Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Misty Martin"'
Autor:
Mona Hoseini Soflaee, Rushendhiran Kesavan, Umakant Sahu, Alpaslan Tasdogan, Elodie Villa, Zied Djabari, Feng Cai, Diem H. Tran, Hieu S. Vu, Eunus S. Ali, Halie Rion, Brendan P. O’Hara, Sherwin Kelekar, James Hughes Hallett, Misty Martin, Thomas P. Mathews, Peng Gao, John M. Asara, Brendan D. Manning, Issam Ben-Sahra, Gerta Hoxhaj
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Nucleotides are essential for different biological processes and have been also associated to cancer development. Depleting cellular nucleotides is a strategy commonly employed to target cancers. Here, the authors show that purine depletion induces s
Externí odkaz:
https://doaj.org/article/e65828f4fe7b450899c62fcdaa40754f
Autor:
Stacy Y. Kasitinon, Ugur Eskiocak, Misty Martin, Divya Bezwada, Vishal Khivansara, Alpaslan Tasdogan, Zhiyu Zhao, Thomas Mathews, Arin B. Aurora, Sean J. Morrison
Publikováno v:
Cell Reports, Vol 28, Iss 9, Pp 2293-2305.e9 (2019)
Summary: We screen ion channels and transporters throughout the genome to identify those required by human melanoma cells but not by normal human melanocytes. We discover that Mucolipin-1 (MCOLN1), which encodes the lysosomal cation channel TRPML1, i
Externí odkaz:
https://doaj.org/article/167bcf5cf7ce4415b1b79af20d367b01
Autor:
Paula Stigler Granados, Zacariah L. Hildenbrand, Claudia Mata, Sabrina Habib, Misty Martin, Doug Carlton, Inês C. Santos, Kevin A. Schug, Lawrence Fulton
Publikováno v:
Water, Vol 11, Iss 8, p 1633 (2019)
The expansion of unconventional oil and gas development (UD) across the US continues to be at the center of debates regarding safety to health and the environment. This descriptive study evaluated the water quality of private water wells in the Eagle
Externí odkaz:
https://doaj.org/article/f9204b4eede94a0fb74db58ee8b32f79
Autor:
Zheng Wu, Divya Bezwada, Robert C Harris, Chunxiao Pan, Phong T Nguyen, Brandon Faubert, Ling Cai, Feng Cai, Hieu S. Vu, Hongli Chen, Misty Martin- Sandoval, Duyen Do, Wen Gu, Yuannyu Zhang, Bookyung Ko, Bailey Brooks, Sherwin Kelekar, Yuanyuan Zhang, Lauren G Zacharias, K. Celeste Oaxaca, Thomas P Mathews, Javier Garcia-Bermudez, Min Ni, Ralph J. DeBerardinis
Publikováno v:
bioRxiv
SUMMARYCancer cells reprogram their metabolism to support cell growth and proliferation in harsh environments. While many studies have documented the importance of mitochondrial oxidative phosphorylation (OXPHOS) in tumor growth, some cancer cells ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc11f975d120e82f91241623f27adc61
https://europepmc.org/articles/PMC10197673/
https://europepmc.org/articles/PMC10197673/
Autor:
Feng Cai, Divya Bezwada, Ling Cai, Rohit Mahar, Zheng Wu, Panayotis Pachnis, Chendong Yang, Sherwin Kelekar, Wen Gu, Hieu S. Vu, Thomas P. Mathews, Lauren G. Zacharias, Misty Martin-Sandoval, Duyen Do, K. Celeste Oaxaca, Eunsook S. Jin, Vitaly Margulis, Craig R. Malloy, Matthew E. Merritt, Ralph J. DeBerardinis
SUMMARYStable isotopes are powerful tools to assess metabolism.13C labeling is detected using nuclear magnetic resonance spectroscopy (NMRS) or mass spectrometry (MS). MS has excellent sensitivity but generally cannot discriminate among different13C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::830df46c3668a0f6d46f8d2336407eb6
https://doi.org/10.1101/2022.07.31.502208
https://doi.org/10.1101/2022.07.31.502208
Autor:
Arin B. Aurora, Vishal Khivansara, Ashley Leach, Jennifer G. Gill, Misty Martin-Sandoval, Chendong Yang, Stacy Y. Kasitinon, Divya Bezwada, Alpaslan Tasdogan, Wen Gu, Thomas P. Mathews, Zhiyu Zhao, Ralph J. DeBerardinis, Sean J. Morrison
The pentose phosphate pathway is a major source of NADPH for oxidative stress resistance in cancer cells but there is limited insight into its role in metastasis, when some cancer cells experience high levels of oxidative stress. To address this, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449e4171d043e6d88da4db81b47c08f4
https://www.ncbi.nlm.nih.gov/pubmed/35110412
https://www.ncbi.nlm.nih.gov/pubmed/35110412
Autor:
Vijayashree Ramesh, Ashley Solmonson, Zhimin Gu, Stacy Y. Kasitinon, Alpaslan Tasdogan, Jessalyn M. Ubellacker, Dirk Schadendorf, Misty Martin, Malea M. Murphy, Travis Vandergriff, Brandon Faubert, Sean J. Morrison, Wen Gu, Ralph J. DeBerardinis, Zhiyu Zhao, Thomas P. Mathews, Bo Shen
Publikováno v:
Nature
Metastasis requires cancer cells to undergo poorly-understood metabolic changes1–3. We found that metabolic differences among melanoma cells confer differences in metastatic potential as a result of differences in Monocarboxylate Transporter 1 (MCT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b268d24b8c70281e12f752ca2b409a
http://europepmc.org/articles/PMC6930341
http://europepmc.org/articles/PMC6930341
Autor:
Arin B. Aurora, Alpaslan Tasdogan, Ugur Eskiocak, Sean J. Morrison, Thomas P. Mathews, Zhiyu Zhao, Stacy Y. Kasitinon, Misty Martin, Divya Bezwada, Vishal Khivansara
Publikováno v:
Cell Reports, Vol 28, Iss 9, Pp 2293-2305.e9 (2019)
Cell reports
Cell reports
SUMMARY We screen ion channels and transporters throughout the genome to identify those required by human melanoma cells but not by normal human melanocytes. We discover that Mucolipin-1 (MCOLN1), which encodes the lysosomal cation channel TRPML1, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba119388cfb38479d2ef3c052f5eb2cd
http://www.sciencedirect.com/science/article/pii/S2211124719310022
http://www.sciencedirect.com/science/article/pii/S2211124719310022
Autor:
Catherine A. Makarewich, Rhonda Bassel-Duby, John R. McAnally, Svetlana Bezprozvannaya, Thomas P Matthews, Sean J. Morrison, Eric N. Olson, Misty Martin, Amir Z Munir, Aaron M. Gibson
Publikováno v:
Circulation. 142
Introduction: Emerging evidence suggests that many RNA molecules currently annotated as noncoding contain short open reading frames that code for functional small proteins called microproteins. Microproteins play critical roles in a diverse range of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::784e26504eea5d4d989de15afc92aad0
https://doi.org/10.1161/circ.142.suppl_3.16602
https://doi.org/10.1161/circ.142.suppl_3.16602
Autor:
Matthew H. Porteus, Wenqing Wang, Sean J. Morrison, Andrew Devilbiss, Zhiyu Zhao, Daniel P. Dever, Martin Arreola, Avni Awani, Katja G. Weinacht, Misty Martin, Thomas P. Mathews
Publikováno v:
Blood. 136:33-33
Energy deficiency and redox stress are hallmarks of mitochondrial pathology. Reductive stress is marked by an accumulation of reducing species and can arise from defects in the electron transport chain (ETC) that prevent NAD+ regeneration from NADH.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c70295ab712f0dab28cec608097e6ea
https://doi.org/10.1182/blood-2020-138560
https://doi.org/10.1182/blood-2020-138560