Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Misty L Kuhn"'
Autor:
Linda I Hu, Ekaterina V Filippova, Joseph Dang, Sergii Pshenychnyi, Jiapeng Ruan, Olga Kiryukhina, Wayne F Anderson, Misty L Kuhn, Alan J Wolfe
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0207563 (2018)
Spermidine N-acetyltransferase (SpeG) acetylates and thus neutralizes toxic polyamines. Studies indicate that SpeG plays an important role in virulence and pathogenicity of many bacteria, which have evolved SpeG-dependent strategies to control polyam
Externí odkaz:
https://doaj.org/article/cb581f9c1c9948ec955646c89a49e2ed
Autor:
Misty L Kuhn, Bozena Zemaitaitis, Linda I Hu, Alexandria Sahu, Dylan Sorensen, George Minasov, Bruno P Lima, Michael Scholle, Milan Mrksich, Wayne F Anderson, Bradford W Gibson, Birgit Schilling, Alan J Wolfe
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94816 (2014)
The emerging view of Nε-lysine acetylation in eukaryotes is of a relatively abundant post-translational modification (PTM) that has a major impact on the function, structure, stability and/or location of thousands of proteins involved in diverse cel
Externí odkaz:
https://doaj.org/article/e07c33fb85bf44c1961f778e81f862e6
Autor:
Carlos M Figueroa, Misty L Kuhn, Christine A Falaschetti, Ligin Solamen, Kenneth W Olsen, Miguel A Ballicora, Alberto A Iglesias
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66824 (2013)
ADP-glucose pyrophosphorylase regulates the synthesis of glycogen in bacteria and of starch in plants. The enzyme from plants is mainly activated by 3-phosphoglycerate and is a heterotetramer comprising two small and two large subunits. Here, we foun
Externí odkaz:
https://doaj.org/article/e2d4a8a5b015407da89ef46891f6d84e
Autor:
Sofiya Tsimbalyuk, Aleksander Shornikov, Parul Srivastava, Van Thi Bich Le, Imani Warren, Yogesh B. Khandokar, Misty L. Kuhn, Jade K. Forwood
Publikováno v:
Cells, Vol 12, Iss 14, p 1829 (2023)
Polyamines are simple yet critical molecules with diverse roles in numerous pathogenic and non-pathogenic organisms. Regulating polyamine concentrations affects the transcription and translation of genes and proteins important for cell growth, stress
Externí odkaz:
https://doaj.org/article/94572e486c244459aa8fd536b1bf03cc
Autor:
Michael J. Wolyniak, Jing Zhang, Sue Elen DeChenne‐Peters, Misty L. Kuhn, David Hecht, Courtney Koletar, Nicole Galport, Rebecca Eddy, Joseph J. Provost, Jessica Bell, J. E. Bell
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c367712ee6823410ed4075062c4413e5
https://doi.org/10.1096/fasebj.2022.36.s1.0r707
https://doi.org/10.1096/fasebj.2022.36.s1.0r707
Autor:
Kristen M. Jew, Van Thi Bich Le, Kiana Amaral, Allysa Ta, Nina M. Nguyen May, Melissa Law, Nicole Adelstein, Misty L. Kuhn
Publikováno v:
Frontiers in Microbiology, Vol 12 (2022)
Acetylation is a protein post-translational modification (PTM) that can affect a variety of cellular processes. In bacteria, two PTM Nε-acetylation mechanisms have been identified: non-enzymatic/chemical acetylation via acetyl phosphate or acetyl co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::256da1209e277afb9a399312d766a597
https://www.frontiersin.org/articles/10.3389/fmicb.2021.805181/full
https://www.frontiersin.org/articles/10.3389/fmicb.2021.805181/full
Publikováno v:
Protein Sci
The SpeG spermidine/spermine N-acetyltransferase (SSAT) from Escherichia coli belongs to the Gcn5-related N-acetyltransferase (GNAT) superfamily of proteins. In vitro characterization of this enzyme shows it acetylates the polyamines spermine and spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ccfedf946f8c12cad37ceac96fb79f
https://europepmc.org/articles/PMC8138529/
https://europepmc.org/articles/PMC8138529/
Autor:
Van Thi Bich Le, Paloma Boeck, Ee Qi Lim, Ee Qing Lim, Allan Solis, Misty L. Kuhn, Jade K. Forwood, Rosselini Renolo, Darwin Gawat, Sofiya Tsimbalyuk
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences
Polyamines regulate many important biological processes including gene expression, intracellular signaling, and biofilm formation. Their intracellular concentrations are tightly regulated by polyamine transport systems and biosynthetic and catabolic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8e6d31c6ca073cbd88cf983f40e7ff
https://doi.org/10.3389/fmolb.2021.645768
https://doi.org/10.3389/fmolb.2021.645768
Autor:
Jackson T. Baumgartner, Thahani S. Habeeb Mohammad, Mateusz P. Czub, Karolina A. Majorek, Xhulio Arolli, Cillian Variot, Madison Anonick, Wladek Minor, Miguel A. Ballicora, Daniel P. Becker, Misty L. Kuhn
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Enzymes in the Gcn5-related N-acetyltransferase (GNAT) superfamily are widespread and critically involved in multiple cellular processes ranging from antibiotic resistance to histone modification. While acetyl transfer is the most widely catalyzed re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e205eebad118147e9aa7b4d7b85260f
https://www.frontiersin.org/articles/10.3389/fmolb.2021.646046/full
https://www.frontiersin.org/articles/10.3389/fmolb.2021.646046/full
Publikováno v:
Microbiology (Reading)
Biofilm formation in the human intestinal pathogen Vibrio cholerae is in part regulated by norspermidine, spermidine and spermine. V. cholerae senses these polyamines through a signalling pathway consisting of the periplasmic protein, NspS, and the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e10c2bff9e2957dce22906d7d88faaed
https://pubmed.ncbi.nlm.nih.gov/33502310
https://pubmed.ncbi.nlm.nih.gov/33502310