Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Mitchell B. Rosen"'
Autor:
Mitchell B. Rosen, Judith R. Schmid, J. Christopher Corton, Robert D. Zehr, Kaberi P. Das, Barbara D. Abbott, Christopher Lau
Publikováno v:
PPAR Research, Vol 2010 (2010)
Perfluorooctane sulfonate (PFOS) is a perfluoroalkyl acid (PFAA) and a persistent environmental contaminant found in the tissues of humans and wildlife. Although blood levels of PFOS have begun to decline, health concerns remain because of the long h
Externí odkaz:
https://doaj.org/article/4bfde09e4e3a4715ba1775582c2a65fc
Publikováno v:
Birth Defects Research. 110:35-47
BACKGROUND ATP binding cassette sub-family member 2 (ABCG2) is a well-defined efflux transporter found in a variety of tissues. The role of ABCG2 during early embryonic development, however, is not established. Previous work which compared data from
Autor:
Andrew B. Lindstrom, R. Daniel Zehr, Kaberi P. Das, Brian E. Grey, Carmen R. Wood, Christopher Lau, Mitchell B. Rosen, Katoria Tatum-Gibbs, Mark J. Strynar
Publikováno v:
Reproductive Toxicology. 51:133-144
Perfluorononanoic acid (PFNA) is a ubiquitous and persistent environmental contaminant. Although its levels in the environment and in humans are lower than those of perfluorooctane sulfonate (PFOS) or perfluorooctanoic acid (PFOA), a steady trend of
Autor:
Barbara D. Abbott, Mitchell B. Rosen, Christopher Lau, J. Christopher Corton, John P. Rooney, Kaberi P. Das
Publikováno v:
Toxicology. 387
Perfluoroalkyl acids (PFAAs) are ubiquitous and persistent environmental contaminants. Compounds such as perfluoroocanoic acid (PFOA), perfluorooctane sulfonate (PFOS), perfluorononanoic acid (PFNA), and perfluorohexane sulfonate (PFHxS) are readily
Autor:
M. I. Gage, Judith E. Schmid, Y. Liu, Ellen H. Rogers, Christopher A. Bradfield, Richard H. Jaskot, Carmen R. Wood, Mitchell B. Rosen, J. H. Richards, David E. Malarkey, Robert D. Zehr, Neil Chernoff
Publikováno v:
Journal of Applied Toxicology. 31:242-254
Cylindrospermopsin (CYN) is a tricyclic alkaloid toxin produced by fresh water cyanobacterial species worldwide. CYN has been responsible for both livestock and human poisoning after oral exposure to CYN. This study investigated the toxicity of CYN t
Autor:
Mitchell B. Rosen, Carmen R. Wood, Judith E. Schmid, Christopher Lau, Robert D. Zehr, Kaberi P. Das
Publikováno v:
Reproductive Toxicology. 27:278-288
Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) are environmental contaminants found in the tissues of humans and wildlife. They are activators of peroxisome proliferator-activated receptor-alpha (PPAR alpha) and exhibit hepatocarc
Autor:
Hongzu Ren, J. Christopher Corton, Janice S. Lee, Jie Liu, Christopher Lau, Mitchell B. Rosen, Beena Vallanat, Michael P. Waalkes, Barbara D. Abbott
Publikováno v:
Toxicological Sciences. 103:46-56
A number of perfluorinated alkyl acids including perfluorooctanoic acid (PFOA) elicit effects similar to peroxisome proliferator chemicals (PPC) in mouse and rat liver. There is strong evidence that PPC cause many of their effects linked to liver can
Autor:
Gary A. Held, Neil Chernoff, Mitchell B. Rosen, Bettina M Francis, Stacy Branch, Cecil F. Brownie
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 12:135-141
5-Aza-2′-deoxycytidine (d-AZA) inhibits methylation of DNA, a process that serves as an epigenetic regulator of gene expression. We have shown that d-AZA causes temporally related defects in mice. Gestational day (GD) 10 treatment induced severe lo
Autor:
Carmen R. Wood, Cynthia J. Wolf, Kaberi P. Das, Mitchell B. Rosen, Christopher Lau, Barbara D. Abbott
Publikováno v:
Toxicology. 308
While perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) have been studied at length, less is known about the biological activity of other perfluoroalkyl acids (PFAAs) detected in the environment. Using a transient transfection assay
Autor:
Mary C. Cardon, Clinton Y. Kawanishi, Phillip C. Hartig, Judith E. Schmid, Mitchell B. Rosen, Neil Chernoff
Publikováno v:
Toxicology Methods. 6:13-22
Alteration of gene expression can result in numerous pathologies, including proliferative diseases, functional deficits, and developmental defects. Recent studies have suggested that changes in the expression domains of Homeotic (Hox) genes during de