Zobrazeno 1 - 10
of 1 591
pro vyhledávání: '"Mitochondria-targeted"'
Autor:
Yong Zhou, Yang Jin, Tianyu Wu, Yinfeng Wang, Yuanhang Dong, Pei Chen, Changchang Hu, Ningping Pan, Chaoshuang Ye, Li Shen, Mengyan Lin, Tao Fang, Ruijin Wu
Publikováno v:
Journal of Advanced Research, Vol 65, Iss , Pp 211-226 (2024)
Background: The reportedly high mutation rate of mitochondrial DNA (mtDNA) may be attributed to the absence of histone protection and complete repair mechanisms. Mitochondrial heteroplasmy refers to the coexistence of wild-type and mutant mtDNA. Most
Externí odkaz:
https://doaj.org/article/0ba2eb553f1e4981aba3f06198dbe29f
SS-31 protects diabetic nephropathy progression: A systematic review of in vivo and in vitro studies
Autor:
Jonathan Christianto Sutadji, Dian Anggraini Permatasari Musalim, David Setyo Budi, Jennifer Susanto, Fanny Gunawan, Chaq El Chaq Zamzam Multazam, Citrawati Dyah Kencono Wungu
Publikováno v:
Journal of Pharmacy & Pharmacognosy Research, Vol 12, Iss 5, Pp 956-971 (2024)
Context: Diabetic nephropathy is the leading cause of end-stage renal disease and also death in the world. Administration of Szeto-Schiller-31 (SS-31) as a potential therapeutic candidate that can decrease the renal function damage progressivity in d
Externí odkaz:
https://doaj.org/article/aa1589c433214f1598dca3ff2ac93bca
Autor:
Minghui Chen, Hanbo Xu, Pengzhao Chang, Xueqi Li, Shuang Liu, Lingyue Xu, Kai Xu, Guohui Cheng
Publikováno v:
Materials Today Bio, Vol 29, Iss , Pp 101318- (2024)
Mitochondria-targeted photodynamic therapy (PDT) has emerged as one of the most promising antitumor therapies, as it significantly enhances the efficacy of photosensitizers. An efficient and biocompatible nanocarrier to deliver cationic photosensitiz
Externí odkaz:
https://doaj.org/article/150a3fa0109e42558f9d1defba9f8658
Publikováno v:
Bioactive Materials, Vol 36, Iss , Pp 490-507 (2024)
Immunogenic cell death (ICD) represents a modality of apoptosis distinguished by the emanation of an array of damage-related molecular signals. This mechanism introduces a novel concept in the field of contemporary tumor immunotherapy. The inception
Externí odkaz:
https://doaj.org/article/9bf7fa3a28964e54b14a96f247f5e83c
Autor:
Wen Xie, Sushruta Koppula, Mayur B. Kale, Lashin S. Ali, Nitu L. Wankhede, Mohit D. Umare, Aman B. Upaganlawar, Ahmed Abdeen, Elturabi E. Ebrahim, Mohamed El-Sherbiny, Tapan Behl, Bairong Shen, Rajeev K. Singla
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Epilepsy, a complex neurological condition marked by recurring seizures, is increasingly recognized for its intricate relationship with mitochondria, the cellular powerhouses responsible for energy production and calcium regulation. This review offer
Externí odkaz:
https://doaj.org/article/b0b6ae85816542318fba434cf71c925d
Autor:
Chen, Minghui a, c, 1, Xu, Hanbo a, d, 1, Chang, Pengzhao a, 1, Li, Xueqi a, c, Liu, Shuang b, Xu, Lingyue a, Xu, Kai a, c, ⁎⁎, Cheng, Guohui b, c, ⁎
Publikováno v:
In Materials Today Bio December 2024 29
Autor:
Aysegul Ekmekcioglu, Ozgul Gok, Devrim Oz-Arslan, Meryem Sedef Erdal, Yasemin Yagan Uzuner, Meltem Muftuoglu
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 950 (2024)
The special bilayer structure of mitochondrion is a promising therapeutic target in the diagnosis and treatment of diseases such as cancer and metabolic diseases. Nanocarriers such as liposomes modified with mitochondriotropic moieties can be develop
Externí odkaz:
https://doaj.org/article/ed14f27204044a4fa7213122d05d4bc7
Autor:
Zheng, Jianguo a, b, 1, Zhang, Aijing a, b, 1, Du, Qinglong a, b, Li, Chi c, Zhao, Zhongwei a, Li, Luchao a, Zhang, Zhao a, Qin, Xin a, Li, Yi d, ⁎, Wang, Kang-Nan c, ⁎, Yu, Nengwang a, ⁎
Publikováno v:
In Journal of Colloid And Interface Science April 2025 683 Part 1:420-431
Autor:
Fang, Bin a, b, 1, Bai, Hua a, 1, Zhang, Jiaxin a, Wang, Limin a, Li, PanPan a, Ge, Yihao d, Yang, Hui d, Wang, Hui c, Peng, Bo a, Hu, Wenbo a, Ma, Huili e, Chen, Xi d, ⁎⁎, Fu, Li b, ⁎⁎⁎, Li, Lin a, c, f, ⁎
Publikováno v:
In Biomaterials April 2025 315
Autor:
Konstantin G. Lyamzaev, He Huan, Alisa A. Panteleeva, Ruben A. Simonyan, Armine V. Avetisyan, Boris V. Chernyak
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 730 (2024)
Lipid peroxidation plays an important role in various pathologies and aging, at least partially mediated by ferroptosis. The role of mitochondrial lipid peroxidation during ferroptosis remains poorly understood. We show that supplementation of exogen
Externí odkaz:
https://doaj.org/article/ad32d22f44b64d288a76ed595cc66194