Výsledky vyhledávání - "Misty M. Thompson"

Akademický článek

Translocator protein 18 kDa (TSPO) is regulated in white and brown adipose tissue by obesity.

Autor: Misty M Thompson, H Charles Manning, Kate L J Ellacott

Publikováno v: PLoS ONE, Vol 8, Iss 11, p e79980 (2013)

Translocator protein 18 kDa (TSPO) is an outer-mitochondrial membrane transporter which has many functions including participation in the mitochondrial permeability transition pore, regulation of reactive oxygen species (ROS), production of cellular

Externí odkaz: https://doaj.org/article/1d815749d6de40c4a7f304e1eafae6b5

Zobrazit plný text záznamu

Evidence for a novel functional role of astrocytes in the acute homeostatic response to high-fat diet intake in mice

Autor: Misty M. Thompson, Laura B. Buckman, Timothy S. Blackwell, Rachel N. Lippert, Fiona E. Yull, Kate L. J. Ellacott

Publikováno v: Molecular Metabolism

Objective Introduction of a high-fat diet to mice results in a period of voracious feeding, known as hyperphagia, before homeostatic mechanisms prevail to restore energy intake to an isocaloric level. Acute high-fat diet hyperphagia induces astrocyte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4026b60e8bec465099b7de08cd9f43
https://doi.org/10.1016/j.molmet.2014.10.001

Zobrazit plný text záznamu

Obesity induced by a high-fat diet is associated with increased immune cell entry into the central nervous system

Autor: Laura B. Buckman, David K. Flaherty, Christopher T. Buckman, Misty M. Thompson, Alyssa H. Hasty, Kevin P. Weller, Kate L. J. Ellacott, Brittany K. Matlock

Publikováno v: Brain, Behavior, and Immunity. 35:33-42

Obesity is associated with chronic low-grade inflammation in peripheral tissues caused, in part, by the recruitment of inflammatory monocytes into adipose tissue. Studies in rodent models have also shown increased inflammation in the central nervous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b254923777e2c70d1dd043d63c6cca
https://doi.org/10.1016/j.bbi.2013.06.007

Zobrazit plný text záznamu

Paradoxical roles of serine racemase and d-serine in the G93A mSOD1 mouse model of amyotrophic lateral sclerosis

Autor: John C. Marecki, Misty M. Thompson, Steven W. Barger, John C. Roder, John P. Crow, Stéphane Marinesco, Viviane Labrie

Publikováno v: Journal of Neurochemistry. 120:598-610

D-serine is an endogenous neurotransmitter that binds to the NMDA receptor, thereby increasing the affinity for glutamate, and the potential for excitotoxicity. The primary source of D-serine in vivo is enzymatic racemization by serine racemase (SR).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::79cef59996262d85e19bfd01a1707c22
https://doi.org/10.1111/j.1471-4159.2011.07601.x

Zobrazit plný text záznamu

Blepharospasm in a multiplex African-American pedigree

Autor: Jianfeng Xiao, Satya R. Vemula, Misty M. Thompson, Mark S. LeDoux

Publikováno v: Journal of the neurological sciences. 362

Background Isolated blepharospasm (BSP) is a late-onset focal dystonia characterized by involuntary contractions of the orbicularis oculi muscles. Genetic studies of BSP have been limited by the paucity of large multiplex pedigrees. Although sequence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4879a4ea40c481534158770b63c131
https://pubmed.ncbi.nlm.nih.gov/26944167

Zobrazit plný text záznamu

Regional Astrogliosis in the Mouse Hypothalamus in Response to Obesity

Autor: Laura B. Buckman, Misty M. Thompson, Heidi N. Moreno, Kate L. J. Ellacott

Obesity is associated with chronic low-grade inflammation in peripheral tissues, which contributes to the development of comorbidities such as insulin resistance and cardiovascular disease. While less extensively characterized, obesity also promotes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4396b94e6c211093f16cf789ab60a2f8
https://europepmc.org/articles/PMC4048830/

Zobrazit plný text záznamu

Clinical and genetic features of cervical dystonia in a large multicenter cohort

Publikováno v: Neurology: Genetics

Objective: To characterize the clinical and genetic features of cervical dystonia (CD). Methods: Participants enrolled in the Dystonia Coalition biorepository (NCT01373424) with initial manifestation as CD were included in this study (n = 1,000). Dat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5463d489d1eaa29c44d569f560f3eee2
https://doi.org/10.1212/nxg.0000000000000069

Zobrazit plný text záznamu

D-Serine Production, Degradation, and Transport in ALS: Critical Role of Methodology

Autor: Misty M. Thompson, John C. Marecki, John P. Crow

Publikováno v: Neurology Research International, Vol 2012 (2012)
Neurology Research International

In mammalian systems, D-serine is perhaps the most biologically active D-amino acid described to date. D-serine is a coagonist at the NMDA-receptor, and receptor activation is dependent on D-serine binding. Because D-serine binding dramatically incre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb471408392aedb598f93eaf6d5bde57
https://doaj.org/article/e26d26f5a474455487111fef83473e86

Zobrazit plný text záznamu