Zobrazeno 1 - 10
of 171
pro vyhledávání: '"Mitchell B. Schaffler"'
Autor:
Manisha Dixit, Zhongbo Liu, Sher Bahadur Poudel, Gozde Yildirim, Yanjiao Zhang Zhang, Shilpa Mehta, Omer Murik, Geona Altarescu, Yoshifumi Kobayashi, Emi Shimizu, Mitchell B. Schaffler, Shoshana Yakar
Publikováno v:
JBMR Plus, Vol 5, Iss 5, Pp n/a-n/a (2021)
ABSTRACT Patients with type 1 diabetes mellitus (T1DM) exhibit reduced BMD and significant increases in fracture risk. Changes in BMD are attributed to blunted osteoblast activity and inhibited bone remodeling, but these cannot fully explain the impa
Externí odkaz:
https://doaj.org/article/c5cdf96ce96e4b9a81953f785af6e4aa
Autor:
Daniel J. Leong, Marwa Choudhury, Regina Hanstein, David M. Hirsh, Sun Jin Kim, Robert J. Majeska, Mitchell B. Schaffler, John A. Hardin, David C. Spray, Mary B. Goldring, Neil J. Cobelli, Hui B. Sun
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-1 (2019)
Following publication of the original article [1], the authors reported an error in Figs. 2C and 5C.
Externí odkaz:
https://doaj.org/article/11a1159e8a124267a7828f7eb828308e
Autor:
Manisha Dixit, Leeann D Louis, Jelena Basta‐Pljakic, Gozde Yildirim, Sher‐Bahadur Poudel, Fancy Kumararaja, Edward O List, Silvana Ortiz Duran, John J Kopchick, Ryan R Ruff, Mitchell B Schaffler, Shoshana Yakar
Publikováno v:
Journal of Bone and Mineral Research. 37:2201-2214
Excess in growth hormone (GH) levels, seen in patients with acromegaly, is associated with increases in fractures. This happens despite wider bones and independent of bone mineral density. We used the bovine GH (bGH) transgenic mice, which show const
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::955895b236900b51d4e5c174af8ce682
https://doi.org/10.1002/jbmr.4699
https://doi.org/10.1002/jbmr.4699
Autor:
Mitchell B. Schaffler, Mia M. Thi, David C. Spray, Macy Castaneda, James F. Boorman-Padgett, Karl J. Lewis
Publikováno v:
Journal of Visualized Experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c50a5d6e03a2936a204c31390247fde3
https://doi.org/10.3791/64366
https://doi.org/10.3791/64366
Autor:
null Manisha Dixit, null Leeann D Louis, null Jelena Basta‐Pljakic, null Gozde Yildirim, null Sher‐Bahadur Poudel, null Fancy Kumararaja, null Edward O List, null Silvana Ortiz Duran, null John J Kopchick, null Ryan R Ruff, null Mitchell B Schaffler, null Shoshana Yakar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b2f0311b0a3c28b35b269be88668f3f
https://doi.org/10.1002/jbmr.4699/v4/response1
https://doi.org/10.1002/jbmr.4699/v4/response1
Autor:
Leeann D. Louis, Shoshana Yakar, Mitchell B. Schaffler, Godze Yildirim, Manisha Dixit, John J. Kopchick, Andrzej Bartke, Silvana Duran-Ortiz, Sher Bahadur Poudel
Publikováno v:
Aging Cell
Somatopause refers to the gradual declines in growth hormone (GH) and insulin‐like growth factor‐1 throughout aging. To define how induced somatopause affects skeletal integrity, we used an inducible GH receptor knockout (iGHRKO) mouse model. Som
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b25a3d93ce66a007e37b4ed8f8c8554a
https://doi.org/10.1111/acel.13505
https://doi.org/10.1111/acel.13505
Autor:
Abigail A Coffman, Jelena Basta‐Pljakic, Rosa M Guerra, Frank H Ebetino, Mark W Lundy, Robert J Majeska, Mitchell B Schaffler
Publikováno v:
JBMR Plus, Vol 5, Iss 7, Pp n/a-n/a (2021)
JBMR Plus
JBMR Plus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa45e74c46907cda035bef3123f5ad9
https://doaj.org/article/39b83b895613419fbd0d9763b0efaee3
https://doaj.org/article/39b83b895613419fbd0d9763b0efaee3
Autor:
Emi Shimizu, Manisha Dixit, Mitchell B. Schaffler, Omer Murik, Gozde Yildirim, Zhongbo Liu, Shilpa Mehta, Yoshifumi Kobayashi, Yanjiao Zhang Zhang, Shoshana Yakar, Sher Bahadur Poudel, Geona Altarescu
Publikováno v:
JBMR Plus, Vol 5, Iss 5, Pp n/a-n/a (2021)
JBMR Plus
JBMR Plus
Patients with type 1 diabetes mellitus (T1DM) exhibit reduced BMD and significant increases in fracture risk. Changes in BMD are attributed to blunted osteoblast activity and inhibited bone remodeling, but these cannot fully explain the impaired bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ac3bdc8e45a2db5794354589d4eac8
https://doi.org/10.1002/jbm4.10483
https://doi.org/10.1002/jbm4.10483
Autor:
Rosa M Guerra, Robert J. Majeska, Abigail A Coffman, Mitchell B. Schaffler, Mark W Lundy, Jelena Basta-Pljakic, Frank H. Ebetino
Publikováno v:
JBMR Plus, Vol 5, Iss 4, Pp n/a-n/a (2021)
JBMR Plus
JBMR Plus
Bisphosphonates (BPs) are a mainstay of osteoporosis treatment; however, concerns about bone health based on oversuppression of remodeling remain. Long‐term bone remodeling suppression adversely affects bone material properties with microdamage acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80297482979bcf35bdd0d3bf4438820b
https://doi.org/10.1002/jbm4.10476
https://doi.org/10.1002/jbm4.10476
Autor:
Shoshana Yakar, Andrey Y. Abramov, Clifford J. Rosen, Haim Werner, Evgeny Pavlov, Dorra Frikha-Benayed, Maria E. Solesio, Mitchell B. Schaffler, Zhongbo Liu, John J. Kopchick
Publikováno v:
Journal of Bone and Mineral Research. 34:106-122
Despite increased longevity and resistance to multiple stressors, growth hormone receptor null (GHRKO) mice exhibit severe skeletal impairment. The role of GHR in maintaining osteocyte mitochondrial function is unknown. We found that GHR ablation was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a442f587ab38d1e422acbc25f6db9ba2
https://doi.org/10.1002/jbmr.3573
https://doi.org/10.1002/jbmr.3573