Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Mitochondria/genetics"'
Autor:
Kate N. O’Neill, Emily Aubrey, Laura D. Howe, Evie Stergiakouli, Santiago Rodriguez, Patricia M. Kearney, Linda M. O’Keeffe
Publikováno v:
O'Neill, K N, Aubrey, E, Howe, L D, Stergiakouli, E, Rodriguez, S, Kearney, P M & O'Keeffe, L M 2023, ' Mitochondrial DNA haplogroups and trajectories of cardiometabolic risk factors during childhood and adolescence : A prospective cohort study ', PLoS ONE, vol. 18, no. 4, e0284226 . https://doi.org/10.1371/journal.pone.0284226
Background Mitochondria are organelles responsible for converting glucose into energy. Mitochondrial DNA is exclusively maternally inherited. The role of mitochondrial DNA haplogroups in the aetiology of cardiometabolic disease risk is not well under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::988819509493c47fabe65f1b609206f9
https://hdl.handle.net/1983/2304c2f8-0814-4855-8895-d513001e82cb
https://hdl.handle.net/1983/2304c2f8-0814-4855-8895-d513001e82cb
Autor:
Sibelle T. Vilaça, Francesco Maroso, Paulo Lara, Benoit de Thoisy, Damien Chevallier, Larissa Souza Arantes, Fabricio R. Santos, Giorgio Bertorelle, Camila J. Mazzoni
This dataset contains ddRAD data used in our sea turtles genomics research on hybridization in Brazil. In this paper, we analyzed hybridization patterns, population structure and relatedness between southwest Atlantic population with a focus on Brazi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f1336fbe82f91c0c4cc61aeb3d8fcb
https://doi.org/10.1101/2022.10.10.511144
https://doi.org/10.1101/2022.10.10.511144
Autor:
Sophia Millington‐Ward, Naomi Chadderton, Laura K. Finnegan, Iris J.M. Post, Matthew Carrigan, Tom Gardiner, Elisa Peixoto, Daniel Maloney, Marian M. Humphries, Alan Stitt, Thierry Léveillard, Pete Humphries, Paul F. Kenna, Arpad Palfi, G. Jane Farrar
Publikováno v:
Clinical and Translational Medicine
Millington-Ward, S, Chadderton, N, Finnegan, L K, Post, I J M, Carrigan, M, Gardiner, T, Peixoto, E, Maloney, D, Humphries, M M, Stitt, A, Léveillard, T, Humphries, P, Kenna, P F, Palfi, A & Farrar, G J 2022, ' AAV-mediated gene therapy improving mitochondrial function provides benefit in age-related macular degeneration models ', Clinical and Translational Medicine, vol. 12, no. 8, e952 . https://doi.org/10.1002/ctm2.952
Millington-Ward, S, Chadderton, N, Finnegan, L K, Post, I J M, Carrigan, M, Gardiner, T, Peixoto, E, Maloney, D, Humphries, M M, Stitt, A, Léveillard, T, Humphries, P, Kenna, P F, Palfi, A & Farrar, G J 2022, ' AAV-mediated gene therapy improving mitochondrial function provides benefit in age-related macular degeneration models ', Clinical and Translational Medicine, vol. 12, no. 8, e952 . https://doi.org/10.1002/ctm2.952
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de0ba68887019dfd9054574032d5da9b
Autor:
Lee, R.G., Balasubramaniam, S., Stentenbach, M., Kralj, T., McCubbin, T., Padman, B., Smith, J., Riley, L.G., Priyadarshi, A., Peng, L.Y., Nuske, M.R., Webster, R., Peacock, K., Roberts, P., Stark, Z., Lemire, G., Ito, Y.A., Boycott, K.M., Geraghty, M.T., Klinken, J.B., Ferdinandusse, S., Zhou, Y., Walsh, R., Marcellin, E., Thorburn, D.R., Rosciolli, T., Fletcher, J., Rackham, O., Vaz, F.M., Reid, G.E., Filipovska, A., Care4Rare Canada Consortium
Publikováno v:
Human Molecular Genetics, 31(21), 3597-3612. OXFORD UNIV PRESS
Human molecular genetics, 31(21), 3597-3612. Oxford University Press
Human molecular genetics, 31(21), 3597-3612. Oxford University Press
Mitochondrial diseases are a group of inherited diseases with highly varied and complex clinical presentations. Here, we report four individuals, including two siblings, affected by a progressive mitochondrial encephalopathy with biallelic variants i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e79bac1d14fa395f9b21de73859fd0
https://pubmed.ncbi.nlm.nih.gov/36563328
https://pubmed.ncbi.nlm.nih.gov/36563328
Publikováno v:
Ji, J & Day, A 2020, ' Construction of a highly error-prone DNA polymerase for developing organelle mutation systems ', Nucleic Acids Res, vol. 48, no. 21, DOI: gkaa929, pp. 11868-11879 . https://doi.org/10.1093/nar/gkaa929
Nucleic Acids Research
Nucleic Acids Research
A novel family of DNA polymerases replicates organelle genomes in a wide distribution of taxa encompassing plants and protozoans. Making error-prone mutator versions of gamma DNA polymerases revolutionised our understanding of animal mitochondrial ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2dfc0f7a24dd32b9eaaa993c0d7130
http://www.narbreakthrough.com/2020/11/03/construction-of-a-highly-error-prone-dna-polymerase-for-developing-organelle-mutation-systems/
http://www.narbreakthrough.com/2020/11/03/construction-of-a-highly-error-prone-dna-polymerase-for-developing-organelle-mutation-systems/
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Recent studies associated certain type of cardiovascular disease (CVD) with specific mitochondrial DNA (mtDNA) defects, mainly driven by the central role of mitochondria in cellular metabolism. Considering the importance of the control region (CR) on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f33b38b921516b498b82211d75630eb3
http://europepmc.org/articles/PMC7026394
http://europepmc.org/articles/PMC7026394
Autor:
Kai Hell, Linda Liedgens, Alexandra Stiegler, Margarida Duarte, Maike Eberhardt, Marcel Deponte, Ulrike Wirth, Sandra Specht, Ana M. Tomás
Publikováno v:
Redox Biology, Vol 15, Iss C, Pp 363-374 (2018)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Redox Biology
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Redox Biology
Mia40/CHCHD4 and Erv1/ALR are essential for oxidative protein folding in the mitochondrial intermembrane space of yeast and mammals. In contrast, many protists, including important apicomplexan and kinetoplastid parasites, lack Mia40. Furthermore, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704b267b3ccb29bc65138df0ca39ab3c
http://www.sciencedirect.com/science/article/pii/S2213231717306456
http://www.sciencedirect.com/science/article/pii/S2213231717306456
Autor:
Bauke V. Schomakers, Nicole N. van der Wel, Rebecca L. McIntyre, Georges E. Janssens, Riekelt H. Houtkooper, Henk van der Veen, Ruedi Aebersold, Jiayi Lan, Pallas Yao, Alyson W. MacInnes, Evan G. Williams, Michel van Weeghel, William B. Mair, Yasmine J. Liu
Publikováno v:
Journal of cell biology, 219(6):e201907067.. Rockefeller University Press
The Journal of Cell Biology
The Journal of Cell Biology, 219 (6)
Journal of Cell Biology
The Journal of Cell Biology
The Journal of Cell Biology, 219 (6)
Journal of Cell Biology
Mitochondrial form and function are closely interlinked in homeostasis and aging. Inhibiting mitochondrial translation is known to increase lifespan in C. elegans, and is accompanied by a fragmented mitochondrial network. However, whether this link b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf92aa06dfb07ea906a8e597121f5502
http://orbilu.uni.lu/handle/10993/48043
http://orbilu.uni.lu/handle/10993/48043
Autor:
Silvana Miranda, Paula Boaventura, Marcelo Correia, Valdemar Máximo, Paula Soares, Ana Pestana, Jorge Lima, Anabela G. Dias, Joana B. Nunes
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Radiobiology is moving towards a better understanding of the intercellular signaling that occurs upon radiation and how its effects relate to the dose applied. The mitochondrial role in orchestrating this biological response needs to be further explo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e8b4746d968130829608d8c0d179fd
https://hdl.handle.net/10216/142511
https://hdl.handle.net/10216/142511
Autor:
Ana Luiza Dorigan de Matos Furlanetto, Kim H. Hebelstrup, Beatriz Ferrando, Jesper F. Havelund, Ian M. Møller, Tinna Stevnsner, Ricardo Gredilla
Publikováno v:
Ferrando, B, de Matos Furlanetto, A L D, Gredilla, R, Havelund, J F, Hebelstrup, K H, Møller, I M & Stevnsner, T 2019, ' DNA repair in plant mitochondria-A complete base excision repair pathway in potato tuber mitochondria ', Physiologia Plantarum, vol. 166, no. 2, pp. 494-512 . https://doi.org/10.1111/ppl.12801
Ferrando, B, Furlanetto, A L D M, Gredilla, R, Havelund, J F, Hebelstrup, K H, Møller, I M & Stevnsner, T 2019, ' DNA repair in plant mitochondria - a complete base excision repair pathway in potato tuber mitochondria ', Physiologia Plantarum, vol. 166, no. 2, pp. 494-512 . https://doi.org/10.1111/ppl.12801
Ferrando, B, Furlanetto, A L D M, Gredilla, R, Havelund, J F, Hebelstrup, K H, Møller, I M & Stevnsner, T 2019, ' DNA repair in plant mitochondria - a complete base excision repair pathway in potato tuber mitochondria ', Physiologia Plantarum, vol. 166, no. 2, pp. 494-512 . https://doi.org/10.1111/ppl.12801
Mitochondria are one of the major sites of reactive oxygen species (ROS) production in the plant cell. ROS can damage DNA, and this damage is in many organisms mainly repaired by the base excision repair (BER) pathway. We know very little about DNA r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac9f6048af023512b92f47ba8349682
https://findresearcher.sdu.dk:8443/ws/files/143374912/DNA_repair_in_plant_mitochondria_A_complete_base_excision_repair_pathway_in_potato_tuber_mitochondria.pdf
https://findresearcher.sdu.dk:8443/ws/files/143374912/DNA_repair_in_plant_mitochondria_A_complete_base_excision_repair_pathway_in_potato_tuber_mitochondria.pdf