Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Misty R. Jenkins"'
Autor:
Brittany Dewdney, Misty R. Jenkins, Sarah A. Best, Saskia Freytag, Krishneel Prasad, Jeff Holst, Raelene Endersby, Terrance G. Johns
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-33 (2023)
Abstract Glioblastoma, a rare, and highly lethal form of brain cancer, poses significant challenges in terms of therapeutic resistance, and poor survival rates for both adult and paediatric patients alike. Despite advancements in brain cancer researc
Externí odkaz:
https://doaj.org/article/25a76f42a553482c83f4cd6bc8c701e4
Autor:
Stacie S. Wang, Kirti Pandey, Katherine A. Watson, Rebecca C. Abbott, Nicole A. Mifsud, Fiona M. Gracey, Sri H. Ramarathinam, Ryan S. Cross, Anthony W. Purcell, Misty R. Jenkins
Publikováno v:
Molecular Therapy: Oncolytics, Vol 30, Iss , Pp 167-180 (2023)
Diffuse midline glioma (DMG) is a childhood brain tumor with an extremely poor prognosis. Chimeric antigen receptor (CAR) T cell therapy has recently demonstrated some success in DMG, but there may a need to target multiple tumor-specific targets to
Externí odkaz:
https://doaj.org/article/aea552a56a254441a4a3a7761c91f3b0
Publikováno v:
Molecular Oncology, Vol 17, Iss 6, Pp 946-949 (2023)
Synthetic biology has made it possible to rewire natural cellular responses to treat disease, notably demonstrated by chimeric antigen receptor (CAR) T cells as cancer immunotherapy. Building on the success of T‐cell activation using synthetic rece
Externí odkaz:
https://doaj.org/article/ccc31952cdbc4b9bb5494cb6648da9f3
Autor:
Kirti Pandey, Stacie S. Wang, Nicole A. Mifsud, Pouya Faridi, Alexander J. Davenport, Andrew I. Webb, Jarrod J. Sandow, Rochelle Ayala, Michelle Monje, Ryan S. Cross, Sri H. Ramarathinam, Misty R. Jenkins, Anthony W. Purcell
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionDiffuse intrinsic pontine glioma (DIPG), recently reclassified as a subtype of diffuse midline glioma, is a highly aggressive brainstem tumor affecting children and young adults, with no cure and a median survival of only 9 months. Conven
Externí odkaz:
https://doaj.org/article/cca9faeeedb64a64829693d53680c424
Autor:
Kelden Richardson, Simon P. Keam, Joe Jiang Zhu, Deborah Meyran, Criselle D’Souza, Sean Macdonald, Kerry Campbell, Michael Robbins, Natalie A. Bezman, Kirsten Todd, Hang Quach, David S. Ritchie, Simon J. Harrison, H. Miles Prince, Joseph A. Trapani, Misty R. Jenkins, Paul A. Beavis, Phillip K. Darcy, Paul J. Neeson
Publikováno v:
Haematologica, Vol 108, Iss 1 (2022)
Patients with refractory relapsed multiple myeloma respond to combination treatment with elotuzumab and lenalidomide. The mechanisms underlying this observation are not fully understood. Furthermore, biomarkers predictive of response have not been id
Externí odkaz:
https://doaj.org/article/330bde42af204d128415d365b42720c4
Autor:
Natalie A. Bezman, Amy Jhatakia, Alper Y. Kearney, Ty Brender, Mark Maurer, Karla Henning, Misty R. Jenkins, Amy J. Rogers, Paul J. Neeson, Alan J. Korman, Michael D. Robbins, Robert F. Graziano
Publikováno v:
Blood Advances, Vol 1, Iss 12, Pp 753-765 (2017)
Abstract: Elotuzumab, a humanized monoclonal antibody that binds human signaling lymphocytic activation molecule F7 (hSLAMF7) on myeloma cells, was developed to treat patients with multiple myeloma (MM). Elotuzumab has a dual mechanism of action that
Externí odkaz:
https://doaj.org/article/b48d5441929d44dabeefb1b6238bb93b
Autor:
Assaf Elazar, Nicholas J Chandler, Ashleigh S Davey, Jonathan Y Weinstein, Julie V Nguyen, Raphael Trenker, Ryan S Cross, Misty R Jenkins, Melissa J Call, Matthew E Call, Sarel J Fleishman
Publikováno v:
eLife, Vol 11 (2022)
De novo-designed receptor transmembrane domains (TMDs) present opportunities for precise control of cellular receptor functions. We developed a de novo design strategy for generating programmed membrane proteins (proMPs): single-pass α-helical TMDs
Externí odkaz:
https://doaj.org/article/4c88ae4a5ecb43b5a0ea6b73ec898c18
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 4 (2022)
Externí odkaz:
https://doaj.org/article/068a27091a32436b81384e8be1359799
Autor:
Rebecca C Abbott, Daniel J Verdon, Fiona M Gracey, Hannah E Hughes‐Parry, Melinda Iliopoulos, Katherine A Watson, Matthias Mulazzani, Kylie Luong, Colleen D’Arcy, Lucy C Sullivan, Ben R Kiefel, Ryan S Cross, Misty R Jenkins
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 5, Pp n/a-n/a (2021)
Abstract Objectives The increasing success of Chimeric Antigen Receptor (CAR) T cell therapy in haematological malignancies is reinvigorating its application in many other cancer types and with renewed focus on its application to solid tumors. We pre
Externí odkaz:
https://doaj.org/article/bf76bd27261b474fb7938f17c07c871c
Autor:
Sneha Sant, Misty R Jenkins, Pradyot Dash, Katherine A Watson, Zhongfang Wang, Angela Pizzolla, Marios Koutsakos, Thi HO Nguyen, Martha Lappas, Jane Crowe, Tom Loudovaris, Stuart I Mannering, Glen P Westall, Tom C Kotsimbos, Allen C Cheng, Linda Wakim, Peter C Doherty, Paul G Thomas, Liyen Loh, Katherine Kedzierska
Publikováno v:
Clinical & Translational Immunology, Vol 8, Iss 9, Pp n/a-n/a (2019)
Abstract Background Although γδ T cells comprise up to 10% of human peripheral blood T cells, questions remain regarding their role in disease states and T‐cell receptor (TCR) clonal expansions. We dissected anti‐viral functions of human γδ T
Externí odkaz:
https://doaj.org/article/7ff1b72faa64454082fb640c16d1ffe8