Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Mitchell F, Denning"'
Publikováno v:
Oral Oncology Reports, Vol 5, Iss , Pp 100008- (2023)
Externí odkaz:
https://doaj.org/article/c2eab0ec4f0647d68998c22a7310efee
Autor:
Hao Wang, Wei Hou, Aldeb Perera, Carlee Bettler, Jordan R. Beach, Xianzhong Ding, Jun Li, Mitchell F. Denning, Asha Dhanarajan, Scott J. Cotler, Cara Joyce, Jun Yin, Fowsiyo Ahmed, Lewis R. Roberts, Wei Qiu
Publikováno v:
Cell Reports, Vol 34, Iss 8, Pp 108765- (2021)
Summary: Hepatocellular carcinoma (HCC) remains one of the deadliest malignancies worldwide. One major obstacle to treatment is a lack of effective molecular-targeted therapies. In this study, we find that EphA2 expression and signaling are enriched
Externí odkaz:
https://doaj.org/article/5490c094d7e84abdba870ac14d82cd3c
Autor:
Lei Zhang, Huacheng Luo, Hong-Min Ni, Shanhui Liu, Hongyun Xing, Jun Zhang, Mark Sellin, Peter Breslin, S.J., Wei Wei, Mitchell F. Denning, William Small, Wen-Xing Ding, Suming Huang, Jiwang Zhang
Publikováno v:
Stem Cell Reports. 17:1428-1441
Receptor-interacting protein kinase 3 (Ripk3) is one of the critical mediators of inflammatory cytokine-stimulated signaling. Here we show that Ripk3 signaling selectively regulates both the number and the function of hematopoietic stem cells (HSCs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8722b7d1cd552296a7a18d8f53eab137
https://doi.org/10.1016/j.stemcr.2022.04.009
https://doi.org/10.1016/j.stemcr.2022.04.009
Autor:
Clodia Osipo, Mitchell F. Denning, Lucio Miele, Kathy S. Albain, Ajay Rana, Jason Sagert, Aleksandra Filipovic, Ian O. Ellis, Andrew Green, Antonio Pannuti, Andrei Zlobin, Jeffrey Bloodworth, Andrew Baker, Deep Shah, Brian Gallagher, Debra Wyatt, Kinnari Pandya
Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9378849a58b9c3ece51074b4bc667d08
https://doi.org/10.1158/1078-0432.22461047.v1
https://doi.org/10.1158/1078-0432.22461047.v1
Autor:
Clodia Osipo, Mitchell F. Denning, Lucio Miele, Kathy S. Albain, Ajay Rana, Jason Sagert, Aleksandra Filipovic, Ian O. Ellis, Andrew Green, Antonio Pannuti, Andrei Zlobin, Jeffrey Bloodworth, Andrew Baker, Deep Shah, Brian Gallagher, Debra Wyatt, Kinnari Pandya
A. Mib-1 is required for trastuzumab or lapatinib-induced increase of HES-1 protein expression in MDA-MB-453 cells. B. Notch-1, JAG-1, and HES-1 proteins are increases in trastuzumab resistant BT474 cells compared to sensitive cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::270a5a3e0c2a9dadade7cc15fc21e6f0
https://doi.org/10.1158/1078-0432.22461056
https://doi.org/10.1158/1078-0432.22461056
Autor:
Clodia Osipo, Mitchell F. Denning, Lucio Miele, Kathy S. Albain, Ajay Rana, Jason Sagert, Aleksandra Filipovic, Ian O. Ellis, Andrew Green, Antonio Pannuti, Andrei Zlobin, Jeffrey Bloodworth, Andrew Baker, Deep Shah, Brian Gallagher, Debra Wyatt, Kinnari Pandya
Purpose: Breast cancer is the second leading cause of cancer mortality among women worldwide. The major problem with current treatments is tumor resistance, recurrence, and disease progression. ErbB-2–positive breast tumors are aggressive and frequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168bb3655ef2813a161023030cb3d450
https://doi.org/10.1158/1078-0432.c.6524684.v1
https://doi.org/10.1158/1078-0432.c.6524684.v1
Publikováno v:
Journal of Skin Cancer, Vol 2013 (2013)
Externí odkaz:
https://doaj.org/article/f47f0e5284d043619b05e191b2a88ecc
Autor:
Anthony J. Koleske, Thomas Bank, Wei Hou, Lennox Chitsike, Fang Wang, Mitchell F. Denning, Scott J. Cotler, Aldeb Perera, Xianzhong Ding, Jun Li, Peter Breslin, Wei Qiu, Wenan Qiang, Carlee Bettler, Yingchen Xu, Asha Dhanarajan
Publikováno v:
Gastroenterology
BACKGROUND & AIMS: We investigated whether ABL proto-oncogene 1, non-receptor tyrosine kinase (ABL1) is involved in development of hepatocellular carcinoma (HCC). METHODS: We analyzed clinical and gene expression data from The Cancer Genome Atlas. Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8e10d4909e258f3867fbcabf216748
https://doi.org/10.1053/j.gastro.2020.03.013
https://doi.org/10.1053/j.gastro.2020.03.013
Autor:
Geun-Hyoung Ha, Shiaw Yih Lin, Loredana Campo, Mitchell F. Denning, Eun Kyoung Breuer, Clodia Osipo, Tarun B. Patel, Jung Lye Kim
Publikováno v:
Oncotarget
BRCA1 is an important player in the DNA damage response signaling, and its deficiency results in genomic instability. A complete loss or significantly reduced BRCA1 protein expression is often found in sporadic breast cancer cases despite the absence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439caa1feff2bddcb093f3c4a4945396
https://doi.org/10.18632/oncotarget.5717
https://doi.org/10.18632/oncotarget.5717
Autor:
Philip M. Roper, Jiwang Zhang, Matthew A.C. Zapf, Mitchell F. Denning, Philip Y. Wai, John J. Callaci, Joseph Driver, Gopal N. Gupta, Paul C. Kuo, Anai N. Kothari, Carrie A. Franzen, Zhiyong Mi, Dariusz Borys, Cynthia E. Weber
Publikováno v:
Journal of Biological Chemistry. 290:9959-9973
Alcohol (EtOH) intoxication is a risk factor for increased morbidity and mortality with traumatic injuries, in part through inhibition of bone fracture healing. Animal models have shown that EtOH decreases fracture callus volume, diameter, and biomec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f305d25b3b0b4eab3d3570e63d20ef8d
https://doi.org/10.1074/jbc.m114.616888
https://doi.org/10.1074/jbc.m114.616888