Zobrazeno 1 - 10
of 1 200
pro vyhledávání: '"Mitochondria-targeting"'
Publikováno v:
Smart Materials in Medicine, Vol 5, Iss 3, Pp 373-385 (2024)
Prodrug nanoparticles have been explored as an effective means for drug delivery because of controlled drug release in a stimulus-responsive manner. Organellar-targeted drug delivery could enhance the efficacy of cancer therapy. Herein, pH and light
Externí odkaz:
https://doaj.org/article/185cd2b49e5040128d4f75d061d0b4bd
Autor:
Xianghui Li, Haoran Wang, Zhiyan Li, Song Liu, Yuanyuan Chen, Zhuren Ruan, Zhijian Yao, Gao Wei, Cunwei Cao, Wenjun Zheng, Wenxian Guan
Publikováno v:
MedComm, Vol 5, Iss 11, Pp n/a-n/a (2024)
Abstract The precise and effective activation of the immune response is crucial in promising therapy curing cancer. Photoimmunotherapy (PIT) is an emerging strategy for precise regulation and highly spatiotemporal selectivity. However, this approach
Externí odkaz:
https://doaj.org/article/f72541df1e2246e39efa0bb73873cf5a
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 6463-6483 (2024)
Luxun Yang,1,* Haiying Ran,2,* Yaru Yin,1 Jing Liu,1 Binghui Lu,1 Xi Ran,3 Shenglin Luo,1 Weidong Wang,4 Zhangyou Yang,5 Rong Li1 1Institute of Combined Injury, National Key Laboratory of Trauma and Chemical Poisoning, Army Key Laboratory of
Externí odkaz:
https://doaj.org/article/5d7ebcf5a68e404782fdd875c32a4e24
Autor:
Anne P. M. Beerkens, Daan F. Boreel, James A. Nathan, Jiri Neuzil, Gang Cheng, Balaraman Kalyanaraman, Micael Hardy, Gosse J. Adema, Sandra Heskamp, Paul N. Span, Johan Bussink
Publikováno v:
Cancer & Metabolism, Vol 12, Iss 1, Pp 1-10 (2024)
Abstract Background Hypoxia is a common feature of many solid tumors and causes radiotherapy and immunotherapy resistance. Pharmacological inhibition of oxidative phosphorylation (OXPHOS) has emerged as a therapeutic strategy to reduce hypoxia. Howev
Externí odkaz:
https://doaj.org/article/6158a99077a34dd2a03b9ab6923fa43f
Publikováno v:
Carbohydrate Polymer Technologies and Applications, Vol 9, Iss , Pp 100634- (2025)
Background: Chitosan, an innately sourced polymer, is esteemed for its biological compatibility and breakdown. Its cationic properties enable good interaction with diverse biological molecules, particularly beneficial in drug-delivery systems. Its ca
Externí odkaz:
https://doaj.org/article/1509a050f8694c4b90a0e8c543a4aca2
Publikováno v:
Next Materials, Vol 5, Iss , Pp 100230- (2024)
Local hypoxia in tumors poses significant challenges to the effectiveness of oxygen-dependent photodynamic therapy (PDT). Herein, a versatile mitochondrial targeting and pH-responsive nanozyme platform (noted as Mito CPs-p) is developed for solving l
Externí odkaz:
https://doaj.org/article/3c54e9b6b2054c129355ef4c334b13e9
Publikováno v:
Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)
Abstract The combination of cuproptosis and immune checkpoint inhibition has shown promise in treating malignant tumors. However, it remains a challenge to deliver copper ions and immune checkpoint inhibitors efficiently and simultaneously to tumors.
Externí odkaz:
https://doaj.org/article/b40d3794215e4aa69eef987751b07cdb
Publikováno v:
Exploration, Vol 4, Iss 4, Pp n/a-n/a (2024)
Abstract For its vital role in maintaining cellular activity and survival, mitochondrion is highly involved in various diseases, and several strategies to target mitochondria have been developed for specific imaging and treatment. Among these approac
Externí odkaz:
https://doaj.org/article/ec4db3005f894e25a1407668146f929d
Autor:
Weiguo Song, Hekai Yang, Ying Wang, Shuzhen Chen, Wenda Zhong, Qian Wang, Wenshuo Ding, Guangzhao Xu, Chen Meng, Ying Liang, Zhe‐Sheng Chen, Shuhua Cao, Liuya Wei, Fahui Li
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract Multi‐drug resistance (MDR) is a major cause of cancer therapy failure. Photodynamic therapy (PDT) is a promising modality that can circumvent MDR and synergize with chemotherapies, based on the generation of reactive oxygen species (ROS)
Externí odkaz:
https://doaj.org/article/dfe4096d398d4ba78db0668db03a63d9