Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mitan R. Gokulgandhi"'
Publikováno v:
AAPS PharmSciTech. 15:1238-1251
Development and characterization of dexamethasone (DEX)-encapsulated polymeric nanomicelles have been reported. A low molecular weight di-block copolymer was synthesized and characterized for its structure, molecular weights, critical micelle concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb5eef4e3858cb8ceebbf5685b5d276f
https://doi.org/10.1208/s12249-014-0100-4
https://doi.org/10.1208/s12249-014-0100-4
Publikováno v:
Experimental Eye Research. 118:61-71
Retinoblastoma (RB) is a common malignant intraocular tumor primarily affecting children. Multidrug resistance (MDR) proteins (P-gp and MRPs) mediated chemoresistance have been considered as a major cause of treatment failure in treatment of RB. Ocul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b8b7b433a8893a10638b9f0db000b1
https://doi.org/10.1016/j.exer.2013.10.009
https://doi.org/10.1016/j.exer.2013.10.009
Publikováno v:
Journal of Pharmacy and Pharmacology. 66:574-583
Objectives This work was aim to determine in vitro interaction of moxifloxacin with monocarboxylate transporter (MCT) using a human retinal pigment epithelium cells (ARPE-19). Methods In vitro moxifloxacin uptakes were performed at 37°C across ARPE-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8dea5edf38c444ef61d00d3f9fd7acc
https://doi.org/10.1111/jphp.12139
https://doi.org/10.1111/jphp.12139
Autor:
Mitan R. Gokulgandhi, Pranjali Dalvi, Tanvi Kohli, Mitesh Patel, Susamita Kesh, Dhananjay Pal, Ashim K. Mitra
Publikováno v:
International Journal of Pharmaceutics. 443:245-253
The primary objective of this study is to functionally characterize and provide molecular evidence of large neutral amino acid transporter (LAT1) in human derived prostate cancer cells (PC-3). We carried out the uptake of [3H]-tyrosine to assess the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412edea87610f2511f45d1290d2f14d2
https://doi.org/10.1016/j.ijpharm.2012.12.029
https://doi.org/10.1016/j.ijpharm.2012.12.029
Publikováno v:
Experimental Eye Research. 106:47-54
This study was designed to investigate functional localization of both efflux (P-glycoprotein, P-gp) and influx (peptide) transporters in the mitochondrial membrane of cultured rabbit primary corneal epithelial cells (rPCECs). Isolation and purificat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ec4cdb52c386d463fca077b3e4caa36
https://doi.org/10.1016/j.exer.2012.10.006
https://doi.org/10.1016/j.exer.2012.10.006
Publikováno v:
Expert Opinion on Drug Metabolism & Toxicology. 8:1277-1291
The eye is considered as the most privileged organ because of the blood-ocular barrier that acts as a barrier to systemically administered xenobiotics. However, there has been a significant increase in the number of reports on systemic drug-induced o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4fb180573181d0266ee8d8c2a465b1e
https://doi.org/10.1517/17425255.2012.708337
https://doi.org/10.1517/17425255.2012.708337
Publikováno v:
Medicinal Chemistry. 8:753-768
Poor bioavailability of topically instilled drug is the major concern in the field of ocular drug delivery. Efflux transporters, static and dynamic ocular barriers often possess rate limiting factors for ocular drug therapy. Different formulation str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91d72a0eb490b89452c4dadcbe94783
https://doi.org/10.2174/157340612801216283
https://doi.org/10.2174/157340612801216283
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 27:553-559
Multidrug resistance (MDR) represents a major obstacle to the success of antimicrobial fluoroquinolone (FQ) therapy. MDR-associated efflux protein pumps antimicrobial agents out of the corneal cells, leading to suboptimal eradication of microbes. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9affa7ed9bb718be519deefef91f7d56
https://doi.org/10.1089/jop.2011.0076
https://doi.org/10.1089/jop.2011.0076
Autor:
Mohammad A. Khanfar, Khalid A. El Sayed, Anbalagan Muralidharan, Mitan R. Gokulgandhi, Girish V. Shah, Shibu Thomas, Mudit Mudit
Publikováno v:
Molecular Cancer Therapeutics. 8:509-520
Expression of calcitonin (CT) and its receptor (CTR) is elevated in advanced prostate cancer, and activated CT-CTR autocrine axis plays a pivotal role in tumorigenicity and metastatic potential of multiple prostate cancer cell lines. Recent studies s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee4ae2bdb2227a48a95ec185a948cb7
https://doi.org/10.1158/1535-7163.mct-08-0693
https://doi.org/10.1158/1535-7163.mct-08-0693
Publikováno v:
International journal of pharmaceutics. 489(1-2)
Acylation of peptide has been reported for a number of peptides and proteins during release from polymers comprising of lactide and glycolide. We hypothesize that reversible hydrophobic ion-pairing (HIP) complex may minimize octreotide acylation duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7515841bdf31a76dfb6e424b478bd94f
https://pubmed.ncbi.nlm.nih.gov/25940041
https://pubmed.ncbi.nlm.nih.gov/25940041