Zobrazeno 1 - 10 of 111 pro vyhledávání: '"Mitchell A Olman"'
1
Akademický článek
Adenosine 2A receptor antagonist prevented and reversed liver fibrosis in a mouse model of ethanol-exacerbated liver fibrosis.
Autor: Dian J Chiang, Sanjoy Roychowdhury, Katelyn Bush, Megan R McMullen, Sorana Pisano, Kathryn Niese, Mitchell A Olman, Michele T Pritchard, Laura E Nagy
Publikováno v: PLoS ONE, Vol 8, Iss 7, p e69114 (2013)
The effect of moderate alcohol consumption on liver fibrosis is not well understood, but evidence suggests that adenosine may play a role in mediating the effects of moderate ethanol on tissue injury. Ethanol increases the concentration of adenosine
Externí odkaz: https://doaj.org/article/c3c2ecb411044df79aa02fc5ad33cb1e
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2
Akademický článek
Downregulation of FIP200 induces apoptosis of glioblastoma cells and microvascular endothelial cells by enhancing Pyk2 activity.
Autor: Dongyan Wang, Mitchell A Olman, Jerry Stewart, Russell Tipps, Ping Huang, Paul W Sanders, Eric Toline, Richard A Prayson, Jeongwu Lee, Robert J Weil, Cheryl A Palmer, G Yancey Gillespie, Wei Michael Liu, Russell O Pieper, Jun-Lin Guan, Candece L Gladson
Publikováno v: PLoS ONE, Vol 6, Iss 5, p e19629 (2011)
The expression of focal adhesion kinase family interacting protein of 200-kDa (FIP200) in normal brain is limited to some neurons and glial cells. On immunohistochemical analysis of biopsies of glioblastoma tumors, we detected FIP200 in the tumor cel
Externí odkaz: https://doaj.org/article/d91c451f7358437d879aadfc1159132e
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3
Akademický článek
The Role of TRPV4 in Regulating Innate Immune Cell Function in Lung Inflammation
Autor: Rachel G. Scheraga, Brian D. Southern, Lisa M. Grove, Mitchell A. Olman
Publikováno v: Frontiers in Immunology, Vol 11 (2020)
Ion channels/pumps are essential regulators of innate immune cell function. Macrophages have been increasingly recognized to have phenotypic plasticity and location-specific functions in the lung. Transient receptor potential vanilloid 4 (TRPV4) func
Externí odkaz: https://doaj.org/article/cb7d723d6a1b4fb48ff7c46c948b2b17
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4
Akademický článek
The Role of Transient Receptor Potential Vanilloid 4 in Pulmonary Inflammatory Diseases
Autor: Rachel G. Scheraga, Brian D. Southern, Lisa M. Grove, Mitchell A. Olman
Publikováno v: Frontiers in Immunology, Vol 8 (2017)
Ion channels/pumps are essential regulators of organ homeostasis and disease. In the present review, we discuss the role of the mechanosensitive cation channel, transient receptor potential vanilloid 4 (TRPV4), in cytokine secretion and pulmonary inf
Externí odkaz: https://doaj.org/article/e52310729ab24ab6930c91773d9f2452
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6
RSV infection potentiates TRPV1-mediated calcium transport in bronchial epithelium of asthmatic children
Autor: Mitchell A. Olman, Lisa M. Grove, Terri J. Harford, Giovanni Piedimonte, Rachel G. Scheraga, Fariba Rezaee
Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology. 320:L1074-L1084
The transient receptor potential vanilloid 1 (TRPV1) channel is expressed in human bronchial epithelium (HBE), where it transduces Ca2+ in response to airborne irritants. TRPV1 activation results in bronchoconstriction, cough, and mucus production, a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::be47439dc8b8163b4416d0e482f8bd1e
https://doi.org/10.1152/ajplung.00531.2020
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8
Stretching the Function of Innate Immune Cells
Autor: Lisa M. Grove, Rachel G. Scheraga, Brian D. Southern, Apostolos Perelas, Erica M. Orsini, Mitchell A. Olman
Publikováno v: Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
The importance of innate immune cells to sense and respond to their physical environment is becoming increasingly recognized. Innate immune cells (e.g. macrophages and neutrophils) are able to receive mechanical signals through several mechanisms. In
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6faea7d227255ba785f9c0f7bed04e0
https://doi.org/10.3389/fimmu.2021.767319
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