Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mitochondria in Health and Disease"'
Publikováno v:
The Journal of Physiology
Sarcomeric gene mutations are associated with the development of hypertrophic cardiomyopathy (HCM). Current drug therapeutics for HCM patients are effective in relieving symptoms, but do not prevent or reverse disease progression. Moreover, due to he
Publikováno v:
Biochemical Society Transactions
Influential research by Warburg and Cori in the 1920s ignited interest in how cancer cells' energy generation is different from that of normal cells. They observed high glucose consumption and large amounts of lactate excretion from cancer cells comp
Autor:
Carlo Viscomi
Publikováno v:
Biochemical Society Transactions
Mitochondrial disorders are a group of genetic diseases affecting the energy-converting process of oxidative phosphorylation. The extreme variability of symptoms, organ involvement, and clinical course represent a challenge to the development of effe
Publikováno v:
Biochemical Society Transactions
A sufficiently complex set of molecules, if subject to perturbation, will self-organize and show emergent behaviour. If such a system can take on information it will become subject to natural selection. This could explain how self-replicating molecul
Autor:
Tamara Sirey, Chris P. Ponting
Publikováno v:
Sirey, T & Ponting, C 2016, ' Insights into the post-transcriptional regulation of the mitochondrial electron transport chain ', Biochemical Society Transactions . https://doi.org/10.1042/BST20160100
Biochemical Society Transactions
Biochemical Society Transactions
The regulation of the mitochondrial electron transport chain is central to the control of cellular homeostasis. There are significant gaps in our understanding of how the expression of the mitochondrial and nuclear genome-encoded components of the el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19110258834713c17168ca6ee45f17c2
https://hdl.handle.net/20.500.11820/01726079-31cc-4e0c-bd3e-d69d1a5f3eb9
https://hdl.handle.net/20.500.11820/01726079-31cc-4e0c-bd3e-d69d1a5f3eb9
Autor:
Suzannah A. Williams, Janet Carver, Dagan Wells, Eszter Dombi, Joanna Poulton, Iain G. Johnston, C Liao, Tim Child, Alan Diot, Karl J. Morten, Tiffany A. Lodge
Publikováno v:
Biochemical Society Transactions
One in 400 people has a maternally inherited mutation in mtDNA potentially causing incurable disease. In so-called heteroplasmic disease, mutant and normal mtDNA co-exist in the cells of carrier women. Disease severity depends on the proportion of in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152d65dac418778b783a37d978009ffb
https://doi.org/10.1042/bst20160095
https://doi.org/10.1042/bst20160095