Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mitchell Acland"'
Autor:
Witchuda Sukjoi, Clifford Young, Mitchell Acland, Siraprapa Siritutsoontorn, Sittiruk Roytrakul, Manuela Klingler-Hoffmann, Peter Hoffmann, Sarawut Jitrapakdee
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2024)
We have previously shown that the holocarboxylase synthetase (HLCS) is overexpressed in breast cancer tissue of patients, and silencing of its expression in triple-negative cancer cell line inhibits growth and migration. Here we investigated the glob
Externí odkaz:
https://doaj.org/article/ccc46b5c288642bfacc936eead76a1e5
Autor:
Mitchell Acland, Parul Mittal, Georgia Arentz, Fergus Whitehead, Peter Hoffmann, Manuela Klingler-Hoffmann, Martin K. Oehler
Publikováno v:
Methods and Protocols, Vol 5, Iss 4, p 57 (2022)
The molecular analysis of small or rare patient tissue samples is challenging and often limited by available technologies and resources, such as reliable antibodies against a protein of interest. Although targeted approaches provide some insight, her
Externí odkaz:
https://doaj.org/article/679e2b6fdedc4bcdba832f3e9d2ba2b0
Autor:
Mitchell Acland, Georgia Arentz, Max Mussared, Fergus Whitehead, Peter Hoffmann, Manuela Klingler-Hoffmann, Martin K. Oehler
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Serous endometrial cancer (SEC) and high grade serous ovarian cancer (HGSOC) are aggressive gynecological malignancies with high rates of metastasis and poor prognosis. Endometrial intraepithelial carcinoma (EIC), the precursor for SEC, and serous tu
Externí odkaz:
https://doaj.org/article/08ff05f4f0c1401fbea2e78c98ae29ab
Autor:
Mitchell Acland, Noor A. Lokman, Clifford Young, Dovile Anderson, Mark Condina, Chris Desire, Tannith M. Noye, Wanqi Wang, Carmela Ricciardelli, Darren J. Creek, Martin K. Oehler, Peter Hoffmann, Manuela Klingler-Hoffmann
Publikováno v:
Cancers; Volume 14; Issue 11; Pages: 2763
Chemoresistance remains the major barrier to effective ovarian cancer treatment. The molecular features and associated biological functions of this phenotype remain poorly understood. We developed carboplatin-resistant cell line models using OVCAR5 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dba976caa985acbed8d2133c8bf88478
Autor:
Georgia Arentz, Mitchell Acland, Martin K. Oehler, Peter Hoffmann, Fergus Whitehead, Manuela Klingler-Hoffmann, Max Mussared
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 10 (2020)
Frontiers in Oncology, Vol 10 (2020)
Serous endometrial cancer (SEC) and high grade serous ovarian cancer (HGSOC) are aggressive gynecological malignancies with high rates of metastasis and poor prognosis. Endometrial intraepithelial carcinoma (EIC), the precursor for SEC, and serous tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad919fdff8702fd10570f92b55662f8
https://doi.org/10.3389/fonc.2020.523989
https://doi.org/10.3389/fonc.2020.523989
Autor:
Leigh Donnellan, Clifford Young, Bradley S. Simpson, Mitchell Acland, Varinderpal S. Dhillon, Maurizio Costabile, Michael Fenech, Peter Hoffmann, Permal Deo
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 7; Pages: 3689
Methylglyoxal (MGO) is a highly reactive cellular metabolite that glycates lysine and arginine residues to form post-translational modifications known as advanced glycation end products. Because of their low abundance and low stoichiometry, few studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91aeca54c471f49a89d70e4b04655459
https://doi.org/10.3390/ijms23073689
https://doi.org/10.3390/ijms23073689
Autor:
Noor A. Lokman, Parul Mittal, Mitchell Acland, Martin K. Oehler, Peter Hoffmann, Manuela Klingler-Hoffmann
Publikováno v:
Proteomics. Clinical applications. 12(3)
Multicellular tumor spheroids (MCTS) are a powerful biological in vitro model, which closely mimics the 3D structure of primary avascularized tumors. Mass spectrometry (MS) has established itself as a powerful analytical tool, not only to better unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbf81f41380ee23c4ef94ced543b7143
https://pubmed.ncbi.nlm.nih.gov/29227035
https://pubmed.ncbi.nlm.nih.gov/29227035