Zobrazeno 1 - 10
of 3 905
pro vyhledávání: '"Mitchel J"'
Microvascular disease is a contributor to persistent pulmonary hypertension in those with chronic thromboembolic pulmonary hypertension (CTEPH). The heterogenous nature of the micro and macrovascular defects motivates the use of personalized computat
Externí odkaz:
http://arxiv.org/abs/2406.01599
Computational hemodynamics models are becoming increasingly useful in the management and prognosis of complex, multiscale pathologies, including those attributed to the development of pulmonary vascular disease. However, diseases like pulmonary hyper
Externí odkaz:
http://arxiv.org/abs/2309.04057
Autor:
Tien T. Sword, Jaime Lorenzo N. Dinglasan, Ghaeath S. K. Abbas, J. William Barker, Madeline E. Spradley, Elijah R. Greene, Damian S. Gooden, Scott J. Emrich, Michael A. Gilchrist, Mitchel J. Doktycz, Constance B. Bailey
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Some of the most metabolically diverse species of bacteria (e.g., Actinobacteria) have higher GC content in their DNA, differ substantially in codon usage, and have distinct protein folding environments compared to tractable expression hosts
Externí odkaz:
https://doaj.org/article/9191929e498f4c4b8578b4821406061b
Autor:
Taylor-LaPole, Alyssa M., Colebank, Mitchel J., Weigand, Justin D., Olufsen, Mette S., Puelz, Charles
Patients with hypoplastic left heart syndrome (HLHS) are born with an underdeveloped left heart. They typically receive a sequence of surgeries that result in a single ventricle physiology called the Fontan circulation. While these patients usually s
Externí odkaz:
http://arxiv.org/abs/2205.10206
Autor:
Paun, L. Mihaela, Colebank, Mitchel J., Taylor-LaPole, Alyssa, Olufsen, Mette S., Ryan, William, Murray, Iain, Salter, James M., Applebaum, Victor, Dunne, Michael, Hollins, Jake, Kimpton, Louise, Volodina, Victoria, Xiong, Xiaoyu, Husmeier, Dirk
Publikováno v:
In Computer Methods in Applied Mechanics and Engineering 1 October 2024 430
Autor:
Jia Wang, Manasa R. Appidi, Leah H. Burdick, Paul E. Abraham, Robert L. Hettich, Dale A. Pelletier, Mitchel J. Doktycz
Publikováno v:
mSystems, Vol 9, Iss 4 (2024)
ABSTRACTUnderstanding the organizational principles of microbial communities is essential for interpreting ecosystem stability. Previous studies have investigated the formation of bacterial communities under nutrient-poor conditions or obligate relat
Externí odkaz:
https://doaj.org/article/e92af6b69aa04ace939b009e24ab510c
Autor:
Carmen A. Moes, C. Tji Gan, Leonie H. Venema, Roland F. Hoffmann, Barbro N. Melgert, Huib A. M. Kerstjens, Peter Olinga, Mitchel J. R. Ruigrok
Publikováno v:
Transplantology, Vol 4, Iss 4, Pp 185-196 (2023)
Background: Donor lungs are often discarded, with gastric aspiration accounting for ~9% of lungs unsuitable for transplantation. To increase the donor pool, it is important to understand the pathophysiology of aspiration-induced lung damage (AILD) an
Externí odkaz:
https://doaj.org/article/701914ac0e3b4994bb04ea75d7718910
Autor:
Bartolo, Michelle A., Qureshi, M. Umar, Colebank, Mitchel J., Chesler, Naomi C., Olufsen, Mette S.
Isolated post-capillary pulmonary hypertension (Ipc-PH) occurs due to left heart failure, which contributes to 1 out of every 9 deaths in the United States. In some patients, through unknown mechanisms, Ipc-PH transitions to combined pre-/post-capill
Externí odkaz:
http://arxiv.org/abs/2103.05754
Autor:
Colebank, Mitchel J., Qureshi, M. Umar, Rajagopal, Sudarshan, Krasuski, Richard A., Olufsen, Mette S.
Chronic thromboembolic pulmonary hypertension (CTEPH) is caused by recurrent or unresolved pulmonary thromboemboli, leading to perfusion defects and increased arterial wave reflections. CTEPH treatment aims to reduce pulmonary arterial pressure and r
Externí odkaz:
http://arxiv.org/abs/2102.06676