Zobrazeno 1 - 10
of 1 560
pro vyhledávání: '"Mitochondria targeted"'
SS-31 protects diabetic nephropathy progression: A systematic review of in vivo and in vitro studies
Autor:
Jonathan Christianto Sutadji, Dian Anggraini Permatasari Musalim, David Setyo Budi, Jennifer Susanto, Fanny Gunawan, Chaq El Chaq Zamzam Multazam, Citrawati Dyah Kencono Wungu
Publikováno v:
Journal of Pharmacy & Pharmacognosy Research, Vol 12, Iss 5, Pp 956-971 (2024)
Context: Diabetic nephropathy is the leading cause of end-stage renal disease and also death in the world. Administration of Szeto-Schiller-31 (SS-31) as a potential therapeutic candidate that can decrease the renal function damage progressivity in d
Externí odkaz:
https://doaj.org/article/aa1589c433214f1598dca3ff2ac93bca
Publikováno v:
Bioactive Materials, Vol 36, Iss , Pp 490-507 (2024)
Immunogenic cell death (ICD) represents a modality of apoptosis distinguished by the emanation of an array of damage-related molecular signals. This mechanism introduces a novel concept in the field of contemporary tumor immunotherapy. The inception
Externí odkaz:
https://doaj.org/article/9bf7fa3a28964e54b14a96f247f5e83c
Autor:
Wen Xie, Sushruta Koppula, Mayur B. Kale, Lashin S. Ali, Nitu L. Wankhede, Mohit D. Umare, Aman B. Upaganlawar, Ahmed Abdeen, Elturabi E. Ebrahim, Mohamed El-Sherbiny, Tapan Behl, Bairong Shen, Rajeev K. Singla
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Epilepsy, a complex neurological condition marked by recurring seizures, is increasingly recognized for its intricate relationship with mitochondria, the cellular powerhouses responsible for energy production and calcium regulation. This review offer
Externí odkaz:
https://doaj.org/article/b0b6ae85816542318fba434cf71c925d
Autor:
Aysegul Ekmekcioglu, Ozgul Gok, Devrim Oz-Arslan, Meryem Sedef Erdal, Yasemin Yagan Uzuner, Meltem Muftuoglu
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 950 (2024)
The special bilayer structure of mitochondrion is a promising therapeutic target in the diagnosis and treatment of diseases such as cancer and metabolic diseases. Nanocarriers such as liposomes modified with mitochondriotropic moieties can be develop
Externí odkaz:
https://doaj.org/article/ed14f27204044a4fa7213122d05d4bc7
Akademický článek
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Autor:
Konstantin G. Lyamzaev, He Huan, Alisa A. Panteleeva, Ruben A. Simonyan, Armine V. Avetisyan, Boris V. Chernyak
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 730 (2024)
Lipid peroxidation plays an important role in various pathologies and aging, at least partially mediated by ferroptosis. The role of mitochondrial lipid peroxidation during ferroptosis remains poorly understood. We show that supplementation of exogen
Externí odkaz:
https://doaj.org/article/ad32d22f44b64d288a76ed595cc66194
Autor:
Pavel A. Nazarov, Vladislav S. Maximov, Alexander M. Firsov, Marina V. Karakozova, Veronika Panfilova, Elena A. Kotova, Maxim V. Skulachev, Yuri N. Antonenko
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6137 (2024)
Mitochondria-targeted antioxidants (MTAs) have been studied quite intensively in recent years as potential therapeutic agents and vectors for the delivery of other active substances to mitochondria and bacteria. Their most studied representatives are
Externí odkaz:
https://doaj.org/article/60d327de2eb64c31baf99c99657766e1
Autor:
Teresa Cunha-Oliveira, Liliana Montezinho, Rui F. Simões, Marcelo Carvalho, Elisabete Ferreiro, Filomena S. G. Silva
Publikováno v:
Cells, Vol 13, Iss 3, p 248 (2024)
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by the progressive loss of motor neurons, for which current treatment options are limited. Recent studies have shed light on the role of mitochondria in ALS
Externí odkaz:
https://doaj.org/article/789c5fe7a8b043598f3fcf8777a6faee
Publikováno v:
Cancers, Vol 16, Iss 2, p 351 (2024)
Radiotherapy is a non-invasive method that is widely applied to treat and alleviate cancers. However, radiation-induced effects in the immune system are associated with several side effects via an increase in oxidative stress and the inflammatory res
Externí odkaz:
https://doaj.org/article/fb2fb44b0e67470681fd3d86fdefe0b8
Autor:
Laien Zhao, Longbing Ling, Jing Lu, Feng Jiang, Jianchao Sun, Zhen Zhang, Yanmei Huang, Xiaoqian Liu, Yanjuan Zhu, Xiaoxuan Fu, Shengjun Peng, Wenze Yuan, Ruikang Zhao, Zhuhong Zhang
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 3, Pp n/a-n/a (2023)
Abstract Retinal ischemia–reperfusion (RIR) injury is involved in the pathogenesis of various vision‐threatening diseases. The overproduction of reactive oxygen species (ROS) is thought to be the main cause of RIR injury. A variety of natural pro
Externí odkaz:
https://doaj.org/article/9683c1e1b1ce4cb8a81fa294d187a406