Structure-activity relationship and cardiac safety of 2-aryl-2-(pyridin-2-yl)acetamides as a new class of broad-spectrum anticonvulsants derived from Disopyramide.

Autor: Dawidowski M; Department of Drug Technology and Pharmaceutical Biotechnology, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland. Electronic address: maciej.dawidowski@wum.edu.pl., Król M; Department of Drug Technology and Pharmaceutical Biotechnology, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland., Szulczyk B; Department of Drug Technology and Pharmaceutical Biotechnology, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland; Laboratory of Physiology and Pathophysiology, Centre for Preclinical Research, Medical University of Warsaw, Banacha 1B, 02-097 Warsaw, Poland., Chodkowski A; Department of Drug Technology and Pharmaceutical Biotechnology, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland., Podsadni P; Department of Drug Technology and Pharmaceutical Biotechnology, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland., Konopelski P; Department of Experimental Physiology and Pathophysiology, Centre for Preclinical Research, Medical University of Warsaw, Banacha 1B, 02-097 Warsaw, Poland., Ufnal M; Department of Experimental Physiology and Pathophysiology, Centre for Preclinical Research, Medical University of Warsaw, Banacha 1B, 02-097 Warsaw, Poland., Szuberski P; Department of Drug Technology and Pharmaceutical Biotechnology, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland., Wróbel MZ; Department of Drug Technology and Pharmaceutical Biotechnology, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland., Zhang Y; School of Physiology, Pharmacology and Neuroscience, Faculty of Medical Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom., El Harchi A; School of Physiology, Pharmacology and Neuroscience, Faculty of Medical Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom., Hancox JC; School of Physiology, Pharmacology and Neuroscience, Faculty of Medical Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom., Jarkovska D; Department of Physiology, Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 1655/76, 323 00 Pilsen, Czech Republic., Mistrova E; Department of Physiology, Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 1655/76, 323 00 Pilsen, Czech Republic., Sviglerova J; Department of Physiology, Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 1655/76, 323 00 Pilsen, Czech Republic., Štengl M; Department of Physiology, Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 1655/76, 323 00 Pilsen, Czech Republic., Popowicz GM; Institute of Structural Biology, Helmholtz Zentrum München, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany., Turło J; Department of Drug Technology and Pharmaceutical Biotechnology, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2020 May; Vol. 98, pp. 103717. Date of Electronic Publication: 2020 Mar 05.

Autophagy and mitophagy as potential therapeutic targets in diabetic heart condition: Harnessing the power of nanotheranostics.

Autor: Nag, Sagnik¹, Mitra, Oishi², Maturi, Bhanu³, Kaur, Simran Preet⁴, Saini, Ankita⁴, Nama, Muskan², Roy, Soumik⁵, Samanta, Souvik², Chacko, Leena⁶, Dutta, Rohan², Sayana, Suresh Babu⁷, Subramaniyan, Vetriselvan¹, Bhatti, Jasvinder Singh⁸ jasvinder.bhatti@cup.edu.in, Kandimalla, Ramesh⁹ ramesh.kandimalla@gmail.com

Publikováno v: Asian Journal of Pharmaceutical Sciences. Jun2024, Vol. 19 Issue 3, p1-23. 23p.

Effect of induced hepatic dysfunction on the innervation of the rat heart

Autor: Mistrova, E., Bludovska, M., Jarkovska, D., Kotyzova, Slavikova, J., Dvorakova, M. Chottova

Publikováno v: In Autonomic Neuroscience: Basic and Clinical November 2015 192:48-49

Expression of classical mediators in hearts of rats with hepatic dysfunction.

Autor: Jarkovska D; a Biomedical Center, Faculty of Medicine in Pilsen, Charles University, alej Svobody 1655/76, Pilsen 323 00, Czech Republic.; b Department of Physiology, Faculty of Medicine in Pilsen, Charles University, alej Svobody 1655/76, Pilsen 323 00, Czech Republic., Bludovska M; a Biomedical Center, Faculty of Medicine in Pilsen, Charles University, alej Svobody 1655/76, Pilsen 323 00, Czech Republic.; c Department of Pharmacology and Toxicology, Faculty of Medicine in Pilsen, Charles University, alej Svobody 1655/76, Pilsen 323 00, Czech Republic., Mistrova E; a Biomedical Center, Faculty of Medicine in Pilsen, Charles University, alej Svobody 1655/76, Pilsen 323 00, Czech Republic.; b Department of Physiology, Faculty of Medicine in Pilsen, Charles University, alej Svobody 1655/76, Pilsen 323 00, Czech Republic., Krizkova V; d Department of Histology and Embryology, Faculty of Medicine in Pilsen, Charles University, Lidicka 1, Pilsen 323 00, Czech Republic., Kotyzova D; c Department of Pharmacology and Toxicology, Faculty of Medicine in Pilsen, Charles University, alej Svobody 1655/76, Pilsen 323 00, Czech Republic., Kubikova T; a Biomedical Center, Faculty of Medicine in Pilsen, Charles University, alej Svobody 1655/76, Pilsen 323 00, Czech Republic.; d Department of Histology and Embryology, Faculty of Medicine in Pilsen, Charles University, Lidicka 1, Pilsen 323 00, Czech Republic., Slavikova J; a Biomedical Center, Faculty of Medicine in Pilsen, Charles University, alej Svobody 1655/76, Pilsen 323 00, Czech Republic., Erek SN; b Department of Physiology, Faculty of Medicine in Pilsen, Charles University, alej Svobody 1655/76, Pilsen 323 00, Czech Republic., Djordjevic A; b Department of Physiology, Faculty of Medicine in Pilsen, Charles University, alej Svobody 1655/76, Pilsen 323 00, Czech Republic., Chottova Dvorakova M; a Biomedical Center, Faculty of Medicine in Pilsen, Charles University, alej Svobody 1655/76, Pilsen 323 00, Czech Republic.; b Department of Physiology, Faculty of Medicine in Pilsen, Charles University, alej Svobody 1655/76, Pilsen 323 00, Czech Republic.

Publikováno v: Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2017 Nov; Vol. 95 (11), pp. 1351-1359. Date of Electronic Publication: 2017 Jul 26.

Role of substance P in the cardiovascular system.

Autor: Mistrova E; Department of Physiology, Faculty of Medicine in Pilsen, Charles University in Prague, Pilsen, Czech Republic; Biomedical Center, Faculty of Medicine in Pilsen, Charles University in Prague, Pilsen, Czech Republic., Kruzliak P; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Comenius University, Bratislava, Slovak Republic; 2(nd) Department of Internal Medicine, Faculty of Medicine, Masaryk University, Brno, Czech Republic. Electronic address: kruzliakpeter@gmail.com., Chottova Dvorakova M; Department of Physiology, Faculty of Medicine in Pilsen, Charles University in Prague, Pilsen, Czech Republic; Biomedical Center, Faculty of Medicine in Pilsen, Charles University in Prague, Pilsen, Czech Republic.

Publikováno v: Neuropeptides [Neuropeptides] 2016 Aug; Vol. 58, pp. 41-51. Date of Electronic Publication: 2015 Dec 08.