852142
https://pubmed.ncbi.nlm.nih.gov/29852142