Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Misty R Jenkins"'
Autor:
Katharine J Drummond, Jordan R Hansford, Misty R Jenkins, Lisa M Ebert, Leesa Lertsumitkul, Melinda Iliopoulos, Stacie S Wang, Sarah J McArthur, Alexander J Davenport, Raelene Endersby, Ryan Cross
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 8 (2024)
Background High-grade gliomas including glioblastoma (GBM) and diffuse midline gliomas (DMG) represent the most lethal and aggressive brain cancers where current treatment modalities offer limited efficacy. Chimeric antigen receptor (CAR) T cell ther
Externí odkaz:
https://doaj.org/article/ddf80a4505ed43e2bee311a611917b42
Autor:
Rebecca C Abbott, Melinda Iliopoulos, Katherine A Watson, Valeria Arcucci, Margareta Go, Hannah E Hughes‐Parry, Pete Smith, Melissa J Call, Ryan S Cross, Misty R Jenkins
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 3, Pp n/a-n/a (2023)
Abstract Objectives Glioblastoma is a highly aggressive and fatal brain malignancy, and effective targeted therapies are required. The combination of standard treatments including surgery, chemotherapy and radiotherapy is not curative. Chimeric antig
Externí odkaz:
https://doaj.org/article/daa67b3f5e504aa1970ae6379d7e3fcb
Autor:
Assaf Elazar, Nicholas J Chandler, Ashleigh S Davey, Jonathan Y Weinstein, Julie V Nguyen, Raphael Trenker, Ryan S Cross, Misty R Jenkins, Melissa J Call, Matthew E Call, Sarel J Fleishman
Publikováno v:
eLife, Vol 11 (2022)
De novo-designed receptor transmembrane domains (TMDs) present opportunities for precise control of cellular receptor functions. We developed a de novo design strategy for generating programmed membrane proteins (proMPs): single-pass α-helical TMDs
Externí odkaz:
https://doaj.org/article/4c88ae4a5ecb43b5a0ea6b73ec898c18
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 4 (2022)
Externí odkaz:
https://doaj.org/article/068a27091a32436b81384e8be1359799
Autor:
Rebecca C Abbott, Daniel J Verdon, Fiona M Gracey, Hannah E Hughes‐Parry, Melinda Iliopoulos, Katherine A Watson, Matthias Mulazzani, Kylie Luong, Colleen D’Arcy, Lucy C Sullivan, Ben R Kiefel, Ryan S Cross, Misty R Jenkins
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 5, Pp n/a-n/a (2021)
Abstract Objectives The increasing success of Chimeric Antigen Receptor (CAR) T cell therapy in haematological malignancies is reinvigorating its application in many other cancer types and with renewed focus on its application to solid tumors. We pre
Externí odkaz:
https://doaj.org/article/bf76bd27261b474fb7938f17c07c871c
Autor:
Sneha Sant, Misty R Jenkins, Pradyot Dash, Katherine A Watson, Zhongfang Wang, Angela Pizzolla, Marios Koutsakos, Thi HO Nguyen, Martha Lappas, Jane Crowe, Tom Loudovaris, Stuart I Mannering, Glen P Westall, Tom C Kotsimbos, Allen C Cheng, Linda Wakim, Peter C Doherty, Paul G Thomas, Liyen Loh, Katherine Kedzierska
Publikováno v:
Clinical & Translational Immunology, Vol 8, Iss 9, Pp n/a-n/a (2019)
Abstract Background Although γδ T cells comprise up to 10% of human peripheral blood T cells, questions remain regarding their role in disease states and T‐cell receptor (TCR) clonal expansions. We dissected anti‐viral functions of human γδ T
Externí odkaz:
https://doaj.org/article/7ff1b72faa64454082fb640c16d1ffe8
Autor:
Misty R Jenkins, Jane C Stinchcombe, Byron B Au-Yeung, Yukako Asano, Alex T Ritter, Arthur Weiss, Gillian M Griffiths
Publikováno v:
eLife, Vol 3 (2014)
T cell receptor (TCR) activation leads to a dramatic reorganisation of both membranes and receptors as the immunological synapse forms. Using a genetic model to rapidly inhibit Zap70 catalytic activity we examined synapse formation between cytotoxic
Externí odkaz:
https://doaj.org/article/e70e5a1f66ad48a2831d41bc26545289
Autor:
Paul J. Neeson, Phillip K. Darcy, Michael H. Kershaw, Joseph A. Trapani, David S. Ritchie, H. Miles Prince, Carmen S. Yong, Ryan S. Cross, Misty R. Jenkins, Alexander J. Davenport
Adoptive therapy with chimeric antigen receptor (CAR) T cells shows great promise clinically. However, there are important aspects of CAR-T-cell biology that have not been explored, particularly with respect to the kinetics of activation, immune syna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae2664785a285bb49ff5f9a4ce793a3b
https://doi.org/10.1158/2326-6066.c.6548806.v1
https://doi.org/10.1158/2326-6066.c.6548806.v1
Autor:
Paul J. Neeson, Phillip K. Darcy, Michael H. Kershaw, Joseph A. Trapani, David S. Ritchie, H. Miles Prince, Carmen S. Yong, Ryan S. Cross, Misty R. Jenkins, Alexander J. Davenport
Movie 5. Serial killing of tumor targets by CAR.OT-I effector cells following engagement through the CAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02736380182beccb475773a65593a9df
https://doi.org/10.1158/2326-6066.22538515
https://doi.org/10.1158/2326-6066.22538515
Autor:
Paul J. Neeson, Phillip K. Darcy, Michael H. Kershaw, Joseph A. Trapani, David S. Ritchie, H. Miles Prince, Carmen S. Yong, Ryan S. Cross, Misty R. Jenkins, Alexander J. Davenport
Movie 2. CAR.OT-I cells co-cultured with MC57-OVA257 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8722c039ce594ac04ed58f03f4a15a52
https://doi.org/10.1158/2326-6066.22538524.v1
https://doi.org/10.1158/2326-6066.22538524.v1