Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Misty R Jenkins"'
Autor:
Katharine J Drummond, Jordan R Hansford, Misty R Jenkins, Lisa M Ebert, Leesa Lertsumitkul, Melinda Iliopoulos, Stacie S Wang, Sarah J McArthur, Alexander J Davenport, Raelene Endersby, Ryan Cross
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 8 (2024)
Background High-grade gliomas including glioblastoma (GBM) and diffuse midline gliomas (DMG) represent the most lethal and aggressive brain cancers where current treatment modalities offer limited efficacy. Chimeric antigen receptor (CAR) T cell ther
Externí odkaz:
https://doaj.org/article/ddf80a4505ed43e2bee311a611917b42
Autor:
Brittany Dewdney, Misty R. Jenkins, Sarah A. Best, Saskia Freytag, Krishneel Prasad, Jeff Holst, Raelene Endersby, Terrance G. Johns
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-33 (2023)
Abstract Glioblastoma, a rare, and highly lethal form of brain cancer, poses significant challenges in terms of therapeutic resistance, and poor survival rates for both adult and paediatric patients alike. Despite advancements in brain cancer researc
Externí odkaz:
https://doaj.org/article/25a76f42a553482c83f4cd6bc8c701e4
Autor:
Stacie S. Wang, Kirti Pandey, Katherine A. Watson, Rebecca C. Abbott, Nicole A. Mifsud, Fiona M. Gracey, Sri H. Ramarathinam, Ryan S. Cross, Anthony W. Purcell, Misty R. Jenkins
Publikováno v:
Molecular Therapy: Oncolytics, Vol 30, Iss , Pp 167-180 (2023)
Diffuse midline glioma (DMG) is a childhood brain tumor with an extremely poor prognosis. Chimeric antigen receptor (CAR) T cell therapy has recently demonstrated some success in DMG, but there may a need to target multiple tumor-specific targets to
Externí odkaz:
https://doaj.org/article/aea552a56a254441a4a3a7761c91f3b0
Publikováno v:
Molecular Oncology, Vol 17, Iss 6, Pp 946-949 (2023)
Synthetic biology has made it possible to rewire natural cellular responses to treat disease, notably demonstrated by chimeric antigen receptor (CAR) T cells as cancer immunotherapy. Building on the success of T‐cell activation using synthetic rece
Externí odkaz:
https://doaj.org/article/ccc31952cdbc4b9bb5494cb6648da9f3
Autor:
Kirti Pandey, Stacie S. Wang, Nicole A. Mifsud, Pouya Faridi, Alexander J. Davenport, Andrew I. Webb, Jarrod J. Sandow, Rochelle Ayala, Michelle Monje, Ryan S. Cross, Sri H. Ramarathinam, Misty R. Jenkins, Anthony W. Purcell
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionDiffuse intrinsic pontine glioma (DIPG), recently reclassified as a subtype of diffuse midline glioma, is a highly aggressive brainstem tumor affecting children and young adults, with no cure and a median survival of only 9 months. Conven
Externí odkaz:
https://doaj.org/article/cca9faeeedb64a64829693d53680c424
Autor:
Rebecca C Abbott, Melinda Iliopoulos, Katherine A Watson, Valeria Arcucci, Margareta Go, Hannah E Hughes‐Parry, Pete Smith, Melissa J Call, Ryan S Cross, Misty R Jenkins
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 3, Pp n/a-n/a (2023)
Abstract Objectives Glioblastoma is a highly aggressive and fatal brain malignancy, and effective targeted therapies are required. The combination of standard treatments including surgery, chemotherapy and radiotherapy is not curative. Chimeric antig
Externí odkaz:
https://doaj.org/article/daa67b3f5e504aa1970ae6379d7e3fcb
Autor:
Kelden Richardson, Simon P. Keam, Joe Jiang Zhu, Deborah Meyran, Criselle D’Souza, Sean Macdonald, Kerry Campbell, Michael Robbins, Natalie A. Bezman, Kirsten Todd, Hang Quach, David S. Ritchie, Simon J. Harrison, H. Miles Prince, Joseph A. Trapani, Misty R. Jenkins, Paul A. Beavis, Phillip K. Darcy, Paul J. Neeson
Publikováno v:
Haematologica, Vol 108, Iss 1 (2022)
Patients with refractory relapsed multiple myeloma respond to combination treatment with elotuzumab and lenalidomide. The mechanisms underlying this observation are not fully understood. Furthermore, biomarkers predictive of response have not been id
Externí odkaz:
https://doaj.org/article/330bde42af204d128415d365b42720c4
Autor:
Assaf Elazar, Nicholas J Chandler, Ashleigh S Davey, Jonathan Y Weinstein, Julie V Nguyen, Raphael Trenker, Ryan S Cross, Misty R Jenkins, Melissa J Call, Matthew E Call, Sarel J Fleishman
Publikováno v:
eLife, Vol 11 (2022)
De novo-designed receptor transmembrane domains (TMDs) present opportunities for precise control of cellular receptor functions. We developed a de novo design strategy for generating programmed membrane proteins (proMPs): single-pass α-helical TMDs
Externí odkaz:
https://doaj.org/article/4c88ae4a5ecb43b5a0ea6b73ec898c18
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 4 (2022)
Externí odkaz:
https://doaj.org/article/068a27091a32436b81384e8be1359799
Autor:
Rebecca C Abbott, Daniel J Verdon, Fiona M Gracey, Hannah E Hughes‐Parry, Melinda Iliopoulos, Katherine A Watson, Matthias Mulazzani, Kylie Luong, Colleen D’Arcy, Lucy C Sullivan, Ben R Kiefel, Ryan S Cross, Misty R Jenkins
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 5, Pp n/a-n/a (2021)
Abstract Objectives The increasing success of Chimeric Antigen Receptor (CAR) T cell therapy in haematological malignancies is reinvigorating its application in many other cancer types and with renewed focus on its application to solid tumors. We pre
Externí odkaz:
https://doaj.org/article/bf76bd27261b474fb7938f17c07c871c