Zobrazeno 1 - 10
of 434
pro vyhledávání: '"Mitchell Dowsett"'
Autor:
Vanessa Almendro, Yu-Kang Cheng, Amanda Randles, Shalev Itzkovitz, Andriy Marusyk, Elisabet Ametller, Xavier Gonzalez-Farre, Montse Muñoz, Hege G. Russnes, Åslaug Helland, Inga H. Rye, Anne-Lise Borresen-Dale, Reo Maruyama, Alexander van Oudenaarden, Mitchell Dowsett, Robin L. Jones, Jorge Reis-Filho, Pere Gascon, Mithat Gönen, Franziska Michor, Kornelia Polyak
Publikováno v:
Cell Reports, Vol 6, Iss 3, Pp 514-527 (2014)
Cancer therapy exerts a strong selection pressure that shapes tumor evolution, yet our knowledge of how tumors change during treatment is limited. Here, we report the analysis of cellular heterogeneity for genetic and phenotypic features and their sp
Externí odkaz:
https://doaj.org/article/9aab389303f9453b895d7dc845938253
Autor:
Deborah J. Thompson, Douglas F. Easton, Mitchell Dowsett, Ruth M.L. Warren, Tina Audley, Jean Leyland, Judith Brown, Elizabeth Folkerd, Paula L. Smith, Jajini S. Varghese
PDF file - 108K, Regression estimates for associations between density measures and risk factors in the SIBS cohort.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5e2e446ff5fa7dec2db8fb19fe2d2e
https://doi.org/10.1158/1055-9965.22435659.v1
https://doi.org/10.1158/1055-9965.22435659.v1
Autor:
Mitchell Dowsett, Adrian L. Harris, Ian E. Smith, Janine Salter, Simone Detre, Tim Dexter, Helen Anderson, Anita K. Dunbier, Francesca M. Buffa, Zara Ghazoui
Purpose: The majority of breast cancer patients who have estrogen receptor positive (ER+) tumors whose proliferation is reduced after estrogen deprivation by aromatase inhibitors (AI). This study investigates any link between proliferation and hypoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b405459bf5288588174f4eac3a28b72
https://doi.org/10.1158/1078-0432.c.6518916.v1
https://doi.org/10.1158/1078-0432.c.6518916.v1
Autor:
Lesley-Ann Martin, Mitchell Dowsett, Dean B. Evans, Amanda J. Littlewood-Evans, Simone Detre, Roger A'Hern, Susana Banerjee
Supplementary Figure S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eab65d673ea715831407efdf50e1522
https://doi.org/10.1158/1078-0432.22442943.v1
https://doi.org/10.1158/1078-0432.22442943.v1
Autor:
D. Gareth Evans, Judith Adams, Jamie C. Sergeant, Jamie Motion, Caroline Boggis, Rosemary Greenhalgh, Jack M. Cuzick, Mitchell Dowsett, Adam R. Brentnall, Ann Ward, Rosalind A. Eeles, Diana M. Eccles, Lesley Fallowfield, Linda Ashcroft, Anthony Howell
Supplementary Table 1. DXA scan measurements (Baseline, 1-yr and 2-yr.)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::442a6e8770802f25a92408dd420027c4
https://doi.org/10.1158/1055-9965.22437112.v1
https://doi.org/10.1158/1055-9965.22437112.v1
Autor:
Deborah J. Thompson, Douglas F. Easton, Mitchell Dowsett, Ruth M.L. Warren, Tina Audley, Jean Leyland, Judith Brown, Elizabeth Folkerd, Paula L. Smith, Jajini S. Varghese
Background: Mammographic breast density and endogenous sex-hormone levels are both strong risk factors for breast cancer. This study investigated whether there is evidence for a shared genetic basis between these risk factors.Methods: Using data on 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17805c01d38f5f47d0b51ec8ddc49376
https://doi.org/10.1158/1055-9965.c.6515040.v1
https://doi.org/10.1158/1055-9965.c.6515040.v1
Autor:
Mitchell Dowsett, Adrian L. Harris, Ian E. Smith, Janine Salter, Simone Detre, Tim Dexter, Helen Anderson, Anita K. Dunbier, Francesca M. Buffa, Zara Ghazoui
Supplementary Figure S1; Supplementary Tables S1-S6.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab7d9a288312aadeb6af76d40cab4955
https://doi.org/10.1158/1078-0432.22442094.v1
https://doi.org/10.1158/1078-0432.22442094.v1
Autor:
Deborah J. Thompson, Douglas F. Easton, Mitchell Dowsett, Ruth M.L. Warren, Tina Audley, Jean Leyland, Judith Brown, Elizabeth Folkerd, Paula L. Smith, Jajini S. Varghese
PDF file - 109K, Regression estimates for associations between sex-hormone measures and risk factors in the SIBS cohort.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194e34fe56753f60a39fca78b55e66c1
https://doi.org/10.1158/1055-9965.22435656
https://doi.org/10.1158/1055-9965.22435656
Autor:
D. Gareth Evans, Judith Adams, Jamie C. Sergeant, Jamie Motion, Caroline Boggis, Rosemary Greenhalgh, Jack M. Cuzick, Mitchell Dowsett, Adam R. Brentnall, Ann Ward, Rosalind A. Eeles, Diana M. Eccles, Lesley Fallowfield, Linda Ashcroft, Anthony Howell
Background: Ovarian suppression in premenopausal women is known to reduce breast cancer risk. This study aimed to assess uptake and compliance with ovarian suppression using the luteinizing hormone releasing hormone (LHRH) analogue, goserelin, with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::077ab0b45dce31b97744b693969810c3
https://doi.org/10.1158/1055-9965.c.6515731
https://doi.org/10.1158/1055-9965.c.6515731
Autor:
Lesley-Ann Martin, Mitchell Dowsett, Dean B. Evans, Amanda J. Littlewood-Evans, Simone Detre, Roger A'Hern, Susana Banerjee
Purpose: Targeting vascular endothelial growth factor (VEGF) and estrogen receptor signaling pathways concomitantly may enhance benefit in estrogen receptor–positive breast cancer. We had shown previously that the VEGF receptor tyrosine kinase inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48abf36b6cc24c30d787d847a6311a02
https://doi.org/10.1158/1078-0432.c.6519564
https://doi.org/10.1158/1078-0432.c.6519564