Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mital Vasoya"'
Autor:
Venugopalan D. Nair, Hanna Pincas, Mary Anne S. Amper, Yongchao Ge, Mital Vasoya, Archana Natarajan Raja, Martin J. Walsh, Stuart C. Sealfon
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 103007- (2024)
Summary: Although reduced representation bisulfite sequencing (RRBS) measures DNA methylation (DNAme) across CpG-rich genomic regions with high sensitivity, the assay can be time-consuming and prone to batch effects. Here, we present a high-throughpu
Externí odkaz:
https://doaj.org/article/590d1fb6a61b40cd954ed0779e8c2e75
Autor:
Weiguang Mao, Clare M Miller, Venugopalan D Nair, Yongchao Ge, Mary Anne S Amper, Antonio Cappuccio, Mary‐Catherine George, Carl W Goforth, Kristy Guevara, Nada Marjanovic, German Nudelman, Hanna Pincas, Irene Ramos, Rachel S G Sealfon, Alessandra Soares‐Schanoski, Sindhu Vangeti, Mital Vasoya, Dawn L Weir, Elena Zaslavsky, Biobank Team, Vanessa Barcessat, Kevin Tuballes, Diane Marie Del Valle, Kai Nie, Hui Xie, Grace Chung, Manishkumar Patel, Jocelyn Harris, Kimberly Argueta, Jacques Fehr, Barr Gruberg, Nicholas Zaki, Seunghee Kim‐Schulze, Sacha Gnjatic, Miriam Merad, Andrew G Letizia, Olga G Troyanskaya, Stuart C Sealfon, Maria Chikina
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 5, Pp 1-16 (2023)
Abstract DNA methylation comprises a cumulative record of lifetime exposures superimposed on genetically determined markers. Little is known about methylation dynamics in humans following an acute perturbation, such as infection. We characterized the
Externí odkaz:
https://doaj.org/article/4218baf29182454bb07788f37ce0f8e4
Autor:
Zidong Zhang, Michel Zamojski, Gregory R. Smith, Thea L. Willis, Val Yianni, Natalia Mendelev, Hanna Pincas, Nitish Seenarine, Mary Anne S. Amper, Mital Vasoya, Wan Sze Cheng, Elena Zaslavsky, Venugopalan D. Nair, Judith L. Turgeon, Daniel J. Bernard, Olga G. Troyanskaya, Cynthia L. Andoniadou, Stuart C. Sealfon, Frederique Ruf-Zamojski
Publikováno v:
Cell Reports, Vol 38, Iss 10, Pp 110467- (2022)
Summary: Despite their importance in tissue homeostasis and renewal, human pituitary stem cells (PSCs) are incompletely characterized. We describe a human single nucleus RNA-seq and ATAC-seq resource from pediatric, adult, and aged postmortem pituita
Externí odkaz:
https://doaj.org/article/9778f6fbae6c4b3ebc1fa18a2a9f30e3
Autor:
Venugopalan D. Nair, Mital Vasoya, Vishnu Nair, Gregory R. Smith, Hanna Pincas, Yongchao Ge, Collin M. Douglas, Karyn A. Esser, Stuart C. Sealfon
Publikováno v:
MethodsX, Vol 9, Iss , Pp 101681- (2022)
ATAC-seq is a fast and sensitive method for the epigenomic profiling of open chromatin and for mapping of transcription factor binding sites [1]. Despite the development of the Omni-ATAC protocol for the profiling of chromatin accessibility in frozen
Externí odkaz:
https://doaj.org/article/230c6c9f8a2a426ba34088c697d8b42b
Autor:
Natalie Sauerwald, Zijun Zhang, Irene Ramos, Venugopalan D. Nair, Alessandra Soares-Schanoski, Yongchao Ge, Weiguang Mao, Hala Alshammary, Ana S. Gonzalez-Reiche, Adriana van de Guchte, Carl W. Goforth, Rhonda A. Lizewski, Stephen E. Lizewski, Mary Anne S. Amper, Mital Vasoya, Nitish Seenarine, Kristy Guevara, Nada Marjanovic, Clare M. Miller, German Nudelman, Megan A. Schilling, Rachel S.G. Sealfon, Michael S. Termini, Sindhu Vangeti, Dawn L. Weir, Elena Zaslavsky, Maria Chikina, Ying Nian Wu, Harm Van Bakel, Andrew G. Letizia, Stuart C. Sealfon, Olga G. Troyanskaya
Publikováno v:
Cell systems. 13(11)
Male sex is a major risk factor for SARS-CoV-2 infection severity. To understand the basis for this sex difference, we studied SARS-CoV-2 infection in a young adult cohort of United States Marine recruits. Among 2,641 male and 244 female unvaccinated
Autor:
Venugopalan D. Nair, Mital Vasoya, Vishnu Nair, Gregory R. Smith, Hanna Pincas, Yongchao Ge, Collin M. Douglas, Karyn A. Esser, Stuart C. Sealfon
Publikováno v:
MethodsX. 9
ATAC-seq is a fast and sensitive method for the epigenomic profiling of open chromatin and for mapping of transcription factor binding sites [1]. Despite the development of the Omni-ATAC protocol for the profiling of chromatin accessibility in frozen
Autor:
Yianni, Zinan Zhang, Thea L. Willis, Daniel J. Bernard, Nitish Seenarine, Amper Mas, Frederique Ruf-Zamojski, Mital Vasoya, Venugopalan D. Nair, Cynthia L. Andoniadou, Olga G. Troyanskaya, Michel Zamojski, Turgeon Jl, Gregory R. Smith, Stuart C. Sealfon, Hanna Pincas, Natalia Mendelev
Despite their importance in tissue homeostasis and renewal, human pituitary stem cells (PSCs) are incompletely characterized. We describe a human single nucleus (sn) RNAseq and ATACseq resource from pediatric, adult, and aged pituitaries (snpituitary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5df03c3de7bc89902f87d72b5539cefe
https://doi.org/10.1101/2021.06.18.449034
https://doi.org/10.1101/2021.06.18.449034
Autor:
Vishnu Nair, Mital Vasoya, Karyn A. Esser, Stuart C. Sealfon, Yongchao Ge, Gregory R. Smith, Venugopalan D. Nair, Collin M Douglas, Hanna Pincas
Publikováno v:
Genomics. 113(6)
Chromatin accessibility is a key factor influencing gene expression. We optimized the Omni-ATAC-seq protocol and used it together with RNA-seq to investigate cis-regulatory elements in rat white adipose and skeletal muscle, two tissues with contrasti
Autor:
Nitish Seenarine, Mital Vasoya, Hanna Pincas, Frederique Ruf-Zamojski, Stuart C. Sealfon, Gauthier Schang, Zidong Zhang, Corrine K. Welt, Luisina Ongaro Gambino, Mary Anne S. Amper, Judith L Turgeon, Venugopalan D. Nair, Olga G. Troyanskaya, Cynthia L. Andoniadou, Michel Zamojski, Natalia Mendelev, Gregory R. Smith, Daniel J. Bernard, Thea L. Willis, Val Yianni, Sagie Mofsowitz, Xiang Zhou
Publikováno v:
Journal of the Endocrine Society
The pituitary gland regulates key physiological functions, including growth, sexual maturation, reproduction, and lactation. Here, we present a paired single-nuclei (sn) transcriptome and chromatin accessibility characterization of six post-mortem hu