Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Mitchell Sun"'
Autor:
Herui Wang, Rogelio Medina, Juan Ye, Yaping Zhang, Samik Chakraborty, Alex Valenzuela, Ondrej Uher, Katerina Hadrava Vanova, Mitchell Sun, Xueyu Sang, Deric M. Park, Jan Zenka, Mark R. Gilbert, Karel Pacak, Zhengping Zhuang
Publikováno v:
Advanced Science, Vol 11, Iss 14, Pp n/a-n/a (2024)
Abstract Despite strides in immunotherapy, glioblastoma multiforme (GBM) remains challenging due to low inherent immunogenicity and suppressive tumor microenvironment. Converting “cold” GBMs to “hot” is crucial for immune activation and impro
Externí odkaz:
https://doaj.org/article/402be77c1897447c8a899980d3ead908
Autor:
Juan Ye, Herui Wang, Rogelio Medina, Samik Chakraborty, Mitchell Sun, Alex Valenzuela, Xueyu Sang, Yaping Zhang, Ondrej Uher, Jan Zenka, Karel Pacak, Zhengping Zhuang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-17 (2023)
Abstract Background Autologous tumor cell-based vaccines (ATVs) aim to prevent and treat tumor metastasis by activating patient-specific tumor antigens to induce immune memory. However, their clinical efficacy is limited. Mannan-BAM (MB), a pathogen-
Externí odkaz:
https://doaj.org/article/7abf8529748b422b80452f431e6eae1e
Autor:
Samik Chakraborty, Juan Ye, Herui Wang, Mitchell Sun, Yaping Zhang, Xueyu Sang, Zhengping Zhuang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Toll-like receptors (TLRs) are pattern recognition receptors (PRRs) expressed in various immune cell types and perform multiple purposes and duties involved in the induction of innate and adaptive immunity. Their capability to propagate immunity make
Externí odkaz:
https://doaj.org/article/cd4df9ed47114988a521888ff7c92ce1
Autor:
Chakraborty, Samik, Juan Ye, Herui Wang, Mitchell Sun, Yaping Zhang, Xueyu Sang, Zhengping Zhuang
Publikováno v:
Frontiers in Immunology; 2023, p1-19, 19p
Autor:
Juan Ye, Herui Wang, Mitchell Sun, Ondrej Uher, Mark R. Gilbert, Karel Pacak, Zhengping Zhuang, Rogelio Medina, Samik Chakraborty, Jan Zenka
Publikováno v:
Cancer Research. 83:6800-6800
Despite the advances made in cancer treatment over the past decades, one statistic has remained unchanged: metastatic cancer accounts for 90 percent of annual cancer deaths in the United States. Our group previously demonstrated that an autologous wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b837e98a729a618823651be3cf070c9
https://doi.org/10.1158/1538-7445.am2023-6800
https://doi.org/10.1158/1538-7445.am2023-6800
Autor:
Herui Wang, Rogelio Medina, Juan Ye, Samik Chakraborty, Ondrej Uher, Mitchell Sun, Jan Zenka, Mark R. Gilbert, Karel Pacak, Zhengping Zhuang
Publikováno v:
Cancer Research. 83:691-691
Despite numerous therapeutic advances in cancers, the treatment of glioblastoma multiforme (GBM) remains a challenge. Boosting T-lymphocyte mediated responses against GBM offers a promising approach towards solving this problem. Herein, we present a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab5105f356f3af49ae647a0468fd95dd
https://doi.org/10.1158/1538-7445.am2023-691
https://doi.org/10.1158/1538-7445.am2023-691
Autor:
Yulia Komarova, Kevin Kruse, Dianicha Santana, Fei Huang, Zhang Chen, Jeff Klomp, Pinal Kanabar, Mark Maienschein-Cline, Mitchell Sun
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Here we describe a novel method for studying the protein “interactome” in primary human cells and apply this method to investigate the effect of posttranslational protein modifications (PTMs) on the protein’s functions. We created a novel “bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11375ad4a005375c26b3e856ca66417b
https://doi.org/10.1152/ajplung.00392.2018
https://doi.org/10.1152/ajplung.00392.2018
Autor:
Yu Yao, Herui Wang, Chunxia Ji, Jared S. Rosenblum, Liemei Guo, Xiaoyu Cao, Dongqing Cao, Yang Wang, Zhengping Zhuang, Pauline Dmitriev, Kaiyong Yang, Mark R. Gilbert, Jing Cui, Qi Song, Iris H Indig, Qi Zhang, Mitchell Sun
Publikováno v:
Neuro Oncol
Background Glioblastoma survival remains unchanged despite continuing therapeutic innovation. Herein, we aim to (i) develop chimeric antigen receptor (CAR) T cells with a specificity to a unique antigen, carbonic anhydrase IX (CAIX), which is express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ab1c617350cf185fc06c254004155b
https://doi.org/10.1093/neuonc/noz117
https://doi.org/10.1093/neuonc/noz117
Autor:
Chen Xu, Pauline Dmitriev, Yang Wang, Mitchell Sun, Jingcheng Zhou, John S. Kovach, Zhengping Zhuang, Liemei Guo, Herui Wang, Mark R. Gilbert, Qi Song, Iris H Indig, Jared S. Rosenblum, Jing Cui, Qi Zhang, Rogelio Medina
Publikováno v:
Cancers
Volume 12
Issue 1
Cancers, Vol 12, Iss 1, p 139 (2020)
Volume 12
Issue 1
Cancers, Vol 12, Iss 1, p 139 (2020)
Chimeric antigen receptor (CAR)-engineered T cells represent a promising modality for treating glioblastoma. Recently, we demonstrated that CAR-T cells targeting carbonic anhydrase IX (CAIX), a protein involved in HIF-1a hypoxic signaling, is a promi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3540394cf88cc24aef6e22e85f09c68e
Autor:
Asrar B. Malik, Leon M. Tai, Jae-Won Shin, Fei Huang, Shuangping Zhao, Jeff Klomp, Zhigang Hong, Ying Sun, Quinn S. Lee, Xiaoyan Yang, Mitchell Sun, Stephen M. Vogel, Deborah E. Leckband, Kevin Kruse, Yulia Komarova
Publikováno v:
The Journal of Cell Biology
This work describes a role for endothelial N-cadherin in the regulation of endothelial permeability in the brain and lung. N-cadherin adhesions formed between endothelial cells and pericytes increase the abundance of VE-cadherin at adherens junctions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e0c6fc56f1f4058d8e76725d389353
https://doi.org/10.1083/jcb.201802076
https://doi.org/10.1083/jcb.201802076