Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mitja M Zdouc"'
Blocks in the pseudouridimycin pathway unlock hidden metabolites in the Streptomyces producer strain
Autor:
Marianna Iorio, Sahar Davatgarbenam, Stefania Serina, Paolo Criscenzo, Mitja M. Zdouc, Matteo Simone, Sonia I. Maffioli, Richard H. Ebright, Stefano Donadio, Margherita Sosio
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract We report a metabolomic analysis of Streptomyces sp. ID38640, a soil isolate that produces the bacterial RNA polymerase inhibitor pseudouridimycin. The analysis was performed on the wild type, on three newly constructed and seven previously
Externí odkaz:
https://doaj.org/article/bf5c6c742b4b4ec79d73fdd145693768
Autor:
Justin J.J. van der Hooft, Marnix H. Medema, Tilmann Weber, Tiago Leao, Jorge C. Navarro-Muñoz, Robin Schmid, Corinna Brungs, Mitja M. Zdouc, Barbara Terlouw, Paco Barona-Gómez, Cunliang Geng, Lindsay Caesar
These materials were used as a part of the NPLinker eScience Workshop on Natural Product Genome & Metabolome Mining:https://www.wur.nl/en/research-results/chair-groups/plant-sciences/bioinformatics/teaching/nplinker_workshop.htm Most materials are av
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1808703388bd77da7f6872e2b2a2d4f3
Autor:
Mitja M. Zdouc, Lina M. Bayona Maldonado, Hannah E. Augustijn, Sylvia Soldatou, Niek de Jonge, Marcel Jaspars, Gilles P. van Wezel, Marnix H. Medema, Justin J. J. van der Hooft
Small molecules can selectively modulate biological processes and thus generate phenotypic variation. Biological samples are complex matrices, and liquid chromatography tandem mass spectrometry often detects hundreds of molecules, of which only a fra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::887adcc60aa7fa88ec14b711444a4b6a
https://doi.org/10.1101/2022.12.21.521422
https://doi.org/10.1101/2022.12.21.521422
Autor:
Wiebke Hanke, Raphael Reher, Christa E. Müller, Evi Kostenis, Gabriele M. König, Jung Bong Kim, Stefan Kehraus, Max Crüsemann, Julian Patt, Judith Alenfelder, Vigneshwaran Namasivayam, Mitja M Zdouc, Goran Vuk Grujicic, Jan H. Voss
Publikováno v:
Journal of Natural Products. 84:1941-1953
Both the soil bacterium Chromobacterium vaccinii and the bacterial endosymbiont Candidatus Burkholderia crenata of the plant Ardisia crenata are producers of FR900359 (FR). This cyclic depsipeptide is a potent and selective Gq protein inhibitor used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09ecc71cfc0a46eaf6adf701be381175
https://doi.org/10.1021/acs.jnatprod.1c00194
https://doi.org/10.1021/acs.jnatprod.1c00194
Autor:
Guadalupe S. Zarazúa, Marianna Iorio, Arianna Tocchetti, Mitja M Zdouc, Margherita Sosio, Cristina Brunati, Matteo Simone, Stefania Serina, Kristiina Vind, Max Crüsemann, Paolo Monciardini, Stefano Donadio, Sonia I. Maffioli
Publikováno v:
Journal of Industrial Microbiology and Biotechnology
Journal of Industrial Microbiology and Biotechnology, 48(3-4)
Journal of Industrial Microbiology and Biotechnology 48 (2021) 3-4
Journal of Industrial Microbiology and Biotechnology, 48(3-4)
Journal of Industrial Microbiology and Biotechnology 48 (2021) 3-4
Natural products have provided many molecules to treat and prevent illnesses in humans, animals and plants. While only a small fraction of the existing microbial diversity has been explored for bioactive metabolites, tens of thousands of molecules ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e41e7f3c4b8d748c36a078b7fa82197
https://doi.org/10.1093/jimb/kuab017
https://doi.org/10.1093/jimb/kuab017
Blocks in the pseudouridimycin pathway unlock hidden metabolites in the Streptomyces producer strain
Autor:
Stefania Serina, Paolo Criscenzo, Richard H. Ebright, Sonia I. Maffioli, Marianna Iorio, Margherita Sosio, Stefano Donadio, Mitja M Zdouc, Sahar Davatgarbenam, Matteo Simone
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
We report a metabolomic analysis of Streptomyces sp. ID38640, a soil isolate that produces the bacterial RNA polymerase inhibitor pseudouridimycin. The analysis was performed on the wild type, on three newly constructed and seven previously reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8088e341e7f51d117040fcb18048d2cf
Autor:
Stefania Serina, Sonia I. Maffioli, Davatgarbenam S, Matteo Simone, Marianna Iorio, Mitja M Zdouc, Richard H. Ebright, Margherita Sosio, Stefano Donadio, Criscenzo P
Publikováno v:
BioRxiv
bioRxiv
bioRxiv
We report a metabolomic analysis of Streptomyces sp. ID38640, a soil isolate that produces the bacterial RNA polymerase inhibitor pseudouridimycin. The analysis was performed on the wild type and on ten different pum mutants blocked at different step
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22741053bec7faf9864d6e5c74c82865
https://doi.org/10.1101/2020.11.05.369249
https://doi.org/10.1101/2020.11.05.369249
Autor:
Mohammad Alanjary, Mitja M Zdouc, Margherita Sosio, Sonia I. Maffioli, Max Crüsemann, Marnix H. Medema, Stefano Donadio, Guadalupe S. Zarazúa
Microbial natural products impress by their bioactivity, structural diversity and ingenious biosynthesis. While screening the rare actinobacterial genus Planomonospora, cyclopeptides 1A and 1B were discovered, featuring an unusual Tyr-His biaryl-brid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ca44a2ccc8a477f64567c0a7866b5f4
https://doi.org/10.1101/2020.07.21.214643
https://doi.org/10.1101/2020.07.21.214643