Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mitchell R. Clarke"'
Autor:
Mitchell R. Clarke, Sarah K. Baird, D. Tim Harwood, Floriane M. Imhoff, Andrew I. Selwood, Lesley Rhodes, Ben Jones, Chloe L M Squires, Paul McNabb
Publikováno v:
Journal of Natural Products. 84:2035-2042
Pinnatoxin G is a cyclic imine neurotoxin produced by dinoflagellates that has been reported in shellfish. Like other members of the pinnatoxin family, it has been shown to have its effects via antagonism of the nicotinic acetylcholine receptors, wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e4d5c80d51e9e177f0b20d321202e6b
https://doi.org/10.1021/acs.jnatprod.1c00418
https://doi.org/10.1021/acs.jnatprod.1c00418
Autor:
April C Braddy, Arno Nolting, Gustavo Mendes Lima Santos, Sang Aeh Park, Yusuke Okada, Wen-Yi Hung, Mitchell R. Clarke, Alfredo Garcia Arieta, Chantal Pfäffli, Joy Van Oudtshoorn, Christopher Crane, Ji Myoung Kim, Ryosuke Kuribayashi, Zulema Rodríguez Martínez, Clare Rodrigues, Craig Simon, Iván Omar Calderón Lojero, Diego Alejandro Gutierrez Triana
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 22, Iss 1 (2019)
The acceptance of foreign comparator products is the most limiting factor for the development and regulatory assessment of generic medicines marketed globally. Bioequivalence studies have to be repeated with the local comparator products of each juri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c87d25c0eeae53e1160b6dc174a4204
https://pubmed.ncbi.nlm.nih.gov/30599818
https://pubmed.ncbi.nlm.nih.gov/30599818
Publikováno v:
Molecular Carcinogenesis. 54:1214-1219
Mesenchymal stem cells (MSCs) form part of tumor stroma, and are typically considered to be pro-tumorigenic, promoting continuing tumor growth and metastasis. Here, we describe a mechanism by which MSCs may be anti-tumorigenic, through inhibition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5db9f093fabc68fdb33c8dd24c7552d
https://doi.org/10.1002/mc.22178
https://doi.org/10.1002/mc.22178
Autor:
Arno Nolting, Peter Bachmann, Iván Omar Calderón Lojero, Diego Alejandro Gutierrez Triana, Wen-Yi Hung, April C Braddy, Craig Simon, Nancy Arciniegas Leal, Ji Myoung Kim, Gustavo Mendes Lima Santos, Joy Van Oudtshoorn, Ryosuke Kuribayashi, Yusuke Okada, Christopher Crane, Mitchell R. Clarke, Sang Aeh Park, Zulema Rodríguez Martínez, Chantal Pfäffli, Clare Rodrigues, Alfredo García-Arieta
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 21 (2018)
Purpose: The Biopharmaceutics Classification System (BCS) based biowaiver is a scientific model which enables the substitution of in vivo bioequivalence studies with in vitro data as evidence of therapeutic equivalence subject to certain conditions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc15358b0a25116fd9678144d20b50b
https://doi.org/10.18433/j3x93k
https://doi.org/10.18433/j3x93k
Publikováno v:
Molecular carcinogenesis. 54(10)
Mesenchymal stem cells (MSCs) form part of tumor stroma, and are typically considered to be pro-tumorigenic, promoting continuing tumor growth and metastasis. Here, we describe a mechanism by which MSCs may be anti-tumorigenic, through inhibition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a052248a95548bee381145f4658b47fa
https://pubmed.ncbi.nlm.nih.gov/24819588
https://pubmed.ncbi.nlm.nih.gov/24819588