Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mitchell S. Wold"'
Autor:
Nicole C McKnight, Yun Zhong, Mitchell S Wold, Shiaoching Gong, Greg R Phillips, Zhixun Dou, Yanxiang Zhao, Nathaniel Heintz, Wei-Xing Zong, Zhenyu Yue
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004626 (2014)
Deficiency of autophagy protein beclin 1 is implicated in tumorigenesis and neurodegenerative diseases, but the molecular mechanism remains elusive. Previous studies showed that Beclin 1 coordinates the assembly of multiple VPS34 complexes whose dist
Externí odkaz:
https://doaj.org/article/51ac15d136a3420aa4e5c1812c95eb5b
Publikováno v:
Trends in Cell Biology. 27:491-504
Previously thought of as a nonselective digestion process, autophagy is now known to specifically degrade aggregated proteins and damaged cellular organelles through the action of autophagy receptors, which provides cellular quality control and maint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8eaa9701910ec04207dc8be0c9ad852
https://doi.org/10.1016/j.tcb.2017.01.001
https://doi.org/10.1016/j.tcb.2017.01.001
Publikováno v:
Molecular Neurodegeneration
Background Autophagy is a bulk degradation pathway for long-lived proteins, protein aggregates, and damaged organelles. ULK1 protein kinase and Vps34 lipid kinase are two key autophagy regulators that are critical for autophagosome biogenesis. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c2530b1e27c894eb2fce4c4316a1d88
https://pubmed.ncbi.nlm.nih.gov/27938392
https://pubmed.ncbi.nlm.nih.gov/27938392
Autor:
Zhixun Dou, Greg R. Phillips, Nicole C. McKnight, Nathaniel Heintz, Yun Zhong, Mitchell S. Wold, Zhenyu Yue, Yanxiang Zhao, Shiaoching Gong, Wei-Xing Zong
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004626 (2014)
PLoS Genetics
PLoS Genetics
Deficiency of autophagy protein beclin 1 is implicated in tumorigenesis and neurodegenerative diseases, but the molecular mechanism remains elusive. Previous studies showed that Beclin 1 coordinates the assembly of multiple VPS34 complexes whose dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0ec043fcd25a4e346633cb746f179f
http://europepmc.org/articles/PMC4183436?pdf=render
http://europepmc.org/articles/PMC4183436?pdf=render