Mitochondrial uncoupling proteins protect human airway epithelial ciliated cells from oxidative damage.

Autor: Jain A; Department of Internal Medicine, Pappajohn Biomedical Institute, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242.; Department of Molecular Physiology and Biophysics, Pappajohn Biomedical Institute, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242., Kim BR; Department of Internal Medicine, Pappajohn Biomedical Institute, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242.; HHMI, Department of Internal Medicine, University of Iowa, Iowa City, IA 52242., Yu W; Department of Internal Medicine, Pappajohn Biomedical Institute, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242.; HHMI, Department of Internal Medicine, University of Iowa, Iowa City, IA 52242., Moninger TO; Department of Internal Medicine, Pappajohn Biomedical Institute, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242., Karp PH; Department of Internal Medicine, Pappajohn Biomedical Institute, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242.; HHMI, Department of Internal Medicine, University of Iowa, Iowa City, IA 52242., Wagner BA; Free Radical and Radiation Biology Program, Department of Radiation Oncology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242., Welsh MJ; Department of Internal Medicine, Pappajohn Biomedical Institute, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242.; Department of Molecular Physiology and Biophysics, Pappajohn Biomedical Institute, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242.; HHMI, Department of Internal Medicine, University of Iowa, Iowa City, IA 52242.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Mar 05; Vol. 121 (10), pp. e2318771121. Date of Electronic Publication: 2024 Feb 28.

Mitochondrial uncoupling proteins regulate the metabolic function of human Sertoli cells.

Autor: Carrageta DF; Clinical and Experimental Endocrinology, UMIB - Unit for Multidisciplinary Research in Biomedicine, ICBAS - School of Medicine and Biomedical Sciences, University of Porto, Rua Jorge de Viterbo Ferreira 228, Porto, Portugal.; Laboratory for Integrative and Translational Research in Population Health (ITR), University of Porto, Rua das Taipas 136, Porto, Portugal., Freire-Brito L; Clinical and Experimental Endocrinology, UMIB - Unit for Multidisciplinary Research in Biomedicine, ICBAS - School of Medicine and Biomedical Sciences, University of Porto, Rua Jorge de Viterbo Ferreira 228, Porto, Portugal.; Laboratory for Integrative and Translational Research in Population Health (ITR), University of Porto, Rua das Taipas 136, Porto, Portugal., Guerra-Carvalho B; Clinical and Experimental Endocrinology, UMIB - Unit for Multidisciplinary Research in Biomedicine, ICBAS - School of Medicine and Biomedical Sciences, University of Porto, Rua Jorge de Viterbo Ferreira 228, Porto, Portugal.; Laboratory for Integrative and Translational Research in Population Health (ITR), University of Porto, Rua das Taipas 136, Porto, Portugal.; LAQV & REQUIMTE, Department of Chemistry, University of Aveiro, Aveiro, Portugal.; Department of Pathology, Faculty of Medicine, University of Porto, Alameda Prof. Hernâni Monteiro, Porto, Portugal., Bernardino RL; Clinical and Experimental Endocrinology, UMIB - Unit for Multidisciplinary Research in Biomedicine, ICBAS - School of Medicine and Biomedical Sciences, University of Porto, Rua Jorge de Viterbo Ferreira 228, Porto, Portugal.; Laboratory for Integrative and Translational Research in Population Health (ITR), University of Porto, Rua das Taipas 136, Porto, Portugal., Monteiro BS; Clinical and Experimental Endocrinology, UMIB - Unit for Multidisciplinary Research in Biomedicine, ICBAS - School of Medicine and Biomedical Sciences, University of Porto, Rua Jorge de Viterbo Ferreira 228, Porto, Portugal.; Laboratory for Integrative and Translational Research in Population Health (ITR), University of Porto, Rua das Taipas 136, Porto, Portugal., Barros A; Department of Pathology, Faculty of Medicine, University of Porto, Alameda Prof. Hernâni Monteiro, Porto, Portugal.; i3S - Instituto de Investigação e Inovação em Saúde, University of Porto, R. Alfredo Allen 208, Porto, Portugal.; Centre for Reproductive Genetics Prof. Alberto Barros, Av. do Bessa, Porto, Portugal., Oliveira PF; LAQV & REQUIMTE, Department of Chemistry, University of Aveiro, Aveiro, Portugal., Monteiro MP; Clinical and Experimental Endocrinology, UMIB - Unit for Multidisciplinary Research in Biomedicine, ICBAS - School of Medicine and Biomedical Sciences, University of Porto, Rua Jorge de Viterbo Ferreira 228, Porto, Portugal.; Laboratory for Integrative and Translational Research in Population Health (ITR), University of Porto, Rua das Taipas 136, Porto, Portugal., Alves MG; Department of Medical Sciences, Institute of Biomedicine (iBiMED), University of Aveiro, Aveiro, Portugal.

Publikováno v: Reproduction (Cambridge, England) [Reproduction] 2024 Jan 16; Vol. 167 (2). Date of Electronic Publication: 2024 Jan 16 (Print Publication: 2024).

Structural models of mitochondrial uncoupling proteins obtained in DPC micelles are not functionally relevant.

Autor: Piel MS; Laboratoire de Biologie Physico-Chimique des Protéines Membranaires, LBPC-PM, CNRS, UMR7099, Université de Paris, France.; Institut de Biologie Physico-Chimique, Fondation Edmond de Rothschild pour le Développement de la Recherche Scientifique, Paris, France., Masscheleyn S; Laboratoire de Biologie Physico-Chimique des Protéines Membranaires, LBPC-PM, CNRS, UMR7099, Université de Paris, France.; Institut de Biologie Physico-Chimique, Fondation Edmond de Rothschild pour le Développement de la Recherche Scientifique, Paris, France., Bouillaud F; Institut Cochin, INSERM, CNRS, Université de Paris, France., Moncoq K; Laboratoire de Biologie Physico-Chimique des Protéines Membranaires, LBPC-PM, CNRS, UMR7099, Université de Paris, France.; Institut de Biologie Physico-Chimique, Fondation Edmond de Rothschild pour le Développement de la Recherche Scientifique, Paris, France., Miroux B; Laboratoire de Biologie Physico-Chimique des Protéines Membranaires, LBPC-PM, CNRS, UMR7099, Université de Paris, France.; Institut de Biologie Physico-Chimique, Fondation Edmond de Rothschild pour le Développement de la Recherche Scientifique, Paris, France.

Publikováno v: The FEBS journal [FEBS J] 2021 May; Vol. 288 (9), pp. 3024-3033. Date of Electronic Publication: 2020 Dec 07.

UCP2, a Member of the Mitochondrial Uncoupling Proteins: An Overview from Physiological to Pathological Roles

Autor: Salvatore Nesci, Speranza Rubattu

Publikováno v: Biomedicines, Vol 12, Iss 6, p 1307 (2024)

UCP2 is an uncoupling protein homolog to UCP1. Unlike UCP1, which participates in non-shivering thermogenesis by uncoupling oxidative phosphorylation (OXPHOS), UCP2 does not perform a canonical H+ leak, consuming the protonmotive force (Δp) through

Externí odkaz: https://doaj.org/article/1b971183c9064b72b0fa4e35e4870175

Functional characterization of the mitochondrial uncoupling proteins from the white shrimp Litopenaeus vannamei

Autor: Mendez-Romero, Ofelia, Rodriguez-Armenta, Chrystian, Uribe-Carvajal, Salvador, Muhlia-Almazan, Adriana

Publikováno v: In BBA - Bioenergetics 1 August 2020 1861(8)