Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mithun M. Shenoi"'
Autor:
John C. Bischof, Gregory J. Metzger, Isabelle Iltis, Manda L. Vollmers, Jeunghwan Choi, Mithun M. Shenoi
Publikováno v:
NMR in Biomedicine. 27:1063-1069
The outcome of systemic and local therapies (e.g. chemotherapy, radiotherapy, surgery, focal ablation) for prostate cancer can be significantly improved by using tumor-specific adjuvants prior to treatment ("preconditioning"). We propose to use dynam
Autor:
Paul A. Iaizzo, Matthew G. Geeslin, Erik N.K. Cressman, Leah Hennings, Yan Zhang, Theresa L. Edelman, John C. Bischof, Mithun M. Shenoi
Publikováno v:
International Journal of Hyperthermia. 28:105-112
To investigate simultaneous and sequential injection thermochemical ablation in a porcine model, and compare them to sham and acid-only ablation.This IACUC-approved study involved 11 pigs in an acute setting. Ultrasound was used to guide placement of
Autor:
Paul A. Iaizzo, John C. Bischof, Erik N.K. Cressman, Leah Hennings, Mithun M. Shenoi, Matthew G. Geeslin, Yan Zhang
Publikováno v:
International Journal of Hyperthermia. 28:113-121
To explore the effects of volume and concentration in thermochemical ablation using an in vivo porcine model.Twelve swine 60-75 kg were used in this institutionally approved study. A needle design prototype coaxial device for reagent injections and a
Autor:
Mithun M. Shenoi, Thishore Thekke-Adiyat, James Kyle Anderson, Renato N. Pedro, Joel W. Slaton, Raghav Goel, John C. Bischof, Steve Schmechel
Publikováno v:
Urology. 76:494-498
Objectives Radiofrequency ablation (RFA) has been most effective when the tumors are small, exophytic, and away from vital structures. We enlarged the size of the ablation kill zone by infusing a 30-nm tumor necrosis factor–α and polyethylene glyc
Autor:
Gregory J. Metzger, John C. Bischof, Nathan A. Koonce, Isabelle Iltis, Mithun M. Shenoi, Robert J. Griffin, Jeunghwan Choi
Surgery, radiation and chemotherapy remain the mainstay of current cancer therapy. However, treatment failure persists due to the inability to achieve complete local control of the tumor and curtail metastatic spread. Vascular disrupting agents (VDAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50565c6e579e442d1689bef7cb13c573
https://europepmc.org/articles/PMC3744664/
https://europepmc.org/articles/PMC3744664/
Nanoparticles show tremendous promise in the safe and effective delivery of molecular adjuvants to enhance local cancer therapy. One important form of local cancer treatment that suffers from local recurrence and distant metastases is thermal therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd8f506e070c21391a91be26b442686a
https://europepmc.org/articles/PMC3096482/
https://europepmc.org/articles/PMC3096482/
Publikováno v:
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2009
Thermal therapies such as hyperthermia, radiofrequency ablation, cryoablation, etc. have shown great potential and are gaining increasing clinical acceptance in the treatment of solid tumors. However, these treatment modalities are limited by the siz
Autor:
Mithun M. Shenoi, Stephen C. Schmechel, James E. Coad, Erin D. Grassl, Ramji T. Venkatasubramanian, John C. Bischof, Xiaoqing Zhang, Lenny George
Publikováno v:
ASME 2009 Summer Bioengineering Conference, Parts A and B.
Over 2 million adults in the United States are affected by atrial fibrillation (AF), a common cardiac arrhythmia that is associated with decreased survival, increased cardiovascular morbidities, and a decrease in quality of life. Atrial fibrillation
Autor:
Mithun M. Shenoi, Kyle Anderson, K. Thekke-Adiyat, Renato N. Pedro, Raghav Goel, Joel W. Slaton, Steve Schmechel, John C. Bischof
Publikováno v:
Journal of Medical Devices. 3
Thermal ablation therapies are currently used for the treatment of select renal masses. Such treatments are limited to tumors that are small (
Autor:
Erik N.K. Cressman, Mithun M. Shenoi
Publikováno v:
Journal of Medical Devices. 3
To overcome the limitations of existing ablation techniques, we propose a novel combinatorial approach that would utilize the thermal and chemical destructive effects of exothermic chemical reactions, such as an acid/base neutralization reaction, to