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pro vyhledávání: '"Mitchell Lavarias"'
Assessment of Human Renal Transporter Based Drug-Drug Interactions Using Proximal Tubule Kidney-Chip
Autor:
Anantha Ram Nookala, Janey Ronxhi, Josiah Sliz, Sauvear Jeanty, Dimitris V. Manatakis, Sushma Jadalannagari, Geraldine Hamilton, Hyoungshin Park, Yu He, Mitchell Lavarias, Gang Luo, Kyung-Jin Jang, Donald Mckenzie
Study of renal transporters is crucial for understanding drug disposition and toxicity, and more importantly, predicting potential drug-drug interactions (DDIs). However, conventional in vitro models often fail to predict renal transporter activity a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddeac2c41070191c706604d26329663f
https://doi.org/10.1101/2022.05.12.491717
https://doi.org/10.1101/2022.05.12.491717
Autor:
Eric V. Campbell, Mitchell Lavarias, Claire Stewart, Kolyn Morris, Matthew J. Gage, Rachel Hendrix, Shauna Nichol, Wai Kit Ma
Intrinsically disordered proteins (IDPs) are a unique class of proteins that do not require a stable structure for function. The importance of IDPs in many biological processes has been established but there remain unanswered questions about their ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c23887a48ab2703664be531b3f02b71
https://europepmc.org/articles/PMC3650836/
https://europepmc.org/articles/PMC3650836/