Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Mitchell A Watsky"'
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301495 (2024)
The purpose of this study was to examine transient plasma membrane disruptions (TPMDs) and TPMD-induced Ca++ waves (TPMD Ca++ Wvs) in human and mouse corneal epithelium (HCEC and MCEC). A multi-photon microscope was used to create laser-induced TPMDs
Externí odkaz:
https://doaj.org/article/df067f893fd34cd5a2ffb6c0c0de9413
Publikováno v:
Biomolecules, Vol 13, Iss 12, p 1754 (2023)
Corneal nerve homeostasis is essential for the functional integrity of the ocular surface. Vitamin D deficiency (VDD) and vitamin D receptor knockout (VDR KO) have been found to reduce corneal nerve density in diabetic mice. This is the first study t
Externí odkaz:
https://doaj.org/article/021c25ff439e455c8ce889aef65cf41e
Autor:
Debin Wan, Jun Yang, Bogdan Barnych, Sung Hee Hwang, Kin Sing Stephen Lee, Yongliang Cui, Jun Niu, Mitchell A. Watsky, Bruce D. Hammock
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 4, Pp 798-808 (2017)
There is an increased demand for comprehensive analysis of vitamin D metabolites. This is a major challenge, especially for 1α,25-dihydroxyvitamin D [1α,25(OH)2VitD], because it is biologically active at picomolar concentrations. 4-Phenyl-1,2,4-tri
Externí odkaz:
https://doaj.org/article/0ad7260552ce42c5a1678ae75ca5d0c6
Publikováno v:
International journal of molecular sciences. 23(23)
Corneal wounds resulting from injury, surgeries, or other intrusions not only cause pain, but also can predispose an individual to infection. While some inflammation may be beneficial to protect against microbial infection of wounds, the inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1abb537968e3ddd6c26e2e1bd29ff154
https://pubmed.ncbi.nlm.nih.gov/36499260
https://pubmed.ncbi.nlm.nih.gov/36499260
Publikováno v:
Current Eye Research. 46:1271-1282
Purpose: To investigate the effects of 1,25-Vit D3 and 24,25-Vit D3 on corneal fibroblast expression of the vitamin D-associated enzymes CYP27B1 and CYP24A1 and the roles of the vitamin D receptor (VDR) and protein disulfide isomerase, family A, memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8cbcfe6dbf539ebfd7f9ccdf1d67ddf
https://doi.org/10.1080/02713683.2021.1884726
https://doi.org/10.1080/02713683.2021.1884726
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
The purpose of this study was to determine if transient cell membrane disruptions (TPMDs) in single keratocytes can trigger signaling events in neighboring keratocytes. Stromal cells were cultured from human corneas (HCSC) and mouse corneas (MCSC). T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8db1b3977955171c2c2fc43041fae4e6
http://link.springer.com/article/10.1038/s41598-020-59570-7
http://link.springer.com/article/10.1038/s41598-020-59570-7
Autor:
Teresa E. Fowler, Vivek Choudhary, Samuel Melnyk, Mishma Farsi, Luke Y. Chang, Nyemkuna Fortingo, Xunsheng Chen, Mitchell A. Watsky, Wendy B. Bollag
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 6; Pages: 5839
Our previous work shows that dioleoylphosphatidylglycerol (DOPG) accelerates corneal epithelial healing in vitro and in vivo by unknown mechanisms. Prior data demonstrate that DOPG inhibits toll-like receptor (TLR) activation and inflammation induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d46f7157c74c91a34f375da72ee7f82f
https://doi.org/10.3390/ijms24065839
https://doi.org/10.3390/ijms24065839
Publikováno v:
International Journal of Medical Sciences, Vol 6, Iss 4, Pp 168-176 (2009)
Systemic sclerosis (SSc) is an often fatal disease characterized by autoimmunity and inflammation, leading to widespread vasculopathy and fibrosis. Lysophosphatidic acid (LPA), a bioactive phospholipid in serum, is generated from lysophospholipids se
Externí odkaz:
https://doaj.org/article/2bd7f85742894a49a705bc0143d7c432
Autor:
Laura D. Carbone, Jean Wactawski-Wende, Zhao Chen, Fridtjof Thomas, Joseph C. Larson, Mitchell A. Watsky, Karen C. Johnson, Kathryn E. Bollinger
Publikováno v:
Journal of investigative medicine : the official publication of the American Federation for Clinical Research.
The relationship between vitamin D and glaucoma is controversial. The objective of this study was to examine women from the Women's Health Initiative (WHI) to determine if there is an association between vitamin D and incident glaucoma in postmenopau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::479bf7f9b7cb6262245424556aa39284
https://pubmed.ncbi.nlm.nih.gov/34824141
https://pubmed.ncbi.nlm.nih.gov/34824141
Autor:
Mitchell A. Watsky, Lawrence O. Olala, Rachana Patel, Xiaowen Lu, Amy Estes, David Bogorad, Wendy B. Bollag, Ding Xie, Vivek Choudhary, Haixia Qin
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose In contact with the external environment, the cornea can easily be injured. Although corneal wounds generally heal rapidly, the pain and increased risk of infection associated with a damaged cornea, as well as the impaired healing observed in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94628a1195197083ff100beed70a4c98
http://europepmc.org/articles/PMC7401755
http://europepmc.org/articles/PMC7401755