Zobrazeno 1 - 10
of 860
pro vyhledávání: '"Mitchell S. Cairo"'
Autor:
Wen Luo, Hai Hoang, Katherine E. Miller, Hongwen Zhu, Serena Xu, Xiaokui Mo, Elizabeth A. R. Garfinkle, Heather Costello, Saranga Wijeratne, Wiebke Chemnitz, Ronan Gandhi, Yanling Liao, Janet Ayello, Aliza Gardenswartz, Jeremy M. Rosenblum, Kevin A. Cassady, Elaine R. Mardis, Dean A. Lee, Timothy P. Cripe, Mitchell S. Cairo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-17 (2024)
Abstract Background Macrophages play important roles in phagocytosing tumor cells. However, tumors escape macrophage phagocytosis in part through the expression of anti-phagocytic signals, most commonly CD47. In Ewing sarcoma (ES), we found that tumo
Externí odkaz:
https://doaj.org/article/ef612054309d4f2fb16fbb5249bba11b
Autor:
Siddhi N. Paudel, Brian J. Hutzen, Katherine E. Miller, Elizabeth A. R. Garfinkle, Chun-Yu Chen, Pin-Yi Wang, Andrea M. Glaspell, Mark A. Currier, Emily M. Ringwalt, Louis Boon, Elaine R. Mardis, Mitchell S. Cairo, Nancy Ratner, Rebecca D. Dodd, Kevin A. Cassady, Timothy P. Cripe
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/aea62abb85594bdd81547a1e4aff9626
Autor:
Siddhi N. Paudel, Brian J. Hutzen, Katherine E. Miller, Elizabeth A. R. Garfinkle, Chun-Yu Chen, Pin-Yi Wang, Andrea M. Glaspell, Mark A. Currier, Emily M. Ringwalt, Louis Boon, Elaine R. Mardis, Mitchell S. Cairo, Nancy Ratner, Rebecca D. Dodd, Kevin A. Cassady, Timothy P. Cripe
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionMalignant peripheral nerve sheath tumors (MPNST) pose a significant therapeutic challenge due to high recurrence rates after surgical resection and a largely ineffective response to traditional chemotherapy. An alternative treatment strat
Externí odkaz:
https://doaj.org/article/30c6602860ac408d8659f1b13326bd9a
Autor:
Suzanne Braniecki, Elliott Vichinsky, Mark C. Walters, Shalini Shenoy, Qiuhu Shi, Theodore B. Moore, Julie-An Talano, Susan K. Parsons, Allyson Flower, Anne Panarella, Sandra Fabricatore, Erin Morris, Harshini Mahanti, Jordan Milner, Robert C. McKinstry, Christine N. Duncan, Carmella van de Ven, Mitchell S. Cairo
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundDue to the risk of cerebral vascular injury, children and adolescents with high-risk sickle cell disease (SCD) experience neurocognitive decline over time. Haploidentical stem cell transplantation (HISCT) from human leukocyte antigen-matche
Externí odkaz:
https://doaj.org/article/1ffd73bb5fe045e7b11a68a31f21a4a3
Autor:
Mitchell S. Cairo
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/d12f93ca2d6042169a0ac70cff51ba44
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The advent of novel cancer immunotherapy approaches is revolutionizing the treatment for cancer. Current small animal models for most cancers are syngeneic or genetically engineered mouse models or xenograft models based on immunodeficient mouse stra
Externí odkaz:
https://doaj.org/article/f402a5c130be44809bb32c4836fada52
Autor:
Morgan Anderson-Crannage, Alex M. Ascensión, Olga Ibanez-Solé, Hongwen Zhu, Edo Schaefer, Darcy Ottomanelli, Bruno Hochberg, Jian Pan, Wen Luo, Meijuan Tian, Yaya Chu, Mitchell S. Cairo, Ander Izeta, Yanling Liao
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Inflammation is known to play a critical role in all stages of tumorigenesis; however, less is known about how it predisposes the tissue microenvironment preceding tumor formation. Recessive dystrophic epidermolysis bullosa (RDEB), a skin-blistering
Externí odkaz:
https://doaj.org/article/34e1d4686234451eb208aeefa7d3b96f
Autor:
Yaya Chu, Julie-An Talano, Lee Ann Baxter-Lowe, James W. Verbsky, Erin Morris, Harshini Mahanti, Janet Ayello, Carolyn Keever-Taylor, Bryon Johnson, Rona S. Weinberg, Qiuhu Shi, Theodore B. Moore, Sandra Fabricatore, Brenda Grossman, Carmella van de Ven, Shalini Shenoy, Mitchell S. Cairo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionWe previously reported the initial results of a phase II multicenter transplant trial using haploidentical parental donors for children and aolescents with high-risk sickle cell disease achieving excellent survival with exceptionally low
Externí odkaz:
https://doaj.org/article/b0d0c172bee649e4b8a967bf44eea504
Autor:
Payal Aggarwal, Wen Luo, Katherine C. Pehlivan, Hai Hoang, Prajwal Rajappa, Timothy P. Cripe, Kevin A. Cassady, Dean A. Lee, Mitchell S. Cairo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
High grade gliomas are identified as malignant central nervous tumors that spread rapidly and have a universally poor prognosis. Historically high grade gliomas in the pediatric population have been treated similarly to adult high grade gliomas. For
Externí odkaz:
https://doaj.org/article/59aa2ba0d016490c89b1120c5578edcc
Autor:
Brian Hutzen, Mohammed Ghonime, Joel Lee, Elaine R. Mardis, Ruoning Wang, Dean A. Lee, Mitchell S. Cairo, Ryan D. Roberts, Timothy P. Cripe, Kevin A. Cassady
Publikováno v:
Molecular Therapy: Oncolytics, Vol 15, Iss , Pp 38-48 (2019)
Solid tumors contain a mixture of malignant cells and non-malignant infiltrating cells that often create a chronic inflammatory and immunosuppressive microenvironment that restricts immunotherapeutic approaches. Although childhood and adult cancers s
Externí odkaz:
https://doaj.org/article/36af620670ea4aae9d7d981fa9e79e75