Zobrazeno 1 - 10
of 353
pro vyhledávání: '"Mitochondrial impairment"'
Autor:
Eva Žerovnik
Publikováno v:
Exploration of Neuroscience, Vol 3, Iss 4, Pp 295-308 (2024)
A short overview of the main features of progressive myoclonus epilepsies (PMEs), such as Lafora disease (LD), neuronal ceroid lipofuscinoses (NCLs), and myoclonus epilepsy with ragged-red fibers (MERRF) is given. The stress of this review paper is p
Externí odkaz:
https://doaj.org/article/52cef95ae4d64d248c63a622a864e528
Autor:
Guifeng Su, Qianqing Yang, Heyang Zhou, Ying Huang, Shiyun Nie, Dan Wang, Guangchao Ma, Shaohua Zhang, Lingmei Kong, Chenggang Zou, Yan Li
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9717 (2024)
Due to limited drug efficacy and drug resistance, it is urgent to explore effective anti-liver cancer drugs. Repurposing drugs is an efficient strategy, with advantages including reduced costs, shortened development cycles, and assured safety. In thi
Externí odkaz:
https://doaj.org/article/9c9c49554d444d3aadaefa48cd1d6a7f
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Cisplatin is a widely used and effective chemotherapeutic agent against cancer. However, nephrotoxicity is one of the most common side effects of cisplatin, and it can proceed to acute kidney injury (AKI). Studies have reported th
Externí odkaz:
https://doaj.org/article/341cdbdd84ab406eb20ca097635732dd
Autor:
Andrea Antonosante, Vanessa Castelli, Martina Sette, Margherita Alfonsetti, Mariano Catanesi, Elisabetta Benedetti, Matteo Ardini, Annamaria Cimini, Michele d’Angelo
Publikováno v:
Biological Research, Vol 56, Iss 1, Pp 1-22 (2023)
Abstract Background The underlying mechanism of Parkinson’s disease are still unidentified, but excitotoxicity, oxidative stress, and neuroinflammation are considered key actors. Proliferator activated receptors (PPARs) are transcription factors in
Externí odkaz:
https://doaj.org/article/178c395877d247fa99a564896b677857
Autor:
Yafei Zhang, Bingqian Yang, Chengwei Tu, Yifan Ping, Shuhong Chen, Tong Wu, Zheyu Zhao, Yixin Mao, Zhan Yang, Zelin Cao, Jianmin Li, Kate Huang, Xi Ding, Gang Wu, Peng Zou, Zhennan Deng, Xiaoyu Sun
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Oral squamous cell carcinoma (OSCC) is one of the most prevalent and fatal oral cancers. Mitochondria-targeting therapies represent promising strategies against various cancers, but their applications in treating OSCC are limited.
Externí odkaz:
https://doaj.org/article/93397a6b0bf942b6ac4c2b59107da2c4
Autor:
Yang Yang, Kai-Yuan Zhang, Xue-Zhu Chen, Chuan-Yan Yang, Ju Wang, Xue-Jiao Lei, Yu-Lian Quan, Wei-Xiang Chen, Heng-Li Zhao, Li-Kun Yang, Yu-Hai Wang, Yu-Jie Chen, Hua Feng
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 4, Pp 849-855 (2023)
The mitochondrial permeability transition pore is a nonspecific transmembrane channel. Inhibition of mitochondrial permeability transition pore opening has been shown to alleviate mitochondrial swelling, calcium overload, and axonal degeneration. Cyc
Externí odkaz:
https://doaj.org/article/0d2acab39f97429295ed704e4e067263
Publikováno v:
Neuropsychiatric Disease and Treatment, Vol Volume 18, Pp 2455-2466 (2022)
Aqian Hu,1,* Faping Li,2,* Lei Guo,1 Xiaoxi Zhao,1 Xiaojun Xiang1 1Department of Psychiatry and National Clinical Research Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, 410011, People’s Repu
Externí odkaz:
https://doaj.org/article/4094b130a16b42a4a98dc29038351197
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Autor:
Pouria Mobasher, Mohammad Mehdi Ommati, Asma Najibi, Amin Reza Akbarizadeh, Younes Ghasemi, Reza Heidari
Publikováno v:
Trends in Pharmaceutical Sciences, Vol 7, Iss 3, Pp 179-190 (2021)
Mitochondria are cellular power plants known as essential organelles for energy (ATP) metabolism. However, today it is evident that various vital compounds are partially or exclusively synthesized in mitochondria. Moreover, this organelle plays a piv
Externí odkaz:
https://doaj.org/article/51672dcfa7d64e1fba997c836d266112